OMIX005710

1Summary
Title Single-cell profiling revealed tumor heterogeneity and microenvironment in surgically resectable esophageal squamous cell carcinoma with neoadjuvant chemoimmunotherapy
Description 46 samples
Organism Homo sapiens
Data Type Expression Profiling
Data Accessibility Open-access
BioProject PRJCA016745
Release Date 2024-01-23
Submitter Qiang Lu (luqiang@fmmu.edu.cn)
Organization Air Force Medical University
Submission Date 2024-01-19
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX005710-03 HRS849537 1 Expression Profiling 135.97 MB tar
OMIX005710-04 HRS849514 1 Expression Profiling 83.03 MB tar
OMIX005710-05 HRS849512 1 Expression Profiling 48.16 MB tar
OMIX005710-06 HRS849534 1 Expression Profiling 141.49 MB tar
OMIX005710-07 HRS849531 1 Expression Profiling 136.36 MB tar
OMIX005710-08 HRS849516 1 Expression Profiling 91.15 MB tar
OMIX005710-09 HRS849524 1 Expression Profiling 97.73 MB tar
OMIX005710-10 HRS849513 1 Expression Profiling 77.91 MB tar
OMIX005710-11 HRS849518 1 Expression Profiling 137.68 MB tar
OMIX005710-12 HRS849520 1 Expression Profiling 53 MB tar
OMIX005710-13 HRS849532 1 Expression Profiling 71 MB tar
OMIX005710-14 HRS849522 1 Expression Profiling 82.01 MB tar
OMIX005710-15 HRS849525 1 Expression Profiling 213.51 MB tar
OMIX005710-16 HRS849519 1 Expression Profiling 16.65 MB tar
OMIX005710-17 HRS849528 1 Expression Profiling 158.26 MB tar
OMIX005710-18 HRS849530 1 Expression Profiling 86.47 MB tar
OMIX005710-19 HRS849535 1 Expression Profiling 83.88 MB tar
OMIX005710-20 HRS849517 1 Expression Profiling 101.19 MB tar
OMIX005710-21 HRS849548 1 Expression Profiling 113.59 MB tar
OMIX005710-22 HRS849550 1 Expression Profiling 218.21 MB tar
OMIX005710-23 HRS849542 1 Expression Profiling 75.64 MB tar
OMIX005710-24 HRS849527 1 Expression Profiling 149.05 MB tar
OMIX005710-25 HRS849526 1 Expression Profiling 152.13 MB tar
OMIX005710-26 HRS849543 1 Expression Profiling 124.19 MB tar
OMIX005710-27 HRS849546 1 Expression Profiling 129.55 MB tar
OMIX005710-28 HRS849545 1 Expression Profiling 44.45 MB tar
OMIX005710-29 HRS849539 1 Expression Profiling 133.35 MB tar
OMIX005710-30 HRS849553 1 Expression Profiling 85.83 MB tar
OMIX005710-31 HRS849544 1 Expression Profiling 53 MB tar
OMIX005710-32 HRS849549 1 Expression Profiling 163.6 MB tar
OMIX005710-34 HRS849540 1 Expression Profiling 81.52 MB tar
OMIX005710-35 HRS849547 1 Expression Profiling 139.9 MB tar
OMIX005710-36 HRS849538 1 Expression Profiling 70.93 MB tar
OMIX005710-37 HRS849554 1 Expression Profiling 74.53 MB tar
OMIX005710-38 HRS849556 1 Expression Profiling 162.5 MB tar
OMIX005710-39 HRS849541 1 Expression Profiling 179.8 MB tar
OMIX005710-40 HRS849555 1 Expression Profiling 43.28 MB tar
OMIX005710-41 HRS849551 1 Expression Profiling 59.59 MB tar
OMIX005710-42 HRS849552 1 Expression Profiling 44.79 MB tar
OMIX005710-43 HRS849557 1 Expression Profiling 23.2 MB tar
OMIX005710-44 HRS849523 1 Expression Profiling 95.9 MB tar
OMIX005710-45 HRS849515 1 Expression Profiling 157.92 MB tar
OMIX005710-46 HRS849529 1 Expression Profiling 75.13 MB tar
OMIX005710-47 HRS849521 1 Expression Profiling 73.17 MB tar
OMIX005710-48 HRS849533 1 Expression Profiling 137.82 MB tar
OMIX005710-49 HRS849536 1 Expression Profiling 92.84 MB tar
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
Integrated single-cell and Mendelian randomization analyses: dissecting underlying causes of varied efficacy in immune neoadjuvant therapy for esophageal carcinoma Discover Oncology 2025-10 OMIX005710 Secondary use
AKB-9778-induced tumor vascular normalization enhances the efficacy of immunotherapy in oral cancer International Immunopharmacology 2025-02 OMIX005710 Secondary use
Discovery and validation of proliferative exhausted T cells as a favorable prognostic biomarker in esophageal squamous cell carcinoma Scientific Reports 2025-11 OMIX005710 Secondary use
An Immune-privileged niche mediates immunotherapy resistance in esophageal carcinoma Journal for Immunotherapy of Cancer 2026-01 OMIX005710 Secondary use
Single-cell profiling of response to neoadjuvant chemo-immunotherapy in surgically resectable esophageal squamous cell carcinoma Genome Medicine 2024-04 OMIX005710 Deposit
Functional heterogeneity of cancer-associated fibroblasts with distinct neoadjuvant immunotherapy plus chemotherapy response in esophageal squamous cell carcinoma Biomarker Research 2024-09 OMIX005710 Deposit
Constructing a Predictive Model for PD-1 Blockade Therapy in Pan-Cancer Based on Machine Learning Research Square 2025-04 OMIX005710 Secondary use
Single-cell RNA sequencing reveals adrb1 as a sympathetic nerve-regulated immune checkpoint driving T cell exhaustion and impacting immunotherapy in esophageal squamous cell carcinoma Frontiers in Immunology 2025-05 OMIX005710 Secondary use
Neoadjuvant therapy–associated malignant phenotype score predicts prognosis and highlights the roles of MIF signaling and DUXAP8 in ESCC Frontiers in Immunology 2026-01 OMIX005710 Secondary use
Construction of Metastasis Prediction Models and Screening of Anti-Metastatic Drugs Based on Pan-Cancer Single-Cell EMT Features International Journal of Molecular Sciences 2025-11 OMIX005710 Secondary use
Harnessing Single-Cell RNA-Seq for Computational Drug Repurposing in Cancer Immunotherapy Pharmaceuticals 2025-11 OMIX005710 Secondary use

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