LOCUS C_AAB29187 4402 aa linear VRL 11-MAY-2023 DEFINITION ORF1a polyprotein [Severe acute respiratory syndrome coronavirus 2]. ACCESSION C_AAB29187 VERSION C_AAB29187.1 KEYWORDS . SOURCE Severe acute respiratory syndrome coronavirus 2 ORGANISM Severe acute respiratory syndrome coronavirus 2 Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; Sarbecovirus; Severe acute respiratory syndrome-related coronavirus. DBSOURCE accession C_AA014193.1 REFERENCE 1 (residues 1 to 4402) AUTHORS Zhang,W. TITLE Direct Submission JOURNAL Submitted (11-MAY-2023) Microbe lab, Shanghai Municipal Center for Disease Control & Prevention, west zhongshan road 1380, Shanghai 200336, China COMMENT ##Genome-Assembly-Data-START## Assembly Method :: Consensus sequence method v. 940-000133-00 Sequencing Technology :: MGISEQ-200 ##Genome-Assembly-Data-END## Method: conceptual translation. FEATURES Location/Qualifiers source 1..4402 /organism="Severe acute respiratory syndrome coronavirus 2" /isolate="SARS-CoV-2/human/CHN/SH-HG20230504-505/2023" /isolation_source="Pharyngeal swab" /host="Homo sapiens; Host_age: 42; Host_sex: unknown" /country="China:Shanghai" /collection_date="2023-05-02" /note="Passage_details/history: Original; Additional_host_information: Patient infected while traveling in Singapore" Protein 1..4402 /product="ORF1a polyprotein" mat_peptide 1..180 /product="leader protein" mat_peptide 181..818 /product="nsp2" mat_peptide 819..2763 /product="nsp3" mat_peptide 2764..3263 /product="nsp4" mat_peptide 3264..3569 /product="3C-like proteinase" mat_peptide 3570..3856 /product="nsp6" mat_peptide 3857..3939 /product="nsp7" mat_peptide 3940..4137 /product="nsp8" mat_peptide 4138..4250 /product="nsp9" mat_peptide 4251..4389 /product="nsp10" mat_peptide 4390..4402 /product="nsp11" CDS 1..4402 /gene="ORF1ab" /coded_by="C_AA014193.1:242..13450" ORIGIN 1 meslvpgfne kthvqlslpv lqvrdvlvrg fgdsveevls earqhlrdgt cglvevekgv 61 lpqleqpyvf ikrsdartap hghvmvelva elegiqygrs getlgvlvph vgeipvayrk 121 vllrkngnkg agghrygadl ksfdlgdelg tdpyedfqen wntkhssgvt relmrelngg 181 aytryvdnnf cgpdgyplec ikdllaragk asctlseqld fidtkrgvyc creheheiaw 241 yterseksye lqtpfeikla kkfdtfngec pnfvfplnsi iktiqprvek kkldgfmgri 301 rsvypvaspn ecnqmclstl mkcdhcgets wqtgdfvkat cefcgtenlt kegattcgyl 361 pqnavvkiyc pachnsevgp ehslaeyhne sglktilrkg grtiafggcv fsyvgchnkc 421 aywvprasan igcnhtgvvg egseglndnl leilqkekvn inivgdfkln eeiaiilasf 481 sastsafvet vkgldykafk qivescgnfk vtkgkakkga wnigeqksil splyafasea 541 arvvrsifsr tletaqnsvr vlqkaaitil dgisqyslrl idammftsdl atnnlvvmay 601 itggvvqlts qwltnifgtv yeklkpvldw leekfkegve flrdgweivk fistcaceiv 661 ggqivtcake ikesvqtffk lvnkflalca dsiiiggakl kalnlgetfv thskglyrkc 721 vksreetgll mplkapkeii flegetlpte vlteevvlkt gdlqpleqpt seaveaplvg 781 tpvcinglml leikdtekyc alapnmmvtn ntftlkggap tkvtfgddtv ievqgyksvn 841 iifelderid kvlnekcsay tvelgtevne facvvadavi ktlqpvsell tplgidldew 901 smatyylfde sgefklashm ycsfyppded eeegdceeee fepstqyeyg teddyqgkpl 961 efgatsaalq peeeqeedwl dddsqqtvgq qdgsednqtt tiqiivevqp qlemeltpvv 1021 qtievnsfsg ylkltdnvyi knadiveeak kvkptvvvna anvylkhggg vagalnkatn 1081 namqvesddy iatngplkvg gscvlsghnl akhclhvvgp nvnkgediql lksayenfnq 1141 hevllaplls agifgadpih slrvcvdtvr tnvylavfdk nlydklvssf lemksekqve 1201 qkiaeipkee vkpfiteskp sveqrkqddk kikacveevt ttleetkflt enlllyidin 1261 gnlhpdsatl vsdiditflk kdapyivgdv vqegvltavv iptkkasgtt emlakalrkv 1321 ptdnyittyp gqglngytve eaktvlkkck safyilpsii snekqeilgt vswnlremla 1381 haeetrklmp vcvetkaivs tiqrkykgik iqegvvdyga