DEK46 - Plant Editosome Database - BIG Data Center

Summary

Editing Factor: DEK46
Synonym: Defective Kernel 46
Description: DEK46 functions in the C-to-U editing of D5-C22 of both introns, and the U base at this position is critical to intron splicing
Protein Family: PPR
Subclass: DYW
Construct Structure: PLS-E1-E2-DYW
Gene ID & Species: GRMZM2G456114 (Zea mays)
Edited Gene(s): nad7
Editing Type(s): C-to-U (6)
Publication(s): [1] DEK46 performs C-to-U editing of a specific site in mitochondrial nad7 introns that is critical for intron splicing and seed development in maize., The Plant journal : for cell and molecular biology, 2020. [PMID=32559332]

Editing Details

Species Gene ID Organelle Edited Gene Position Region Editing Type Codon Amino Acid Molecular Effect Experiment Details
Zea mays GRMZM2G456114 Mitochondrion nad7 NA Intron C-to-U NA=>NA NA=>NA NA
Experiment Details
Genotype (Ecotype) Allele Treatment Treatment Detail Mutant Type Phenotype Tissue Development Stage Detection Method Editing Frequency Editing Extent Mutant Effect PMID
W22WTWild TypeWild TypeNo mutantNormalKernel12 DAPRT‐PCR and sequencing93.50%HighNone32559332
W22dek46-1MutationDek46 contains one intron, in which a Mu element is inserted at +1471 bp (“A” of the start codon is assigned “+1”) in dek46‐1RecessiveThe dek46‐1 mutant showed a defective kernel phenotype, with small kernels and shrunken pericarps after maturation. The volume of starchy endosperm in the mutant kernels is significantly lower than that in the wild type. The embryo is small and does not possess a scutellum, shoot apex or primary root primordium after maturation.Kernel12 DAPRT‐PCR and sequencing0.00%UneditedAbsent32559332
W22dek46-2MutationDek46 contains one intron, in which a Mu element is inserted at +66 bp (“A” of the start codon is assigned “+1”) in dek46‐2Recessive; HeterozygousSelfed heterozygous dek46‐2 plants segregated with a dek phenotype similar to that of dek46‐1. The dek46‐1 mutant showed a defective kernel phenotype, with small kernels and shrunken pericarps after maturation. The volume of starchy endosperm in the mutant kernels is significantly lower than that in the wild type. The embryo is small and does not possess a scutellum, shoot apex or primary root primordium after maturation.Kernel12 DAPRT‐PCR and sequencing0.00%UneditedAbsent32559332
W22WTWild TypeWild TypeNo mutantNormalKernel12 DAPRT‐PCR and sequencing81.93%HighNone32559332
W22dek46-1MutationDek46 contains one intron, in which a Mu element is inserted at +1471 bp (“A” of the start codon is assigned “+1”) in dek46‐1RecessiveThe dek46‐1 mutant showed a defective kernel phenotype, with small kernels and shrunken pericarps after maturation. The volume of starchy endosperm in the mutant kernels is significantly lower than that in the wild type. The embryo is small and does not possess a scutellum, shoot apex or primary root primordium after maturation.Kernel12 DAPRT‐PCR and sequencing0.00%UneditedAbsent32559332
W22dek46-2MutationDek46 contains one intron, in which a Mu element is inserted at +66 bp (“A” of the start codon is assigned “+1”) in dek46‐2Recessive; HeterozygousSelfed heterozygous dek46‐2 plants segregated with a dek phenotype similar to that of dek46‐1. The dek46‐1 mutant showed a defective kernel phenotype, with small kernels and shrunken pericarps after maturation. The volume of starchy endosperm in the mutant kernels is significantly lower than that in the wild type. The embryo is small and does not possess a scutellum, shoot apex or primary root primordium after maturation.Kernel12 DAPRT‐PCR and sequencing0.00%UneditedAbsent32559332
Last update: Jul 2021 (version 1.0)