Plant Editosome Database
a curated database of RNA editosome in plants

MEF46 - Plant Editosome Database - BIG Data Center
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Summary

Editing Factor: MEF46
Synonym: MITOCHONDRIAL EDITING FACTOR 46
Description: Tetratricopeptide repeat (TPR)-like superfamily protein;(source:Araport11)
Protein Family: PPR
Subclass: E+
Construct Structure: PLS-E1-E2-E+
Gene ID & Species: AT2G17210 (Arabidopsis thaliana)
Edited Gene(s): nad5
Editing Type(s): C-to-U (3)
Publication(s): [1] MEF46 and MEF47 are novel specificity factors for RNA editing sites in mitochondrial nad transcripts., Mitochondrion, 2020. [PMID=32439621]

Editing Details

Species Gene ID Organelle Edited Gene Position Region Editing Type Codon Amino Acid Molecular Effect Experiment Details
Arabidopsis thaliana AT2G17210 Mitochondrion nad5 1958 CDS C-to-U NA=>NA NA=>NA NA
Experiment Details
Genotype (Ecotype) Allele Treatment Treatment Detail Mutant Type Phenotype Tissue Development Stage Detection Method Editing Frequency Editing Extent Mutant Effect PMID
ColumbiaCol-0ControlControlControlNormalLeaf3-week-old plantletsDirect cDNA sequencing and RT-PCR100.00%CompleteNone32439621
SALK_059706mef46-1A T-DNA InsertionLocation of the T-DNA insertions in the mutant and its respective left borders(LB) is at the second S motif from ATG.HomozygousThe mef46-1 line showed an overall normal growth phenotype comparable to the wild type plant under standard growth chamber conditions.Leaf3-week-old plantletsDirect cDNA sequencing and RT-PCR0.00%UneditedAbsent32439621
SALK_059706mef46-1+35S:MEF46(1)ComplementedLocation of the T-DNA insertions in the mutant and its respective left borders(LB) is at the second S motif from ATG. Overexpression of the MEF46 locus under the 35S promoter in the mef46-1 mutant linHomozygousNormalLeaf3-week-old plantletsDirect cDNA sequencing and RT-PCR100.00%CompleteRestored32439621
Last update: Jul 2021 (version 1.0)