EDK Editome Disease Knowledgebase

  1. Home
  2. Publications

Publications

PMID Title Journal Year Target
24556721 RNA editome imbalance in hepatocellular carcinoma. Cancer Res 2014
23291631 Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma. Nat Med 2013
23748106 Hepatocellular carcinoma: transcriptome diversity regulated by RNA editing. Int J Biochem Cell Biol 2013
24302582 Adenosine-to-inosine RNA editing mediated by ADARs in esophageal squamous cell carcinoma. Cancer Res 2014
14985749 Glutamate receptors: RNA editing and death of motor neurons. Nature 2004
28167531 Adenosine Deaminase That Acts on RNA 3 (ADAR3) Binding to Glutamate Receptor Subunit B Pre-mRNA Inhibits RNA Editing in Glioblastoma. J Biol Chem 2017
14559151 Glutamate receptor RNA editing: a molecular analysis of GluR2, GluR5 and GluR6 in human brain tissues and in NT2 cells following in vitro neural differentiation. Brain Res Mol Brain Res 2003
24679603 Hippocampus-specific deficiency in RNA editing of GluA2 in Alzheimer's disease. Neurobiol Aging 2014
22266371 GluA2 AMPA glutamate receptor subunit exhibits codon 607 Q/R RNA editing in the lens. Biochem Biophys Res Commun 2012
19447293 Effects of antidepressants on GluR2 Q/R site-RNA editing in modified HeLa cell line. Neurosci Res 2009
16225946 Underediting of GluR2 mRNA, a neuronal death inducing molecular change in sporadic ALS, does not occur in motor neurons in ALS1 or SBMA. Neurosci Res 2006
14757529 Regulation of glutamate receptor RNA editing and ADAR mRNA expression in developing human normal and Down's syndrome brains. Brain Res Dev Brain Res 2004
11442354 RNA editing at the Q/R site for the glutamate receptor subunits GLUR2, GLUR5, and GLUR6 in hippocampus and temporal cortex from epileptic patients. Neurobiol Dis 2001
8616634 Editing for an AMPA receptor subunit RNA in prefrontal cortex and striatum in Alzheimer's disease, Huntington's disease and schizophrenia. Brain Res 1995
7523595 RNA editing of the glutamate receptor subunits GluR2 and GluR6 in human brain tissue. J Neurochem 1994
7529592 Differential RNA editing efficiency of AMPA receptor subunit GluR-2 in human brain. Neuroreport 1994
21110885 ADAR2-dependent RNA editing of GluR2 is involved in thiamine deficiency-induced alteration of calcium dynamics. Mol Neurodegener 2010
9450685 Characterization of RNA editing of the glutamate-receptor subunits GluR5 and GluR6 in granule cells during cerebellar development. Brain Res Mol Brain Res 1997
11414791 High abundance of GluR1 mRNA and reduced Q/R editing of GluR2 mRNA in individual NADPH-diaphorase neurons. Mol Cell Neurosci 2001
15093687 Altered RNA editing of serotonin 5-HT2C receptor induced by interferon: implications for depression associated with cytokine therapy. Brain Res Mol Brain Res 2004
28265714 A short history of the 5-HT2C receptor: from the choroid plexus to depression, obesity and addiction treatment. Psychopharmacology (Berl) 2017
18554725 RNA editing of the serotonin 5HT2C receptor and its effects on cell signalling, pharmacology and brain function. Pharmacol Ther 2008
18045717 Serotonin2C receptor mRNA editing in neuropathic pain model. Neurosci Res 2008
19036977 Dysregulated editing of serotonin 2C receptor mRNAs results in energy dissipation and loss of fat mass. J Neurosci 2008
17554622 Editing of AMPA and serotonin 2C receptors in individual central neurons, controlling wakefulness. Cell Mol Neurobiol 2007
26950265 Involvement of serotonin 2C receptor RNA editing in accumbal neuropeptide Y expression and behavioural despair. Eur J Neurosci 2016
14602721 RNA editing induces variation in desensitization and trafficking of 5-hydroxytryptamine 2c receptor isoforms. J Biol Chem 2004
25807502 APOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcripts. PLoS One 2015
8808692 Analysis of possible WT1 RNA processing in primary Wilms tumors. Oncogene 1996
27595325 Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation. Nat Med 2016
27907896 Harnessing human ADAR2 for RNA repair - Recoding a PINK1 mutation rescues mitophagy. Nucleic Acids Res 2017
20126463 Alternative splicing and extensive RNA editing of human TPH2 transcripts. PLoS One 2010
28035363 ADAR2 functions as a tumor suppressor via editing IGFBP7 in esophageal squamous cell carcinoma. Int J Oncol 2017
