Plant
Editosome
Database
Summary
| Editing Factor: | MPR25 |
| Synonym: | MITOCHONDRIAL PPR 25 |
| Description: | MPR25 was preferentially expressed in leaves; FLAG-tagged MPR25 accumulated in mitochondria but not in chloroplasts. Direct sequencing revealed that the mpr25 mutant fails to edit a C-U RNA editing site at nucleotide 1580 of nad5, which encodes a subunit of complex I (NADH dehydrogenase) of the respiratory chain in mitochondria; NADH dehydrogenase activity of complex I was not affected in the mutant; By contrast, genes encoding alternative NADH dehydrogenases and alternative oxidase were up-regulated |
| Protein Family: | Pentatricopeptide repeat (PPR) protein |
| Subclass: | E+ |
| Physical Interaction: | NA |
| Construct Structure: | NA |
| Gene ID & Species: | NA (Arabidopsis thaliana) |
| Edited Gene(s): | nad5 |
| Editing Type(s): | C-to-U (3) |
| Publication(s): |
[1] Multiple PPR Protein Interactions Are Involved in the RNA Editing System in Arabidopsis Mitochondria and Plastids, Proc Natl Acad Sci U S A, 2017. [doi:10.1073/pnas.1705815114] |
Editing Details
| Species | Gene ID | Organelle | Edited Gene | Position | Region | Nuclear Genome | Organelle Genome | Other Region | Other Position | Editing Type | Codon | Amino Acid | Molecular Effect | Experiment Details | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Arabidopsis thaliana | NA | Mitochondrion | nad5 | 1580 | CDS | NA | NA | NA | NA | C-to-U | NA=>NA | NA=>NA | NA |
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Last update: Sep 2026
(version 2.0)