| Title | Metabolic Recoding of 5'-Methylthioadenosine- Mediated H3K79me1 Demethylation Antagonizes Cadmium-Induced Breast Cancer Progression by Maintaining Autophagic Flux |
|---|---|
| Description | For LC-MS analysis, a precooled methanol-water solution was utilized for the extraction of cellular metabolites, and the subsequent mass spectrometric information was acquired using a Nexera UPLC coupled to a Q Exactive high-resolution mass spectrometer. GC-MS analysis was conducted on a 7890B-5977A GC-MS system (Agilent Technologies, Santa Clara, CA, USA) equipped with a DB-5MS column, employing a temperature gradient and electron ionization (EI) for metabolite separation and detection. |
| Organism | Homo sapiens |
| Data Type | Metabolome Data by Mass Spectrometry (MS) |
| Data Accessibility | Open-access |
| BioProject | PRJCA033456 |
| Release Date | 2026-01-03 |
| Submitter | li li (laoweishuju@163.com) |
| Organization | Third Military Medical University(Army Medical University) |
| Submission Date | 2024-12-10 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX008219-01 | raw data | 15 | Metabolome Data by Mass Spectrometry (MS) | 1.94 GB | zip |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| 5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux | Advanced Science | 2025-09 | OMIX008223 OMIX008219 | Deposit |