23543219 Insulin-like growth factor-binding protein-7 (IGFBP7) transcript: A-to-I editing events in normal and cancerous human keratinocytes. Arch Dermatol Res 2013
23324600 RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling. RNA Biol 2013
19908260 Human BLCAP transcript: new editing events in normal and cancerous tissues. Int J Cancer 2010
9012403 A potential role for NF1 mRNA editing in the pathogenesis of NF1 tumors. Am J Hum Genet 1997
26080435 PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3. Proc Natl Acad Sci U S A 2015
25499081 RNA over-editing of BLCAP contributes to hepatocarcinogenesis identified by whole-genome and transcriptome sequencing. Cancer Lett 2015
16404425 Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa. Br J Cancer 2006
20843408 Increased A-to-I RNA editing of the transcript for GABAA receptor subunit α3 during chick retinal development. Vis Neurosci 2010
11001933 RNA hyperediting and alternative splicing of hematopoietic cell phosphatase (PTPN6) gene in acute myeloid leukemia. Hum Mol Genet 2000
24663214 RNA editing in RHOQ promotes invasion potential in colorectal cancer. J Exp Med 2014
22525274 ADAR2-editing activity inhibits glioblastoma growth through the modulation of the CDC14B/Skp2/p21/p27 axis. Oncogene 2013
29203771 Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma. Nat Commun 2017
24386085 ADAR2-mediated editing of miR-214 and miR-122 precursor and antisense RNA transcripts in liver cancers. PLoS One 2013
25686251 Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis. Nat Cell Biol 2015
27292188 ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis. Cell Stem Cell 2016
23093778 Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells. J Clin Invest 2012
29386624 A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression. Nat Commun 2018
29267965 ADAR2/miR-589-3p axis controls glioblastoma cell migration/invasion. Nucleic Acids Res 2018
15039537 Hepatitis D virus RNA editing is inhibited by a GFP fusion protein containing a C-terminally deleted delta antigen. J Gen Virol 2004
12237434 Initiation of hepatitis delta virus (HDV) replication: HDV RNA encoding the large delta antigen cannot replicate. J Gen Virol 2002
11514728 Characterization of hepatitis D virus genotype III among Yucpa Indians in Venezuela. J Gen Virol 2001
9672172 Hepatitis delta genotypes in chronic delta infection in the northeast of Spain (Catalonia). J Hepatol 1998
9528763 Hepatitis delta virus RNA editing is highly specific for the amber/W site and is suppressed by hepatitis delta antigen. Mol Cell Biol 1998
19941396 Identification of cellular partners of Influenza A virus (H5N1) non-structural protein NS1 by yeast two-hybrid system. Acta Virol 2009
26989717 Construction and eukaryotic expression of recombinant large hepatitis delta antigen. Rep Biochem Mol Biol 2013
11870382 Varied assembly and RNA editing efficiencies between genotypes I and II hepatitis D virus and their implications. Hepatology 2002
26568914 Hepatitis delta virus: A fascinating and neglected pathogen. World J Virol 2015
25416632 Elucidating variations in the nucleotide sequence of Ebola virus associated with increasing pathogenicity. Genome Biol 2014
25838269 Ebola Virus GP Gene Polyadenylation Versus RNA Editing. J Infect Dis 2015
26299853 [Ebola hemorrhagic fever: Properties of the pathogen and development of vaccines and chemotherapeutic agents]. Mol Biol (Mosk) 2015
23341589 RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase. Proc Natl Acad Sci U S A 2013
23686695 Deletion of the D domain of the human parainfluenza virus type 3 (HPIV3) PD protein results in decreased viral RNA synthesis and beta interferon (IFN-β) expression. Virus Genes 2013
1310183 RNA editing in the phosphoprotein gene of the human parainfluenza virus type 3. Virology 1992
23923604 Cloning and expression analysis of multiple proteins encoding P gene of Newcastle disease virus. Indian J Exp Biol 2013
18490071 Genetic variability and mRNA editing frequencies of the phosphoprotein genes of wild-type measles viruses. Virus Res 2008
8725103 Synthesis of leader RNA and editing of P mRNA during transcription by rinderpest virus. Virus Res 1996
8277263 RNA editing in Newcastle disease virus. J Gen Virol 1993
