Introduction

SUMMARY: Sipros/ProRata is an open-source software package for end-to-end data analysis in a wide variety of community proteomics measurements. A database-searching program, Sipros 3.0, was developed for accurate general-purpose protein identification and broad-range post-translational modification searches. Hybrid Message Passing Interface/OpenMP parallelism of the new Sipros architecture allowed its computation to be scalable from desktops to supercomputers. The upgraded ProRata 3.0 performs label-free quantification and isobaric chemical labeling quantification in addition to metabolic labeling quantification. Sipros/ProRata is a versatile informatics system that enables identification and quantification of proteins and their variants in many types of community proteomics studies. AVAILABILITY: Both programs are freely available under the GNU GPL license at Sipros.omicsbio.org and ProRata.omicsbio.org.

Publications

  1. Sipros/ProRata: a versatile informatics system for quantitative community proteomics.
    Cite this
    Wang Y, Ahn TH, Li Z, Pan C, 2013-08-01 - Bioinformatics (Oxford, England)
  2. Exhaustive database searching for amino acid mutations in proteomes.
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    Hyatt D, Pan C, 2012-07-01 - Bioinformatics (Oxford, England)
  3. Quantitative tracking of isotope flows in proteomes of microbial communities.
    Cite this
    Pan C, Fischer CR, Hyatt D, Bowen BP, Hettich RL, Banfield JF, 2011-04-01 - Molecular & cellular proteomics : MCP

Credits

  1. Yingfeng Wang
    Developer

    Computer Science and Mathematics Division, Oak Ridge National Laboratory and Graduate School of Genome Science and Technology, United States of America

  2. Tae-Hyuk Ahn
    Developer

  3. Zhou Li
    Developer

  4. Chongle Pan
    Investigator

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Summary
AccessionBT002378
Tool TypeApplication
Category
PlatformsLinux/Unix
TechnologiesC++
User InterfaceTerminal Command Line
Download Count0
Submitted ByChongle Pan