Basic information
Locus name	AT2G17790
Alias	VPS35A
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	protein transport
Effect for Senescence	delay
Gene Description	Encodes a protein with similarity to yeast VPS35 which encodes a component of the retromer involved in retrograde endosomal transport.
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Yamazaki M, Shimada T, Takahashi H, Tamura K, Kondo M, Nishimura M, Hara-Nishimura I. Arabidopsis VPS35, a retromer component, is required for vacuolar protein sorting and involved in plant growth and leaf senescence. Plant Cell Physiol. 2008 Feb;49(2):142-56. doi: 10.1093/pcp/pcn006. Epub 2008 Jan 25. Erratum in: Plant Cell Physiol. 2008 Apr;49(4):678.
Sequence	AT2G17790.1 | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name vps35a-1 (SALK_014345) Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA
Mutated 2 Mutant name vps35a-1 vps35b-2 vps35c-1 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type cross
Mutated 3 Mutant name vps35a-1 (SALK_014345) Mutant/Transgenic Ecotype Col-0 Mutagenesis type T-DNA
Mutated 4 Mutant name vps35a-1 vps35b-2 vps35c-1 Mutant/Transgenic Ecotype Col-0 Mutagenesis type cross
Mutant Image
vps35a-1 vps35c-1 exhibited no unusual phenotypes. On the other hand, vps35b-1 vps35c-1 and the triple mutant (vps35a-1 vps35b-2 vps35c-1) exhibited severe phenotypes: dwarfism, early leaf senescence