17913828 RNA editing of the human herpesvirus 8 kaposin transcript eliminates its transforming activity and is induced during lytic replication. J Virol 2007
29956457 Lipopolysaccharide enhances ADAR2 which drives Hirschsprung's disease by impairing miR-142-3p biogenesis. J Cell Mol Med 2018
29996118 CDK13 RNA Over-Editing Mediated by ADAR1 Associates with Poor Prognosis of Hepatocellular Carcinoma Patients. Cell Physiol Biochem 2018
29592874 Decreased A-to-I RNA editing as a source of keratinocytes’ dsRNA in psoriasis RNA 2018
30087110 RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure EMBO J 2018
28411194 Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers. Genome Res. 2017
27494666 ADARs Edit MicroRNAs to Promote Leukemic Stem Cell Activity. Cell Stem Cell 2016
23403535 A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer's disease, dementia with lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls. J. Alzheimers Dis. 2013
29527417 Global analysis of A-to-I RNA editing reveals association with common disease variants. PeerJ 2018
25582055 Modulation of microRNA editing, expression and processing by ADAR2 deaminase in glioblastoma. Genome Biol. 2015
26640150 Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis. Oncogene 2016
23979837 Kainate receptor RNA editing is markedly altered by acute spinal cord injury. J. Mol. Neurosci. 2013
12080062 Two novel transcripts for human endothelin B receptor produced by RNA editing/alternative splicing from a single gene. J. Biol. Chem. 2002
21569822 Increased RNA editing in EAAT2 pre-mRNA from amyotrophic lateral sclerosis patients: involvement of a cryptic polyadenylation site. Neurosci. Lett. 2011
10487495 Familial hypercholesterolemia. Acceptor splice site (G-->C) mutation in intron 7 of the LDL-R gene: alternate RNA editing causes exon 8 skipping or a premature stop codon in exon 8. LDL-R(Honduras-1) [LDL-R1061(-1) G-->C]. Atherosclerosis 1999
27373511 ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer. Gastroenterology 2016
28188287 A-to-I RNA Editing Up-regulates Human Dihydrofolate Reductase in Breast Cancer. J. Biol. Chem. 2017
17369310 Editing modifies the GABA(A) receptor subunit alpha3. RNA 2007
28533408 RNA editing of drives early tumor invasion and metastasis in familial esophageal cancer. Proc. Natl. Acad. Sci. U.S.A. 2017
28743982 Oesophageal cancer: RNA editing of SLC22A3 mRNAs: causative relevance to familial ESCC? Nat Rev Gastroenterol Hepatol 2017
21620933 Exposure of neurons to excitotoxic levels of glutamate induces cleavage of the RNA editing enzyme, adenosine deaminase acting on RNA 2, and loss of GLUR2 editing. Neuroscience 2011
14645909 Chronic hepatitis delta virus infection with genotype IIb variant is correlated with progressive liver disease. J. Gen. Virol. 2003
26398702 Associations between activation-induced cytidine deaminase/apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like cytidine deaminase expression, hepatitis B virus (HBV) replication and HBV-associated liver disease (Review). Mol Med Rep 2015
20701360 Quantitative proteomics using SILAC coupled to LC-MS/MS reveals changes in the nucleolar proteome in influenza A virus-infected cells. J. Proteome Res. 2010
25272020 Adenosine deaminase acting on RNA-1 (ADAR1) inhibits HIV-1 replication in human alveolar macrophages. PLoS ONE 2014
29906476 ADAR1 affects HCV infection by modulating innate immune response. Antiviral Res. 2018
26440892 Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome. Cell Rep 2015
24928581 ADAR1: a promising new biomarker for esophageal squamous cell carcinoma? Expert Rev Anticancer Ther 2014
21729523 [Expression of ADAR1 isoforms in murine acute T-ALL leukemia model]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 2011
21316340 Abnormal expression of ADAR1 isoforms in Chinese pediatric acute leukemias. Biochem. Biophys. Res. Commun. 2011
22684365 Driving transcriptional regulators in melanoma metastasis. Cancer Metastasis Rev. 2012
28199207 Assessing the potential function of ADAR1 in virus-associated sepsis. Front Biosci (Landmark Ed) 2017
23275297 ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. Proc. Natl. Acad. Sci. U.S.A. 2013
26338962 A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme. Oncotarget 2015
