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TAD2 - Plant Editosome Database - CNCB-NGDC
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Summary

Editing Factor: TAD2
Synonym: ATTAD2; EMB2191; EMBRYO DEFECTIVE 2191; TRNA ADENOSINE DEAMINASE 2
Description: Encoding a protein belonging to cytidine/deoxycytidylate deaminase family. Knockout of TAD2 is lethal and leads to arrested embryo development at the globular stage
Protein Family: Adenosine deaminase
Subclass: NA
Physical Interaction: TAD3
Construct Structure: NA
Gene ID & Species: AT1G48175 (Arabidopsis thaliana)
Edited Gene(s): tRNA-Ala(AGC)    tRNA-Ser(AGA)    tRNA-Leu(AAG)    tRNA-Ile(AAT)    tRNA-Arg(ACG)    tRNA-Thr(AGT)
Editing Type(s): A-to-I (12)
Publication(s): [1] Identification of enzymes for adenosine-to-inosine editing and discovery of cytidine-to-uridine editing in nucleus-encoded transfer RNAs of Arabidopsis., Plant physiology, 2014. [PMID=25315605]

Editing Details

Species Gene ID Organelle Edited Gene Position Region Nuclear Genome Organelle Genome Other Position Region Other Position Editing Type Codon Amino Acid Molecular Effect Experiment Details
Arabidopsis thaliana AT1G48175 Nucleus tRNA-Ala(AGC) 34 Exon TAIR NA NA NA A-to-I NA=>NA NA=>NA NA
Experiment Details
Genotype (Ecotype) Allele Treatment Treatment Detail Mutant Type Phenotype Tissue Development Stage Detection Method Editing Frequency Editing Extent Mutant Effect PMID
Col-0tad2-RNAi-BRNAiAgrobacterium tumefaciens-mediated transformationKnockdownA mild growth retardationLeafNADirect sequencing of PCR productsNAHighDecreased25315605
Col-0WTControlControlControlNormalLeafNADirect sequencing of PCR products100.00%CompleteNone25315605
Arabidopsis thaliana AT1G48175 Nucleus tRNA-Arg(ACG) 34 Exon TAIR NA NA NA A-to-I NA=>NA NA=>NA NA
Experiment Details
Genotype (Ecotype) Allele Treatment Treatment Detail Mutant Type Phenotype Tissue Development Stage Detection Method Editing Frequency Editing Extent Mutant Effect PMID
Col-0tad2-RNAi-BRNAiAgrobacterium tumefaciens-mediated transformationKnockdownA mild growth retardationLeafNADirect sequencing of PCR productsNAHighDecreased25315605
Col-0WTControlControlControlNormalLeafNADirect sequencing of PCR products100.00%CompleteNone25315605
Arabidopsis thaliana AT1G48175 Nucleus tRNA-Ile(AAT) 34 Exon TAIR NA NA NA A-to-I NA=>NA NA=>NA NA
Experiment Details
Genotype (Ecotype) Allele Treatment Treatment Detail Mutant Type Phenotype Tissue Development Stage Detection Method Editing Frequency Editing Extent Mutant Effect PMID
Col-0tad2-RNAi-BRNAiAgrobacterium tumefaciens-mediated transformationKnockdownA mild growth retardationLeafNADirect sequencing of PCR productsNALowDecreased25315605
Col-0WTControlControlControlNormalLeafNADirect sequencing of PCR productsNAMediumNone25315605
Arabidopsis thaliana AT1G48175 Nucleus tRNA-Leu(AAG) 34 Exon TAIR NA NA NA A-to-I NA=>NA NA=>NA NA
Experiment Details
Genotype (Ecotype) Allele Treatment Treatment Detail Mutant Type Phenotype Tissue Development Stage Detection Method Editing Frequency Editing Extent Mutant Effect PMID
Col-0tad2-RNAi-BRNAiAgrobacterium tumefaciens-mediated transformationKnockdownA mild growth retardationLeafNADirect sequencing of PCR productsNAMediumDecreased25315605
Col-0WTControlControlControlNormalLeafNADirect sequencing of PCR productsNAHighNone25315605
Arabidopsis thaliana AT1G48175 Nucleus tRNA-Ser(AGA) 34 Exon TAIR NA NA NA A-to-I NA=>NA NA=>NA NA
Experiment Details
Genotype (Ecotype) Allele Treatment Treatment Detail Mutant Type Phenotype Tissue Development Stage Detection Method Editing Frequency Editing Extent Mutant Effect PMID
Col-0tad2-RNAi-BRNAiAgrobacterium tumefaciens-mediated transformationKnockdownA mild growth retardationLeafNADirect sequencing of PCR productsNAMediumDecreased25315605
Col-0WTControlControlControlNormalLeafNADirect sequencing of PCR productsNAHighNone25315605
Arabidopsis thaliana AT1G48175 Nucleus tRNA-Thr(AGT) 34 Exon TAIR NA NA NA A-to-I NA=>NA NA=>NA NA
Experiment Details
Genotype (Ecotype) Allele Treatment Treatment Detail Mutant Type Phenotype Tissue Development Stage Detection Method Editing Frequency Editing Extent Mutant Effect PMID
Col-0tad2-RNAi-BRNAiAgrobacterium tumefaciens-mediated transformationKnockdownA mild growth retardationLeafNADirect sequencing of PCR productsNAHighDecreased25315605
Col-0WTControlControlControlNormalLeafNADirect sequencing of PCR products100.00%CompleteNone25315605
Last update: Feb 2026 (version 2.0)