Gene

Symbol	CVD Atlas ID	Species	Gene ID	Biotype	Chr	Start	End
CDKN2B-AS1	CVDG000041	Homo sapiens	ENSG00000240498	lncRNA	9	21994139	22128103

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Disease or trait	Score
Coronary artery disease	0.93775
Myocardial infarction	0.91025
Intracranial aneurysm	0.90795
Stroke	0.88797
Ischemic stroke	0.88368

Showing 1 to 5 of 36 entries

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Tissue/cell type	Disease	Condition 1	Condition 2	Alteration	log2FC	P value	Adjusted P value	Method	PMID
Ascending aorta	Stanford type A aortic dissection	Stanford type A aortic dissection	Control	Up	6.42	6.20e-14	5.10e-12	RNA-seq	33066131

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Genes with adjusted P value < 0.05 are included in plots.
Genes with |log2FC| > 1 and adjusted P value < 0.05 are considered as significant and are displayed in tables below.

Tissue

Top genes selected

by median of log2FC

by number of datasets

Search:

Dataset	Tissue/cell type	Reported disease	Mapped disease	log2FC	P value	Adjusted P value	Method	GEO accession
CVDS000005	Aorta	Thoracic aortic dissection	Thoracic aortic dissection	2.08	1.59e-4	3.63e-3	RNA-seq	GSE107844
CVDS000013	Gastrocnemius	Critical limb ischemia	Critical limb ischemia	3.12	1.49e-14	1.43e-12	RNA-seq	GSE120642
CVDS000021	Heart left ventricle	Dilated cardiomyopathy	Dilated cardiomyopathy	-1.13	1.72e-10	8.47e-10	RNA-seq	GSE141910
CVDS000022	Heart left ventricle	Hypertrophic cardiomyopathy	Hypertrophic cardiomyopathy	-1.35	2.97e-5	1.97e-4	RNA-seq	GSE141910
CVDS000025	Aorta	Aortic dissection	Aortic dissection	5.02	8.81e-14	1.08e-10	RNA-seq	GSE147026
CVDS000026	Aorta	Aortic dissection	Aortic dissection	6.58	5.33e-15	6.02e-13	RNA-seq	GSE153434
CVDS000028	Arterial blood vessel	Intracranial aneurysm	Intracranial aneurysm	3.42	5.92e-5	2.97e-3	RNA-seq	GSE158558
CVDS000069	Intracranial artery	Intracranial aneurysm	Intracranial aneurysm	3.51	3.45e-8	1.25e-6	RNA-seq	GSE66238
CVDS000517	Cardiac organoid	Myocardial Infarction	Myocardial infarction	1.02	7.20e-37	2.36e-34	RNA-seq	GSE113871
CVDS000527	Heart left ventricle	Left Ventricle Heart Failure	Left ventricle heart failure	-2.00	1.74e-3	4.09e-2	RNA-seq	GSE120852

Showing 1 to 10 of 22 entries

About the 'Score': Q10: Detailed description of the RNADisease Scoring System

Search:

Reported disease	Mapped disease	RNADisease score	PMID	Gene link
No data available in table

Showing 0 to 0 of 0 entries

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Reported disease/trait	Mapped trait	Tissue	Effect size	P value	Method	Publication	PMID	Gene link
High-Density Lipoproteins	High density lipoprotein cholesterol measurement	Whole Blood	6.98	2.99e-12	Summary-PrediXcan(S-PrediXcan)	TWASP000054	29739930	TWAS Atlas
High-Density Lipoproteins	High density lipoprotein cholesterol measurement	Skin Sun Exposed	6.9	5.27e-12	Summary-PrediXcan(S-PrediXcan)	TWASP000054	29739930	TWAS Atlas
High-Density Lipoproteins	High density lipoprotein cholesterol measurement	Skin Sun Exposed	-	1.69e-08	Summary-MultiXcan(S-MultiXcan)	TWASP000056	30668570	TWAS Atlas
High-Density Lipoproteins	High density lipoprotein cholesterol measurement	Cross-tissue	-	1.22e-06	UTMOST	TWASP000100	32425817	TWAS Atlas
High-Density Lipoproteins	High density lipoprotein cholesterol measurement	Aortic Artery	-	4.73e-12	Probabilistic Transcriptome-Wide Association(PTWAS)	TWASP000141	32912253	TWAS Atlas
High-Density Lipoproteins	High density lipoprotein cholesterol measurement	Skin Sun Exposed	4.58	4.73e-06	FUSION	TWASP000150	31648709	TWAS Atlas
High-Density Lipoproteins	High density lipoprotein cholesterol measurement	Esophagus Muscularis	4.97	6.53e-07	FUSION	TWASP000150	31648709	TWAS Atlas

Showing 1 to 7 of 7 entries

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Reported disease	Mapped disease	Category	Description	Publication
No data available in table

Showing 0 to 0 of 0 entries

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Reported disease	Mapped disease	Species	Description	Publication
No data available in table

Showing 0 to 0 of 0 entries

Variant	Reported disease/trait	Mapped disease/trait	Beta	Standard error	P value	Odds ratio	Ancestry	Dataset	Link

Tissue

Ancestry

Reported disease/trait	Mapped disease/trait	Tissue	Best coloc SNP	GWAS risk SNP	SNP.PP.H4	PP.H4.abf	Ancestry	Dataset

Link to PedAM: http://www.unimd.org/pedam/

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Variant	Reported disease	Mapped disease	Description	PMID
No data available in table

Showing 0 to 0 of 0 entries

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Variant	Disease	Pre miRNA	Region	Mature miRNA	△G	Exp	PMID
No data available in table

Showing 0 to 0 of 0 entries

Link to HMDD v4.0: https://www.cuilab.cn/hmdd

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Reported disease	Gene	Category	Description	Publication
No data available in table

Showing 0 to 0 of 0 entries

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SNP	Reported disease	Mapped disease	Description	PMID
No data available in table

Showing 0 to 0 of 0 entries

Name	Delta beta	P value	Adjusted P value	Reported disease	Mapped disease	Dataset

Name	Relation to gene	Delta beta	P value	Adjusted P value	Tissue	Reported disease	Mapped disease	Condition 1	Condition 2	PMID

Link to HMDD v4.0: https://www.cuilab.cn/hmdd

Reported disease	Mapped disease	Category	Description	Publication

Reported disease	Mapped disease	Species	Description	Publication

UniProt ID	Reported disease	Mapped disease	Average log2FC	P value	Dataset

Gene	PharmGKB gene ID	Chemical	PharmGKB chemical ID	Evidence	Association	PK/PD	PMID

About the Inference score: https://ctdbase.org/help/diseaseChemDetailHelp.jsp

Chemical name	Chemical ID	Reported disease	Mapped disease	Inference score	#PMIDs	Gene link

Gene information

Gene priorization

Gene ontology

Differentially expressed gene

Gene-disease association

GTEx expression level

GWAS significantly associated SNP

GWAS colocalization

Variant-disease association

Differentially methylated position

Gene-disease association

Differential expressed protein

Gene-chemical association