27911851 Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration. Oncotarget 2016
23001123 Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature. Nat. Genet. 2012
25172485 Adenosine deaminase acting on RNA 1 limits RIG-I RNA detection and suppresses IFN production responding to viral and endogenous RNAs. J. Immunol. 2014
25456137 The RNA-editing enzyme ADAR1 controls innate immune responses to RNA. Cell Rep 2014
16917490 Ten novel mutations of the ADAR1 gene in Japanese patients with dyschromatosis symmetrica hereditaria. J. Invest. Dermatol. 2007
19651874 Editing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infection. Nucleic Acids Res. 2009
19710021 RNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKR. J. Biol. Chem. 2009
24905200 An RNA editor, adenosine deaminase acting on double-stranded RNA (ADAR1). J. Interferon Cytokine Res. 2014
17079286 Double-stranded RNA deaminase ADAR1 increases host susceptibility to virus infection. J. Virol. 2007
25389016 ADAR1 enhances HTLV-1 and HTLV-2 replication through inhibition of PKR activity. Retrovirology 2014
23697632 ADAR2 editing activity in newly diagnosed versus relapsed pediatric high-grade astrocytomas. BMC Cancer 2013
20372915 TDP-43 pathology in sporadic ALS occurs in motor neurons lacking the RNA editing enzyme ADAR2. Acta Neuropathol. 2010
16183555 Excitotoxicity and ALS: what is unique about the AMPA receptors expressed on spinal motor neurons? Amyotroph. Lateral Scler. Other Motor Neuron Disord. 2005
24608178 Down-regulation of the RNA editing enzyme ADAR2 contributes to RGC death in a mouse model of glaucoma. PLoS ONE 2014
20637757 Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer. Gastroenterology 2010
18306229 Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma. Hepatology 2008
9633945 Low expression of the apolipoprotein B mRNA-editing transgene in mice reduces LDL levels but does not cause liver dysplasia or tumors. Arterioscler. Thromb. Vasc. Biol. 1998
11116209 Effects of a thyromimetic on apolipoprotein B-100 in rats. J. Mol. Endocrinol. 2000
9672068 Distinct promoters induce APOBEC-1 expression in rat liver and intestine. Arterioscler. Thromb. Vasc. Biol. 1998
26051357 High APOBEC3B expression is a predictor of recurrence in patients with low-risk clear cell renal cell carcinoma. Urol. Oncol. 2015
29769310 Tumor-associated intronic editing of HNRPLL generates a novel splicing variant linked to cell proliferation 2018
30770787 Brain region-specific alterations of RNA editing in PDE8A mRNA in suicide decedents 2019
30760294 Dynamic inosinome profiles reveal novel patient stratification and gender-specific differences in glioblastoma 2019
18462347 Altered editing in cyclic nucleotide phosphodiesterase 8A1 gene transcripts of systemic lupus erythematosus T lymphocytes 2008
28542129 ADAR1-mediated 3' UTR editing and expression control of antiapoptosis genes fine-tunes cellular apoptosis response. 2017
30290838 ADAR1-mediated RNA-editing of 3'UTRs in breast cancer 2018
28928239 The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK. 2017
29925690 AZIN1 RNA editing confers cancer stemness and enhances oncogenic potential in colorectal cancer 2018
30563560 Enhanced AZIN1 RNA editing and overexpression of its regulatory enzyme ADAR1 are important prognostic biomarkers in gastric cancer 2018
30583079 Activation of AZIN1 RNA editing is a novel mechanism that promotes invasive potential of cancer-associated fibroblasts in colorectal cancer 2019
30697154 Ethanol Preference and Drinking Behavior Are Controlled by RNA Editing in the Nucleus Accumbens 2019
17376196 Altered editing in RNA editing adenosine deaminase ADAR2 gene transcripts of systemic lupus erythematosus T lymphocytes 2007
29617672 Increased RNA Editing May Provide a Source for Autoantigens in Systemic Lupus Erythematosus 2018
12243919 Transcript mutations of the alpha regulatory subunit of protein kinase A and up-regulation of the RNA-editing gene transcript in lupus T lymphocytes 2002
30945056 ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD 2019
24401644 Differential impact of APOBEC3-driven mutagenesis on HIV evolution in diverse anatomical compartments. AIDS 2014
17967058 Target cell APOBEC3C can induce limited G-to-A mutation in HIV-1. PLoS Pathog. 2007
