PED
Plant
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Database
MEF46 - Plant Editosome Database - CNCB-NGDC
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Summary

Editing Factor: MEF46
Synonym: MITOCHONDRIAL EDITING FACTOR 46
Description: Tetratricopeptide repeat (TPR)-like superfamily protein;(source:Araport11)
Protein Family: PPR
Subclass: E+
Physical Interaction: DYW2
Construct Structure: PLS-E1-E2-E+
Gene ID & Species: AT2G17210 (Arabidopsis thaliana)
Edited Gene(s): nad5
Editing Type(s): C-to-U (3)
Publication(s): [1] MEF46 and MEF47 are novel specificity factors for RNA editing sites in mitochondrial nad transcripts., Mitochondrion, 2020. [PMID=32439621]

Editing Details

Species Gene ID Organelle Edited Gene Position Region Nuclear Genome Organelle Genome Other Position Region Other Position Editing Type Codon Amino Acid Molecular Effect Experiment Details
Arabidopsis thaliana AT2G17210 Mitochondrion nad5 1958 CDS NA NA NA NA C-to-U NA=>NA NA=>NA NA
Experiment Details
Genotype (Ecotype) Allele Treatment Treatment Detail Mutant Type Phenotype Tissue Development Stage Detection Method Editing Frequency Editing Extent Mutant Effect PMID
ColumbiaCol-0ControlControlControlNormalLeaf3-week-old plantletsDirect cDNA sequencing and RT-PCR100.00%CompleteNone32439621
SALK_059706mef46-1A T-DNA InsertionLocation of the T-DNA insertions in the mutant and its respective left borders(LB) is at the second S motif from ATG.HomozygousThe mef46-1 line showed an overall normal growth phenotype comparable to the wild type plant under standard growth chamber conditions.Leaf3-week-old plantletsDirect cDNA sequencing and RT-PCR0.00%UneditedAbsent32439621
SALK_059706mef46-1+35S:MEF46(1)ComplementedLocation of the T-DNA insertions in the mutant and its respective left borders(LB) is at the second S motif from ATG. Overexpression of the MEF46 locus under the 35S promoter in the mef46-1 mutant linHomozygousNormalLeaf3-week-old plantletsDirect cDNA sequencing and RT-PCR100.00%CompleteRestored32439621
Last update: Feb 2026 (version 2.0)