Gene

Symbol	CVD Atlas ID	Species	Gene ID	Biotype	Chr	Start	End
hsa-mir-106a	CVDG000617	Homo sapiens	MI0000113	miRNA	-	-	-

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Disease or trait	Score
Atherosclerosis	0.58094
Acute coronary syndrome	0.52349
Aortic valve disease	0.52349
Cardiomyopathy	0.52349
Coronary artery disease	0.52349

Showing 1 to 5 of 19 entries

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Tissue/cell type	Disease	Condition 1	Condition 2	Alteration	log2FC	P value	Adjusted P value	Method	PMID
Blood	Coronary artery disease	Coronary artery disease	Control	Down	-0.578	NaN	-	Microarray	20595655
Plasma	Acute coronary syndrome	Acute coronary syndrome	Control	Down	-1.20	-	-	RNA-seq	31899480

Showing 1 to 2 of 2 entries

Genes with adjusted P value < 0.05 are included in plots.
Genes with |log2FC| > 1 and adjusted P value < 0.05 are considered as significant and are displayed in tables below.

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Dataset	Tissue/cell type	Reported disease	Mapped disease	log2FC	P value	Adjusted P value	Method	GEO accession
No data available in table

Showing 0 to 0 of 0 entries

About the 'Score': Q10: Detailed description of the RNADisease Scoring System

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Reported disease	Mapped disease	RNADisease score	PMID	Gene link
Abdominal Aortic Aneurysm	Abdominal aortic aneurysm	0.99998	32767336	RNADisease
Acute Coronary Syndrome	Acute coronary syndrome	0.694506	32356454	RNADisease
Aortic Stenosis	Aortic valve stenosis	0.328976	27129184	RNADisease
Aortic Valve Disease	Aortic valve disease	0.973352	27129184	RNADisease
Aortopathy	Aortic valve disease	0.328976	31963884	RNADisease
Atherosclerosis	Atherosclerosis	0.99998	32626987	RNADisease
Atherosclerosis	Atherosclerosis	0.99998	32633398	RNADisease
Atrial Fibrillation	Atrial fibrillation	0.328976	24824214	RNADisease
Bicuspid Aortic Valve Disease	Bicuspid aortic valve disease	0.328976	29462317	RNADisease
Cardiomyopathy	Cardiomyopathy	0.328976	30346833	RNADisease

Showing 1 to 10 of 21 entries

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Reported disease/trait	Mapped trait	Tissue	Effect size	P value	Method	Publication	PMID	Gene link
No data available in table

Showing 0 to 0 of 0 entries

Link to HMDD v4.0: https://www.cuilab.cn/hmdd

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Reported disease	Mapped disease	Category	Description	Publication
Aortic Aneurysm, Abdominal	Abdominal aortic aneurysm	genetics_overexpression_promote	To determine the potential role of miR-106a in the pathogenesis of AAA, miR-106a was overexpressed in vascular smooth muscle cells (VSMCs), and then cell viability and apoptosis were evaluated by performing CCK-8 assay and flow cytometry, respectively.	32767336
Atherosclerosis	Atherosclerosis	genetics_overexpression_promote	CONCLUSION: Overexpression of GASL1 might suppress ox-LDL-induced HUVEC cell viability, apoptosis, and inflammation by regulating miR-106a/LKB1 axis.	36627571
Coronary Artery Disease	Coronary artery disease	circulation_biomarker_diagnosis_up	The plasma level of miR-106a was positively correlated with the level of ox-LDL and negatively correlated with the level of 25 (OH) D3 in patients with CAD.	31625362
Ischemic Stroke	Ischemic stroke	circulation_biomarker_diagnosis_ns	At the same time, we found marked increases of serum TUG1, LINC00657, and miR-9 and a marked decrease of serum miR-106a in diabetic patients who had stroke relative to those without stroke.	35237654

Showing 1 to 4 of 4 entries

Reported disease	Mapped disease	Species	Description	Publication

Variant	Reported disease/trait	Mapped disease/trait	Beta	Standard error	P value	Odds ratio	Ancestry	Dataset	Link

Tissue

Ancestry

Reported disease/trait	Mapped disease/trait	Tissue	Best coloc SNP	GWAS risk SNP	SNP.PP.H4	PP.H4.abf	Ancestry	Dataset

Link to PedAM: http://www.unimd.org/pedam/

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Variant	Reported disease	Mapped disease	Description	PMID
No data available in table

Showing 0 to 0 of 0 entries

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Variant	Disease	Pre miRNA	Region	Mature miRNA	△G	Exp	PMID
No data available in table

Showing 0 to 0 of 0 entries

Link to HMDD v4.0: https://www.cuilab.cn/hmdd

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Reported disease	Gene	Category	Description	Publication
No data available in table

Showing 0 to 0 of 0 entries

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SNP	Reported disease	Mapped disease	Description	PMID
No data available in table

Showing 0 to 0 of 0 entries

Name	Delta beta	P value	Adjusted P value	Reported disease	Mapped disease	Dataset

Name	Relation to gene	Delta beta	P value	Adjusted P value	Tissue	Reported disease	Mapped disease	Condition 1	Condition 2	PMID

Link to HMDD v4.0: https://www.cuilab.cn/hmdd

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Reported disease	Mapped disease	Category	Description	Publication
No data available in table

Showing 0 to 0 of 0 entries

Reported disease	Mapped disease	Species	Description	Publication

UniProt ID	Reported disease	Mapped disease	Average log2FC	P value	Dataset

Gene	PharmGKB gene ID	Chemical	PharmGKB chemical ID	Evidence	Association	PK/PD	PMID

About the Inference score: https://ctdbase.org/help/diseaseChemDetailHelp.jsp

Chemical name	Chemical ID	Reported disease	Mapped disease	Inference score	#PMIDs	Gene link

Gene information

Gene priorization

Gene ontology

Differentially expressed gene

Gene-disease association

GTEx expression level

GWAS significantly associated SNP

GWAS colocalization

Variant-disease association

Differentially methylated position

Gene-disease association

Differential expressed protein

Gene-chemical association