25847768 Development of benzimidazole derivatives to inhibit HIV-1 replication through protecting APOBEC3G protein. Eur J Med Chem 2015
25330844 Circulating type 1 vaccine-derived poliovirus may evolve under the pressure of adenosine deaminases acting on RNA. J. Matern. Fetal. Neonatal. Med. 2015
25080100 Human APOBEC3 induced mutation of human immunodeficiency virus type-1 contributes to adaptation and evolution in natural infection. PLoS Pathog. 2014
24198285 GANP interacts with APOBEC3G and facilitates its encapsidation into the virions to reduce HIV-1 infectivity. J. Immunol. 2013
22695298 E138K and M184I mutations in HIV-1 reverse transcriptase coemerge as a result of APOBEC3 editing in the absence of drug exposure. AIDS 2012
22301159 The cellular antiviral protein APOBEC3G interacts with HIV-1 reverse transcriptase and inhibits its function during viral replication. J. Virol. 2012
22145963 APOBEC3-mediated editing in HIV type 1 from pediatric patients and its association with APOBEC3G/CUL5 polymorphisms and Vif variability. AIDS Res. Hum. Retroviruses 2012
21763507 Multifaceted counter-APOBEC3G mechanisms employed by HIV-1 Vif. J. Mol. Biol. 2011
21289159 ADAR2 editing enzyme is a novel human immunodeficiency virus-1 proviral factor. J. Gen. Virol. 2011
21167246 APOBEC3H haplotypes and HIV-1 pro-viral vif DNA sequence diversity in early untreated human immunodeficiency virus-1 infection. Hum. Immunol. 2011
20844042 The HIV-1 central polypurine tract functions as a second line of defense against APOBEC3G/F. J. Virol. 2010
20038599 The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cells. J. Exp. Med. 2010
19996938 APOBEC3G expression is dysregulated in primary HIV-1 infection and polymorphic variants influence CD4+ T-cell counts and plasma viral load. AIDS 2010
27890786 Heat Increases the Editing Efficiency of Human Papillomavirus E2 Gene by Inducing Upregulation of APOBEC3A and 3G. J. Invest. Dermatol. 2017
31337330 A-to-I editing of Malacoherpesviridae RNAs supports the antiviral role of ADAR1 in mollusks. BMC Evol. Biol. 2019
29100527 HPV11 E6 mutation by overexpression of APOBEC3A and effects of interferon-ω on APOBEC3s and HPV11 E6 expression in HPV11.HaCaT cells. Virol. J. 2017
27383210 Double-stranded-RNA-specific adenosine deaminase 1 (ADAR1) is proposed to contribute to the adaptation of equine infectious anemia virus from horses to donkeys. Arch. Virol. 2016
1846805 The P gene of bovine parainfluenza virus 3 expresses all three reading frames from a single mRNA editing site. EMBO J. 1991
9934693 RNA editing-like phenomenon in paramyxovirus V gene mRNA observed in insect cells infected with a recombinant baculovirus. J. Gen. Virol. 1999
2167560 Sequence analysis of the phosphoprotein (P) genes of human parainfluenza type 4A and 4B viruses and RNA editing at transcript of the P genes: the number of G residues added is imprecise. Virology 1990
30496178 Extensive editing of cellular and viral double-stranded RNA structures accounts for innate immunity suppression and the proviral activity of ADAR1p150. PLoS Biol. 2018
9018130 Recombinant measles viruses defective for RNA editing and V protein synthesis are viable in cultured cells. Virology 1997
7886959 Hypermutation of the phosphoprotein and altered mRNA editing in the hamster neurotropic strain of measles virus. Virology 1995
1895388 Synthesis of leader RNA and editing of the P mRNA during transcription by purified measles virus. J. Virol. 1991
31106880 Explaining Pathogenicity of Congenital Zika and Guillain-Barré Syndromes: Does Dysregulation of RNA Editing Play a Role? Bioessays 2019
28275585 Mutational Pressure in Zika Virus: Local ADAR-Editing Areas Associated with Pauses in Translation and Replication. Front Cell Infect Microbiol 2017
7494266 Hepatitis D virus RNA editing: specific modification of adenosine in the antigenomic RNA. J. Virol. 1995
31614652 Structural Pattern Differences in Unbranched Rod-like RNA of Hepatitis Delta Virus affect RNA Editing. Viruses 2019
16475990 The large form of ADAR 1 is responsible for enhanced hepatitis delta virus RNA editing in interferon-alpha-stimulated host cells. J. Viral Hepat. 2006
12399548 Replicating hepatitis delta virus RNA is edited in the nucleus by the small form of ADAR1. Proc. Natl. Acad. Sci. U.S.A. 2002
