Basic information
Locus name	AT4G26850
Alias	VTC2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	ascorbate biosynthesis
Effect for Senescence	promote
Gene Description	Encodes a novel protein involved in ascorbate biosynthesis, which was shown to catalyze the transfer of GMP from GDP-galactose to a variety of hexose-1-phosphate acceptors. Recessive mutation has a reduced amount of vitamin C, lower level of non-photochemical quenching, and reduced rate of conversion of violaxanthin to zeaxanthin in high light.
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Pavet V, Olmos E, Kiddle G, Mowla S, Kumar S, Antoniw J, Alvarez ME, Foyer CH. Ascorbic acid deficiency activates cell death and disease resistance responses in Arabidopsis. Plant Physiol. 2005 Nov;139(3):1291-303. Epub 2005 Oct 21.
Sequence	AT4G26850.1 | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name vtc2 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA
Mutated 2 Mutant name vtc2 Mutant/Transgenic Ecotype Col-0 Mutagenesis type T-DNA
Mutant Image
The mutants have a delayed senescence phenotype with smaller leaf cells than the wild type at leaf maturity. The vtc leaves have more glutathione than the wild type, with higher ratios of reduced glutathione to glutathione disulfide.