Basic information
GenBank ID	AY687391
Alias	GmSARK
Organism	Soybean (Glycine max)
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling:Nutrient recycling
Effect for Senescence	promote
Gene Description	The conceptual protein product of GmSARK contains typical domains of LRR receptor-like kinases: a cytoplasmic domain with all the 11 kinase subdomains, a transmembrane domain and an extracelullar domain containing 9 Leucine-Rich Repeat (LRR) units that may act as a receptor. The expression of GmSARK in soybean leaves was up-regulated in all the three tested senescence systems: senescing cotyledons, dark-induced primary leaf senescence and the natural leaf senescence process after florescence. Furthermore, the RNA interference (RNAi)-mediated knocking-down of GmSARK dramatically retarded soybean leaf senescence.
Evidence	Genetic evidence:Transgene [Ref 1]
References	1: Li XP, Gan R, Li PL, Ma YY, Zhang LW, Zhang R, Wang Y, Wang NN Identification and functional characterization of a leucine-rich repeat receptor-like kinase gene that is involved in regulation of soybean leaf senescence. Plant Mol. Biol. 2006 Aug;61(6):829-44
Gene Ontology	biological process protein phosphorylation molecular function ATP binding protein binding protein kinase activity protein serine/threonine kinase activity
Sequence	AY687391.1 | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name GmSARK_RNAi Mutant/Transgenic transgenic Ecotype Soybean (Glycine max) Mutagenesis type RNAi
Mutated 2 Mutant name GVG:GmSARK Mutant/Transgenic transgenic Ecotype other Mutagenesis type transgene
Mutated 3 Mutant name ein2-1/GVG:GmSARK Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type cross
Mutated 4 Mutant name aux1-7/GVG:GmSARK Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type cross
miRNA Interaction
Details	target: AY687391  miRNA: gma-miR1507b miRNA: gma-miR1507b mfe: -28.6 kcal/mol  p-value: 0.002707  position:  2388  target 5' U     U         G    U 3'             GGAUG UGUGUGGAG GAGA              UCUGC ACAUACCUU CUCU   miRNA  3' G     U         A      5'  target: AY687391  miRNA: gma-miR1510a miRNA: gma-miR1510a mfe: -25.7 kcal/mol  p-value: 0.021689  position:  1836  target 5' A  A     U          U  U 3'             GG GGAAU GGUAAGGCAG CA              CC CCUUA CCAUUUUGUU GU   miRNA  3' C  A     U             U 5'  target: AY687391  miRNA: gma-miR1510b miRNA: gma-miR1510b mfe: -24.7 kcal/mol  p-value: 0.031831  position:  1836  target 5' A  A     U          U  U 3'             GG GGAAU GGUAAGGCAG CA              CC CCUUA CCAUUUUGUU GU   miRNA  3'    A     U               5'
Cross Link
Database Entry ID E-value Start End InterPro ID Description SUPERFAMILY SSF52058 1.1E-51 68 345 No hit NA PANTHER PTHR24420 0.0 86 969 No hit NA Pfam PF00560 0.2 160 181 IPR001611 Leucine-rich repeat Pfam PF12799 5.3E-8 279 316 IPR025875 Leucine rich repeat 4 Pfam PF11721 7.4E-56 402 586 IPR021720 Malectin SUPERFAMILY SSF56112 1.5E-81 647 937 IPR011009 Protein kinase-like domain ProSiteProfiles PS50011 37.9 663 976 IPR000719 Protein kinase, catalytic domain SMART SM00220 3.0E-29 663 934 IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain Pfam PF07714 3.6E-49 665 934 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain ProSitePatterns PS00108 NA 785 797 IPR008271 Serine/threonine-protein kinase, active site