21732238 Control of ADAR1 editing of hepatitis delta virus RNAs. Curr. Top. Microbiol. Immunol. 2012
19383766 The fraction of RNA that folds into the correct branched secondary structure determines hepatitis delta virus type 3 RNA editing levels. RNA 2009
15254184 By inhibiting replication, the large hepatitis delta antigen can indirectly regulate amber/W editing and its own expression. J. Virol. 2004
12097551 RNA editing in hepatitis delta virus genotype III requires a branched double-hairpin RNA structure. J. Virol. 2002
11507200 Hepatitis delta virus minimal substrates competent for editing by ADAR1 and ADAR2. J. Virol. 2001
28988126 Quantitative characterization of hepatitis delta virus genome edition by next-generation sequencing. Virus Res. 2018
7474144 Hepatitis delta virus mutant: effect on RNA editing. J. Virol. 1995
8830113 Base changes at positions 1014 and 578 of delta virus RNA in Greek isolates maintain base pair in rod conformation with efficient RNA editing. J. Med. Virol. 1995
7748956 Requirements for editing in the genomic RNA of hepatitis delta virus. Biochimie 1994
1496009 Structural requirements for RNA editing in hepatitis delta virus: evidence for a uridine-to-cytidine editing mechanism. Proc. Natl. Acad. Sci. U.S.A. 1992
7853505 Nucleotide sequence stability of the genome of hepatitis delta virus. J. Virol. 1995
29129707 APOBEC3B edits HBV DNA and inhibits HBV replication during reverse transcription. Antiviral Res. 2018
29491156 Asymmetric Modification of Hepatitis B Virus (HBV) Genomes by an Endogenous Cytidine Deaminase inside HBV Cores Informs a Model of Reverse Transcription. J. Virol. 2018
31585913 ADAR1 promotes HBV replication through its deaminase domain. Front Biosci (Landmark Ed) 2020
18420796 Hypermutation of hepatitis B virus genomes by APOBEC3G, APOBEC3C and APOBEC3H. J. Gen. Virol. 2008
23853584 The interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replication. PLoS Pathog. 2013
22993189 Hyperediting of human T-cell leukemia virus type 2 and simian T-cell leukemia virus type 3 by the dsRNA adenosine deaminase ADAR-1. J. Gen. Virol. 2012
22457529 APOBEC3A, APOBEC3B, and APOBEC3H haplotype 2 restrict human T-lymphotropic virus type 1. J. Virol. 2012
17020943 A-to-G hypermutation in the genome of lymphocytic choriomeningitis virus. J. Virol. 2007
24045110 Perturbation of biogenesis and targeting of Epstein-Barr virus-encoded miR-BART3 microRNA by adenosine-to-inosine editing. J. Gen. Virol. 2013
26982470 Kinetic analysis of RNA editing of Newcastle disease virus P gene in the early period of infection. Acta Virol. 2016
10989186 Newcastle disease virus phosphoprotein gene analysis and transcriptional editing in avian cells. Virus Res. 2000
2166809 RNA editing by G-nucleotide insertion in mumps virus P-gene mRNA transcripts. J. Virol. 1990
2165137 Strain-variable editing during transcription of the P gene of mumps virus may lead to the generation of non-structural proteins NS1 (V) and NS2. J. Gen. Virol. 1990
8492098 Sequence determination of the P gene of simian virus 41: presence of irregular deletions near the RNA-editing sites of paramyxoviruses. J. Gen. Virol. 1993
26703716 Ebola Virus Infections in Nonhuman Primates Are Temporally Influenced by Glycoprotein Poly-U Editing Site Populations in the Exposure Material. Viruses 2015
26138826 RNA Editing of the GP Gene of Ebola Virus is an Important Pathogenicity Factor. J. Infect. Dis. 2015
21987773 Genomic RNA editing and its impact on Ebola virus adaptation during serial passages in cell culture and infection of guinea pigs. J. Infect. Dis. 2011
21411529 A new Ebola virus nonstructural glycoprotein expressed through RNA editing. J. Virol. 2011
8553543 GP mRNA of Ebola virus is edited by the Ebola virus polymerase and by T7 and vaccinia virus polymerases. Virology 1995
24146620 Ebola virus RNA editing depends on the primary editing site sequence and an upstream secondary structure. PLoS Pathog. 2013
25370495 Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells. mBio 2014
30045985 Strategy of Human Cytomegalovirus To Escape Interferon Beta-Induced APOBEC3G Editing Activity. J. Virol. 2018
8847510 The phosphoprotein gene of a dolphin morbillivirus isolate exhibits genomic variation at the editing site. J. Gen. Virol. 1995
