Introduction

We describe miTRATA, the first web-based tool for microRNA Truncation and Tailing Analysis--the analysis of 3' modifications of microRNAs including the loss or gain of nucleotides relative to the canonical sequence. miTRATA is implemented in Python (version 3) and employs parallel processing modules to enhance its scalability when analyzing multiple small RNA (sRNA) sequencing datasets. It utilizes miRBase, currently version 21, as a source of known microRNAs for analysis. miTRATA notifies user(s) via email to download as well as visualize the results online. miTRATA's strengths lie in (i) its biologist-focused web interface, (ii) improved scalability via parallel processing and (iii) its uniqueness as a webtool to perform microRNA truncation and tailing analysis.miTRATA is developed in Python and PHP. It is available as a web-based application from https://wasabi.dbi.udel.edu/∼apps/ta/.meyers@dbi.udel.eduSupplementary data are available at Bioinformatics online.

Publications

  1. miTRATA: a web-based tool for microRNA Truncation and Tailing Analysis.
    Cite this
    Patel P, Ramachandruni SD, Kakrana A, Nakano M, Meyers BC, 2016-02-01 - Bioinformatics (Oxford, England)

Credits

  1. Parth Patel
    Developer

  2. S Deepthi Ramachandruni
    Developer

  3. Atul Kakrana
    Developer

  4. Mayumi Nakano
    Developer

    Department of Plant and Soil Sciences, University of Delaware, United States of America

  5. Blake C Meyers
    Investigator

    Delaware Biotechnology Institute and Department of Plant and Soil Sciences, University of Delaware, United States of America

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Summary
AccessionBT006969
Tool TypeApplication
Category
PlatformsLinux/Unix
Technologies
User InterfaceTerminal Command Line
Download Count0
Country/RegionUnited States of America
Submitted ByBlake C Meyers