Plant
Editosome
Database
Summary
| Editing Factor: | SMK1 |
| Synonym: | Small Kernel 1 |
| Description: | Loss of SMK1 function abolishes the C-to-U editing at the nad7-836 site, leading to the retention of a proline codon that is edited to encode leucine in the wild type; The smk1 mutant showed dramatically reduced complex-I assembly and NADH dehydrogenase activity, and abnormal biogenesis of the mitochondria; Analysis of the ortholog in Oryza sativa (rice) reveals that rice SMK1 has a conserved function in C-to-U editing of the mitochondrial nad7-836 site; The leucine at NAD7-279 is highly conserved from bacteria to flowering plants, and analysis of genome sequences from many plants revealed a molecular coevolution between the requirement for C-to-U editing at this site and the existence of an SMK1 homolog |
| Protein Family: | Pentatricopeptide repeat (PPR) protein |
| Subclass: | E |
| Physical Interaction: | NA |
| Construct Structure: | PLS-E |
| Gene ID & Species: | LOC_OS11G10740 (Oryza sativa) |
| Edited Gene(s): | nad7 |
| Editing Type(s): | C-to-U (2) |
| Publication(s): |
[1] Small kernel 1 encodes a pentatricopeptide repeat protein required for mitochondrial nad7 transcript editing and seed development in maize (Zea mays) and rice (Oryza sativa), The Plant Journal, 2014. [doi:10.1111/tpj.12584] |
Editing Details
| Species | Gene ID | Organelle | Edited Gene | Position | Region | Nuclear Genome | Organelle Genome | Other Region | Other Position | Editing Type | Codon | Amino Acid | Molecular Effect | Experiment Details | |||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Oryza sativa | LOC_OS11G10740 | Mitochondrion | nad7 | 836 | CDS | NA | NA | NA | NA | C-to-U | CCU=>CUU | P=>L | Recoding |
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Last update: Sep 2026
(version 2.0)