Introduction

The reconstruction of neuronal populations, a key step in understanding neural circuits, remains a challenge in the presence of densely packed neurites. Here we achieved automatic reconstruction of neuronal populations by partially mimicking human strategies to separate individual neurons. For populations not resolvable by other methods, we obtained recall and precision rates of approximately 80%. We also demonstrate the reconstruction of 960 neurons within 3 h.

Publications

  1. NeuroGPS-Tree: automatic reconstruction of large-scale neuronal populations with dense neurites.
    Cite this
    Quan T, Zhou H, Li J, Li S, Li A, Li Y, Lv X, Luo Q, Gong H, Zeng S, 2016-01-01 - Nature methods

Credits

  1. Tingwei Quan
    Developer

    School of Mathematics and Statistics, Hubei University of Education, China

  2. Hang Zhou
    Developer

    Department of Biomedical Engineering, School of Life Science and Technology, China

  3. Jing Li
    Developer

    Department of Biomedical Engineering, School of Life Science and Technology, China

  4. Shiwei Li
    Developer

    Department of Biomedical Engineering, School of Life Science and Technology, China

  5. Anan Li
    Developer

    Department of Biomedical Engineering, School of Life Science and Technology, China

  6. Yuxin Li
    Developer

    Department of Biomedical Engineering, School of Life Science and Technology, China

  7. Xiaohua Lv
    Developer

    Department of Biomedical Engineering, School of Life Science and Technology, China

  8. Qingming Luo
    Developer

    Department of Biomedical Engineering, School of Life Science and Technology, China

  9. Hui Gong
    Developer

    Department of Biomedical Engineering, School of Life Science and Technology, China

  10. Shaoqun Zeng
    Investigator

    Department of Biomedical Engineering, School of Life Science and Technology, China

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Summary
AccessionBT006147
Tool TypeApplication
Category
PlatformsWindows
TechnologiesC++
User InterfaceTerminal Command Line
Download Count0
Country/RegionChina
Submitted ByShaoqun Zeng