OMIX005710

1Summary
Title Single-cell profiling revealed tumor heterogeneity and microenvironment in surgically resectable esophageal squamous cell carcinoma with neoadjuvant chemoimmunotherapy
Description 46 samples
Organism Homo sapiens
Data Type Expression Profiling by NGS
Data Accessibility Open-access
BioProject PRJCA016745
Release Date 2024-01-23
Submitter Qiang Lu (luqiang@fmmu.edu.cn)
Organization Air Force Medical University
Submission Date 2024-01-19
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX005710-03 HRS849537 1 Expression Profiling by NGS 135.97 MB tar
OMIX005710-04 HRS849514 1 Expression Profiling by NGS 83.03 MB tar
OMIX005710-05 HRS849512 1 Expression Profiling by NGS 48.16 MB tar
OMIX005710-06 HRS849534 1 Expression Profiling by NGS 141.49 MB tar
OMIX005710-07 HRS849531 1 Expression Profiling by NGS 136.36 MB tar
OMIX005710-08 HRS849516 1 Expression Profiling by NGS 91.15 MB tar
OMIX005710-09 HRS849524 1 Expression Profiling by NGS 97.73 MB tar
OMIX005710-10 HRS849513 1 Expression Profiling by NGS 77.91 MB tar
OMIX005710-11 HRS849518 1 Expression Profiling by NGS 137.68 MB tar
OMIX005710-12 HRS849520 1 Expression Profiling by NGS 53 MB tar
OMIX005710-13 HRS849532 1 Expression Profiling by NGS 71 MB tar
OMIX005710-14 HRS849522 1 Expression Profiling by NGS 82.01 MB tar
OMIX005710-15 HRS849525 1 Expression Profiling by NGS 213.51 MB tar
OMIX005710-16 HRS849519 1 Expression Profiling by NGS 16.65 MB tar
OMIX005710-17 HRS849528 1 Expression Profiling by NGS 158.26 MB tar
OMIX005710-18 HRS849530 1 Expression Profiling by NGS 86.47 MB tar
OMIX005710-19 HRS849535 1 Expression Profiling by NGS 83.88 MB tar
OMIX005710-20 HRS849517 1 Expression Profiling by NGS 101.19 MB tar
OMIX005710-21 HRS849548 1 Expression Profiling by NGS 113.59 MB tar
OMIX005710-22 HRS849550 1 Expression Profiling by NGS 218.21 MB tar
OMIX005710-23 HRS849542 1 Expression Profiling by NGS 75.64 MB tar
OMIX005710-24 HRS849527 1 Expression Profiling by NGS 149.05 MB tar
OMIX005710-25 HRS849526 1 Expression Profiling by NGS 152.13 MB tar
OMIX005710-26 HRS849543 1 Expression Profiling by NGS 124.19 MB tar
OMIX005710-27 HRS849546 1 Expression Profiling by NGS 129.55 MB tar
OMIX005710-28 HRS849545 1 Expression Profiling by NGS 44.45 MB tar
OMIX005710-29 HRS849539 1 Expression Profiling by NGS 133.35 MB tar
OMIX005710-30 HRS849553 1 Expression Profiling by NGS 85.83 MB tar
OMIX005710-31 HRS849544 1 Expression Profiling by NGS 53 MB tar
OMIX005710-32 HRS849549 1 Expression Profiling by NGS 163.6 MB tar
OMIX005710-34 HRS849540 1 Expression Profiling by NGS 81.52 MB tar
OMIX005710-35 HRS849547 1 Expression Profiling by NGS 139.9 MB tar
OMIX005710-36 HRS849538 1 Expression Profiling by NGS 70.93 MB tar
OMIX005710-37 HRS849554 1 Expression Profiling by NGS 74.53 MB tar
OMIX005710-38 HRS849556 1 Expression Profiling by NGS 162.5 MB tar
OMIX005710-39 HRS849541 1 Expression Profiling by NGS 179.8 MB tar
OMIX005710-40 HRS849555 1 Expression Profiling by NGS 43.28 MB tar
OMIX005710-41 HRS849551 1 Expression Profiling by NGS 59.59 MB tar
OMIX005710-42 HRS849552 1 Expression Profiling by NGS 44.79 MB tar
OMIX005710-43 HRS849557 1 Expression Profiling by NGS 23.2 MB tar
OMIX005710-44 HRS849523 1 Expression Profiling by NGS 95.9 MB tar
OMIX005710-45 HRS849515 1 Expression Profiling by NGS 157.92 MB tar
OMIX005710-46 HRS849529 1 Expression Profiling by NGS 75.13 MB tar
OMIX005710-47 HRS849521 1 Expression Profiling by NGS 73.17 MB tar
OMIX005710-48 HRS849533 1 Expression Profiling by NGS 137.82 MB tar
OMIX005710-49 HRS849536 1 Expression Profiling by NGS 92.84 MB tar
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
Integrated single-cell and Mendelian randomization analyses: dissecting underlying causes of varied efficacy in immune neoadjuvant therapy for esophageal carcinoma Discover Oncology 2025-10 OMIX005710 Secondary use
AKB-9778-induced tumor vascular normalization enhances the efficacy of immunotherapy in oral cancer International Immunopharmacology 2025-02 OMIX005710 Secondary use
Discovery and validation of proliferative exhausted T cells as a favorable prognostic biomarker in esophageal squamous cell carcinoma Scientific Reports 2025-11 OMIX005710 Secondary use
Single-cell profiling of response to neoadjuvant chemo-immunotherapy in surgically resectable esophageal squamous cell carcinoma Genome Medicine 2024-04 OMIX005710 Deposit
Functional heterogeneity of cancer-associated fibroblasts with distinct neoadjuvant immunotherapy plus chemotherapy response in esophageal squamous cell carcinoma Biomarker Research 2024-09 OMIX005710 Deposit
Constructing a Predictive Model for PD-1 Blockade Therapy in Pan-Cancer Based on Machine Learning Research Square 2025-04 OMIX005710 Secondary use
Single-cell RNA sequencing reveals adrb1 as a sympathetic nerve-regulated immune checkpoint driving T cell exhaustion and impacting immunotherapy in esophageal squamous cell carcinoma Frontiers in Immunology 2025-05 OMIX005710 Secondary use
Construction of Metastasis Prediction Models and Screening of Anti-Metastatic Drugs Based on Pan-Cancer Single-Cell EMT Features International Journal of Molecular Sciences 2025-11 OMIX005710 Secondary use
Harnessing Single-Cell RNA-Seq for Computational Drug Repurposing in Cancer Immunotherapy Pharmaceuticals 2025-11 OMIX005710 Secondary use

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