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Editome Disease Knowledgebase
Editome-disease associations based on literature curation and integrative analysis

EDK
Editome Disease Knowledgebase

Home Diseases
Literature Curation
Genes Editing Sites Viruses Enzymes Publications
Integrative Analysis
Editing Datasets Differential Edited Genes Differential Editing Sites
Featured Annotation
cis-RNA Editing QTLs RNA Binding Proteins RNA Secondary Structure
Tools
Editing Site Identification Disease Prediction Gene-Disease Network Construction Cross-Disease Analysis Editing Site Annotation
Statistics Download
Help
FAQ Contact Us
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{{disease.name}}

{{disease.name}}

Basic Information Summary Literature Curation
Genes () Editing Sites () Enzymes () Viruses ()
Integrative Analysis
Editing Projects () Differential Edited Genes () Differential Editing Sites ()

{{disease.name}}

{{disease.description}}

Basic Information
DOID:{{disease.doid}}
Category:{{disease.category}}
Enzyme:
Tissue:
Editing Type:

Summary
Literature Curation
{{disease.name}} is associated with edited gene(s), including .
In {{disease.name}}, there are literature curated editing association(s), of which are supported by evidence at A-to-I RNA editing type and are supported at C-to-U RNA editing type.
It is reported that the aberrant of enzyme(s) is associated with {{disease.name}}.
It is reported that the RNA editing in virus(es) is associated with {{disease.name}}.
Integrative Analysis
there are {{disease.name}} related editing project(s) in the database, including .
Totally, there are differential editing sites in {{disease.name}}, of which are up-regulated sites and are down-regulated sites. These sites are distributed across differential edited genes.
In {{disease.name}}, the top ten genes that are most influenced by RNA editing contain .

Literature Curation
Genes ()
Edited Gene ID Gene Symbol Editing Type Enzyme Editing Level Correlation

Editing Sites ()

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Chromosome Position Edited Gene ID Gene Symbol Editing Type Codon Alteration Amino Acid Alteration Amino Acid Position Region Transcript Position Enzyme Strategy Disease Editing Level Correlation Molecular Effect Tissue Cell Type Treatment Survival PMID

Enzymes ()

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Enzyme Aberrance Disease Target Regulation Target Target Function Correlation Regulator Regulator Function Phenotype Description Cell Type Cell Line Strategy Treatment PMID

Viruses ()
Deamination-dependent Associations Between RNA Editing and Viruses-disease () Deamination-independent Associations Between Editing Enzyme and Viruses-disease ()

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Virus Virus Abbreviation Host Edited Gene Edited Gene Alias Editing Enzyme Editing Type Editing Site Disease Editing Level Molecular Effect Correlation Regulation Description PMID

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Virus Virus Abbreviation Host Editing Enzyme Disease Correlation Regulation Description PMID
Integrative Analysis
Editing Projects ()
Download Editing Dataset ID GEN Datatset ID Disease Title Strategy Tissue Cell Type Cell Line Sample Number

Differential Edited Genes ()
View Details Edited Gene ID Gene Symbol Disease #DES #A-to-I Up DES #A-to-I Down DES #C-to-U Up DES #C-to-U Down DES

Differential Editing Sites ()
Position Disease Editing Type Strand Edited Gene ID Gene Symbol Region Element Repeat Regulation P Value Fold Change