Plant
Editosome
Database
Summary
| Editing Factor: | AEF1 |
| Synonym: | ATPF EDITING FACTOR 1 |
| Description: | Involved in RNA editing of plastid atpF and mitochondrial nad5; A loss-of-function mutation in ATPF EDITING FACTOR 1 (AEF1, AT3G22150) results in severe variegation, presumably due to decreased plastid ATP synthase levels; Loss of editing at the atpF site is coupled with a large decrease in splicing of the atpF transcript, even though the editing site is within an exon and 53 nucleotides distant from the splice site |
| Protein Family: | Pentatricopeptide repeat (PPR) protein |
| Subclass: | E |
| Physical Interaction: | NA |
| Construct Structure: | PLS-E |
| Gene ID & Species: | AT3G22150 (Arabidopsis thaliana) |
| Edited Gene(s): | atpF nad5 |
| Editing Type(s): | C-to-U (9) |
| Publication(s): |
[1] Multiple PPR Protein Interactions Are Involved in the RNA Editing System in Arabidopsis Mitochondria and Plastids, Proc Natl Acad Sci U S A, 2017. [doi:10.1073/pnas.1705815114] [2] AEF1/MPR25 is implicated in RNA editing of plastid atpF and mitochondrial nad5, and also promotes atpF splicing in Arabidopsis and rice, The Plant Journal, 2015. [doi:10.1111/tpj.12756] |
Editing Details
| Species | Gene ID | Organelle | Edited Gene | Position | Region | Nuclear Genome | Organelle Genome | Other Region | Other Position | Editing Type | Codon | Amino Acid | Molecular Effect | Experiment Details | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Arabidopsis thaliana | AT3G22150 | Plastid Chloroplast |
atpF | 92 | CDS | NA | NA | NA | NA | C-to-U | CCA=>CUA NA=>NA |
P=>L NA=>NA |
Recoding NA |
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| Arabidopsis thaliana | AT3G22150 | Mitochondrion | nad5 | 1580 | CDS | NA | NA | NA | NA | C-to-U | UCA=>UUA | S=>L | Recoding |
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Last update: Sep 2026
(version 2.0)