Introduction

SUMMARY: We proposed a tool named MetaTISA with an aim to improve TIS prediction of current gene-finders for metagenomes. The method employs a two-step strategy to predict translation initiation sites (TISs) by first clustering metagenomic fragments into phylogenetic groups and then predicting TISs independently for each group in an unsupervised manner. As evaluated on experimentally verified TISs, MetaTISA greatly improves the accuracies of TIS prediction of current gene-finders. AVAILABILITY: The C++ source code is freely available under the GNU GPL license via http://mech.ctb.pku.edu.cn/MetaTISA/.

Publications

  1. MetaTISA: Metagenomic Translation Initiation Site Annotator for improving gene start prediction.
    Cite this
    Hu GQ, Guo JT, Liu YC, Zhu H, 2009-07-01 - Bioinformatics (Oxford, England)

Credits

  1. Gang-Qing Hu
    Developer

  2. Jiang-Tao Guo
    Developer

  3. Yong-Chu Liu
    Developer

  4. Huaiqiu Zhu
    Investigator

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Summary
AccessionBT002446
Tool TypeApplication
Category
PlatformsLinux/Unix
TechnologiesC++
User InterfaceTerminal Command Line
Download Count0
Submitted ByHuaiqiu Zhu