rfyfytsktt vaslintlnd 1441 lnetlvtmpl gyvthglnle eaarymrslk vpatvsvssp davtayngyl tsssktpeeh 1501 fietislags ykdwsysgqs tqlgieflkr gdksvyytsn pttfhldgev itfdnlktll 1561 slrevrtikv fttvdninlh tqvvdmsmty gqqfgptyld gadvtkikph nshegktfyv 1621 lpnddtlrve afeyyhttdp sflgrymsal nhtkkwkypq vngltsikwa dnncylatal 1681 ltlqqielkf nppalqdayy rarageaanf calilaycnk tvgelgdvre tmsylfqhan 1741 ldsckrvlnv vcktcgqqqt tlkgveavmy mgtlsyeqfk kgvqipctcg kqatkylvqq 1801 espfvmmsap paqyelkhgt ftcaseytgn yqcghykhit sketlycidg alltksseyk 1861 gpitdvfyke nsytttikpv tykldgvvct eidpkldnyy kkdnsyfteq pidlvpnqpy 1921 pnasfdnfkf vcdnikfadd lnqltgykkp asrelkvtff pdlngdvvai dykhytpsfk 1981 kgakllhkpi vwhvnnatnk atykpntwci rclwstkpve tsnsfdvlks edaqgmdnla 2041 cedlkpvsee vvenptiqkd vlecnvktte vvgdiilkpa nnslkiteev ghtdlmaayv 2101 dnssltikkp nelsrvlglk tlathglaav nsvpwdtian yakpflnkvv stttnivtrc 2161 lnrvctnymp yfftlllqlc tftrstnsri kasmpttiak ntvksvgkfc leasfnylks 2221 pnfsklinii iwflllsvcl gsliystaal gvlmsnlgmp syctgyregy lnstnvtiat 2281 yctgsipcsv clsgldsldt ypsletiqit issfkwdlta fglvaewfla yilftrffyv 2341 lglaaimqlf fsyfavhfis nswlmwliin lvqmapisam vrmyiffasf yyvwksyvhv 2401 vdgcnsstcm mcykrnratr vecttivngv rrsfyvyang gkgfcklhnw ncvncdtfca 2461 gstfisdeva rdlslqfkrp inptdqssyi vdsvtvkngs ihlyfdkagq ktyerhslsh 2521 fvnldnlran ntkgslpinv ivfdgkskce essaksasvy ysqlmcqpil lldqalvsdv 2581 gdsaevavkm fdayvntfss tfnvpmeklk tlvataeael aknvsldnvl stfisaarqg 2641 fvdsdvetkd vveclklshq sdievtgdsc nnymltynkv enmtprdlga cidcsarhin 2701 aqvakshnia liwnvkdfms lseqlrkqir saakknnlpf kltcattrqv vnvvttkial 2761 kggkivnnwl kqlikvtlvf lfvaaifyli tpvhvmskht dfsseiigyk aidggvtrdi 2821 astdtcfank hadfdtwfsq rggsytndka cpliaavitr evgfvvpglp gtilrttngd 2881 flhflprvfs avgnicytps klieytdfat sacvlaaect ifkdasgkpv pycydtnvle 2941 gsvayeslrp dtryvlmdgs iiqfpntyle gsvrvvttfd seycrhgtce rseagvcvst 3001 sgrwvlnndy yrslpgvfcg vdavnlftnm ftpliqpiga ldisasivag givaivvtcl 3061 ayyfmrfrra fgeyshvvaf ntllflmsfi vlcltpvysf lpgvysviyl yltfyltndv 3121 sflahiqwmv mftplvpfwi tiayiicist khfywffsny lkrrvvfngv sfstfeeaal 3181 ctfllnkemy lklrsdvllp ftqynrylal ynkykyfsga mdttsyreaa cchlakalnd 3241 fsnsgsdvly qppqisitsa vlqsgfrkma fpsgkvegcm vqvtcgtttl nglwlddvvy 3301 cprhvictse dmlnpnyedl lirksnhnfl vqagnvqlrv ighsmqncvl klkvdtanpk 3361 tpkykfvriq pgqtfsvlac yngspsgvyq camrhnftik gsflngscgs vgfnidydcv 3421 sfcymhhmel ptgvhagtdl egnfygpfvd rqtaqaagtd ttitvnvlaw lyaavingdr 3481 wflnrftttl ndfnlvamky nyepltqdhv dilgplsaqt giavldmcas lkellqngmn 3541 grtilgsall edeftpfdvv rqcsgvtfqs avkrtikgth hwllltilts llvlvqstqw 3601 slffflyena flpfamgiia msafammfvk hkhaflclfl lpslatvayf nmvympaswv 3661 mrimtwldmv dtslklkdcv myasavvlli lmtartvydd garrvwtlmn vltlvykvyy 3721 gnaldqaism waliisvtsn ysgvvttvmf largivfmcv eycpiffitg ntlqcimlvy 3781 cflgyfctcy fglfcllnry frltlgvydy lvstqefrym nsqgllppkn sidafklnik 3841 llgvggkpci kvatvqskms dvkctsvvll svlqqlrves ssklwaqcvq lhndillakd 3901 tteafekmvs llsvllsmqg avdinklcee mldnratlqa iasefsslps yaafataqea 3961 yeqavangds evvlkklkks lnvaksefdr daamqrklek madqamtqmy kqarsedkra 4021 kvtsamqtml ftmlrkldnd alnniinnar dgcvplniip lttaaklmvv ipdyntyknt 4081 cdgttftyas alweiqqvvd adskivqlse ismdnspnla wplivtalra nsavklqnne 4141 lspvalrqms caagttqtac tddnalayyn ttkggrfvla llsdlqdlkw arfpksdgtg 4201 tiyteleppc rfvtdtpkgp kvkylyfikg lnnlnrgmvl gslaatvrlq agnatevpan 4261 stvlsfcafa vdaakaykdy lasggqpitn cvkmlcthtg tgqaitvtpe anmdqesfgg 4321 ascclycrch idhpnpkgfc dlkgkyvqip ttcandpvgf tlkntvctvc gmwkgygcsc 4381 dqlrepmlqs adaqsflngf av //