Basic Metabolism Analysis

  • Metabolic flux balance loss
  • Covergency of the total loss and four loss terms during the training of neural networks.

  • Metabolic flux in 168 modules
  • A total of 168 metabolic modules were included in scFEA, the distribution of their calculated metabolic fluxes were visualized.

  • Metabolic flux in 34 pathways
  • A total of 34 metabolic pathways were manually curated from KEGG based on 168 metabolic modules, the distribution of their calculated metabolic fluxes were visualized.

KEGG pathway Module ID Compound IN name Compound IN ID Compound OUT name Compound OUT ID

Metabolic Comparative Analysis

  • Cell-type Log2FC of 168 modules
  • Cell-type Log2FC of 34 pathways
  • Glycolysis versus TCA cycle

Metabolic Correlation Analysis