16501082 Feline lentivirus evolution in cross-species infection reveals extensive G-to-A mutation and selection on key residues in the viral polymerase. J. Virol. 2006
29610985 Human-APOBEC3G-dependent restriction of porcine endogenous retrovirus replication is mediated by cytidine deamination and inhibition of DNA strand transfer during reverse transcription. Arch. Virol. 2018
12202220 Mutational analysis of the Sendai virus V protein: importance of the conserved residues for Zn binding, virus pathogenesis, and efficient RNA editing. Virology 2002
9847338 Two nucleotides immediately upstream of the essential A6G3 slippery sequence modulate the pattern of G insertions during Sendai virus mRNA editing. J. Virol. 1999
1688384 Editing of the Sendai virus P/C mRNA by G insertion occurs during mRNA synthesis via a virus-encoded activity. J. Virol. 1990
7957115 Paramyxovirus mRNA editing leads to G deletions as well as insertions. EMBO J. 1994
31939152 Regulation of Antiviral Innate Immunity Through APOBEC Ribonucleoprotein Complexes. Subcell. Biochem. 2019
18836454 Phosphorylation of APOBEC3G by protein kinase A regulates its interaction with HIV-1 Vif. Nat. Struct. Mol. Biol. 2008
26363218 The ADAR1 editing enzyme is encapsidated into HIV-1 virions. Virology 2015
23707381 A naturally occurring Vif mutant (I107T) attenuates anti-APOBEC3G activity and HIV-1 replication. J. Mol. Biol. 2013
23576497 APOBEC3G impairs the multimerization of the HIV-1 Vif protein in living cells. J. Virol. 2013
23427247 IFN-α induces APOBEC3G, F, and A in immature dendritic cells and limits HIV-1 spread to CD4+ T cells. J. Immunol. 2013
23001005 The APOBEC3C crystal structure and the interface for HIV-1 Vif binding. Nat. Struct. Mol. Biol. 2012
22044427 B-cell agonists up-regulate AID and APOBEC3G deaminases, which induce IgA and IgG class antibodies and anti-viral function. Immunology 2012
21710755 [Research methods of anti-HIV-1 inhibitors targeting at Vif-APOBEC3G axis]. Zhongguo Zhong Yao Za Zhi 2011
31397674 USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication. Elife 2019
30670656 Apobec3A maintains HIV-1 latency through recruitment of epigenetic silencing machinery to the long terminal repeat. Proc. Natl. Acad. Sci. U.S.A. 2019
30135687 APOBEC3G/3A Expression in Human Immunodeficiency Virus Type 1-Infected Individuals Following Initiation of Antiretroviral Therapy Containing Cenicriviroc or Efavirenz. Front Immunol 2018
26629815 ADAR1 Facilitates HIV-1 Replication in Primary CD4+ T Cells. PLoS ONE 2015
29290613 The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism. Mol. Cell 2018
29258557 Moloney leukemia virus 10 (MOV10) inhibits the degradation of APOBEC3G through interference with the Vif-mediated ubiquitin-proteasome pathway. Retrovirology 2017
12808465 The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. Nature 2003
12808466 Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. Nature 2003
12914693 Death by deamination: a novel host restriction system for HIV-1. Cell 2003
12970355 The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity. J. Biol. Chem. 2003
14528300 The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif. Nat. Med. 2003
14528301 HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation. Nat. Med. 2003
14978281 A single amino acid of APOBEC3G controls its species-specific interaction with virion infectivity factor (Vif). Proc. Natl. Acad. Sci. U.S.A. 2004
15286366 APOBEC-mediated editing of viral RNA. Science 2004
15611076 HIV-1 Vif can directly inhibit apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G-mediated cytidine deamination by using a single amino acid interaction and without protein degradation. J. Biol. Chem. 2005
15668174 Antiviral function of APOBEC3G can be dissociated from cytidine deaminase activity. Curr. Biol. 2005
17121840 APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G. J. Biol. Chem. 2007
17459442 Inhibition of initiation of reverse transcription in HIV-1 by human APOBEC3F. Virology 2007
17855362 APOBEC3G inhibits DNA strand transfer during HIV-1 reverse transcription. J. Biol. Chem. 2007
18067920 Interaction with 7SL RNA but not with HIV-1 genomic RNA or P bodies is required for APOBEC3F virion packaging. J. Mol. Biol. 2008
20178977 Interaction of Vpx and apolipoprotein B mRNA-editing catalytic polypeptide 3 family member A (APOBEC3A) correlates with efficient lentivirus infection of monocytes. J. Biol. Chem. 2010
30859472 Polymorphisms in the APOBEC3G gene of Chinese rhesus macaques affect resistance to ubiquitination and degradation mediated by HIV-2 Vif. Arch. Virol. 2019
21775448 APOBEC1-mediated editing and attenuation of herpes simplex virus 1 DNA indicate that neurons have an antiviral role during herpes simplex encephalitis. J. Virol. 2011
25589239 Double-stranded RNA-specific adenosine deaminase 1 (ADAR1) promotes EIAV replication and infectivity. Virology 2015
22170635 The innate antiviral factor APOBEC3G targets replication of measles, mumps and respiratory syncytial viruses. J. Gen. Virol. 2012
28649357 RNA editing by the host ADAR system affects the molecular evolution of the Zika virus. Ecol Evol 2017
31636123 Double-stranded RNA deaminase ADAR1 promotes the Zika virus replication by inhibiting the activation of protein kinase PKR. J. Biol. Chem. 2019
30862444 APOBEC3G is a restriction factor of EV71 and mediator of IMB-Z antiviral activity. Antiviral Res. 2019
21173229 RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis. Proc. Natl. Acad. Sci. U.S.A. 2011
31519749 Zika virus noncoding sfRNAs sequester multiple host-derived RNA-binding proteins and modulate mRNA decay and splicing during infection. J. Biol. Chem. 2019
16729314 Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication. Hepatology 2006
17167839 N-terminal and C-terminal cytosine deaminase domain of APOBEC3G inhibit hepatitis B virus replication. World J. Gastroenterol. 2006
17314171 Deamination-independent inhibition of hepatitis B virus reverse transcription by APOBEC3G. J. Virol. 2007
17625792 Hepatitis B virus DNA is subject to extensive editing by the human deaminase APOBEC3C. Hepatology 2007
18597676 Characterization of APOBEC3G binding to 7SL RNA. Retrovirology 2008
32056513 DHX9 interacts with APOBEC3B and attenuates the anti-HBV effect of APOBEC3B. Emerg Microbes Infect 2020
29550589 Nonlytic Lymphocytes Engineered to Express Virus-Specific T-Cell Receptors Limit HBV Infection by Activating APOBEC3. Gastroenterology 2018
28098260 Hepatitis B virus X protein is capable of down-regulating protein level of host antiviral protein APOBEC3G. Sci Rep 2017
15858013 New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1. J. Virol. 2005
17036163 High expression of APOBEC3G in patients infected with hepatitis C virus. J. Mol. Histol. 2006
21480314 Host apolipoprotein B messenger RNA-editing enzyme catalytic polypeptide-like 3G is an innate defensive factor and drug target against hepatitis C virus. Hepatology 2011
28018102 Apolipoprotein B100 is required for hepatitis C infectivity and Mipomersen inhibits hepatitis C. World J. Gastroenterol. 2016
21994604 RNA editing and its control in hepatitis delta virus replication. Viruses 2010
30420783 Epstein-Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity. Nat Microbiol 2019
27147740 Functional Upregulation of the DNA Cytosine Deaminase APOBEC3B by Polyomaviruses. J. Virol. 2016
28331087 Feline Immunodeficiency Virus Evolutionarily Acquires Two Proteins, Vif and Protease, Capable of Antagonizing Feline APOBEC3. J. Virol. 2017
26935128 Species-specific differences in the ability of feline lentiviral Vif to degrade feline APOBEC3 proteins. Microbiol. Immunol. 2016
25576866 APOBEC3A and 3C decrease human papillomavirus 16 pseudovirion infectivity. Biochem. Biophys. Res. Commun. 2015
29593034 Deaminase-Dead Mouse APOBEC3 Is an Retroviral Restriction Factor. J. Virol. 2018
23671100 Murine leukemia virus glycosylated Gag blocks apolipoprotein B editing complex 3 and cytosolic sensor access to the reverse transcription complex. Proc. Natl. Acad. Sci. U.S.A. 2013
23449789 APOBEC3 inhibition of mouse mammary tumor virus infection: the role of cytidine deamination versus inhibition of reverse transcription. J. Virol. 2013
27193350 Small ruminant lentiviral Vif proteins commonly utilize cyclophilin A, an evolutionarily and structurally conserved protein, to degrade ovine and caprine APOBEC3 proteins. Microbiol. Immunol. 2016
29149056 Characterization of Ovine A3Z1 Restriction Properties against Small Ruminant Lentiviruses (SRLVs). Viruses 2017