LOCUS C_AAB30403 7090 aa linear VRL 11-MAY-2023
DEFINITION ORF1ab polyprotein [Severe acute respiratory syndrome coronavirus
2].
ACCESSION C_AAB30403
VERSION C_AAB30403.1
KEYWORDS .
SOURCE Severe acute respiratory syndrome coronavirus 2
ORGANISM Severe acute respiratory syndrome coronavirus 2
Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
Betacoronavirus; Sarbecovirus; Severe acute respiratory
syndrome-related coronavirus.
DBSOURCE accession C_AA014303.1
REFERENCE 1 (residues 1 to 7090)
AUTHORS Zhang,W.
TITLE Direct Submission
JOURNAL Submitted (11-MAY-2023) Microbe lab, Shanghai Municipal Center for
Disease Control & Prevention, west zhongshan road 1380, Shanghai
200336, China
COMMENT ##Genome-Assembly-Data-START##
Assembly Method :: Consensus sequence method v. 940-000133-00
Sequencing Technology :: MGISEQ-200
##Genome-Assembly-Data-END##
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..7090
/organism="Severe acute respiratory syndrome coronavirus 2"
/isolate="SARS-CoV-2/human/CHN/SH-XG2305-3675/2023"
/isolation_source="Nasopharyngeal swab"
/host="Homo sapiens; Host_age: 37; Host_sex: Female"
/country="China:Shanghai"
/collection_date="2023-05-01"
/note="Passage_details/history: Original"
Protein 1..7090
/product="ORF1ab polyprotein"
mat_peptide 1..177
/product="leader protein"
mat_peptide 178..815
/product="nsp2"
mat_peptide 816..2760
/product="nsp3"
mat_peptide 2761..3260
/product="nsp4"
mat_peptide 3261..3566
/product="3C-like proteinase"
mat_peptide 3567..3853
/product="nsp6"
mat_peptide 3854..3936
/product="nsp7"
mat_peptide 3937..4134
/product="nsp8"
mat_peptide 4135..4247
/product="nsp9"
mat_peptide 4248..4386
/product="nsp10"
mat_peptide 4387..5318
/product="RNA-dependent RNA polymerase"
mat_peptide 5319..5919
/product="helicase"
mat_peptide 5920..6446
/product="3'-to-5' exonuclease"
mat_peptide 6447..6792
/product="endoRNAse"
mat_peptide 6793..7090
/product="2'-O-ribose methyltransferase"
CDS 1..7090
/gene="ORF1ab"
/coded_by="join(C_AA014303.1:242..13426,
C_AA014303.1:13426..21513)"
/ribosomal_slippage
ORIGIN
1 meslvpgfne kthvqlslpv lqvrdvlvrg fgdsveevls earqhlrdgt cglvevekgv
61 lpqleqpyvf ikrsdartap hghvmvelva elegiqygrs getlgvlvph vgeipvayrk
121 vllrkngnkg agghrygadl dlgdelgtdp yedfqenwnt khssgvtrel mrelnggayt
181 ryvdnnfcgp dgyplecikd llaragkasc tlseqldfid tkrgvyccre heheiawyte
241 rseksyelqt pfeiklakkf dtfngecpnf vfplnsiikt iqprvekkkl dgfmgrirsv
301 ypvaspnecn qmclstlmkc dhcgetswqt gdfvkatcef cgtenltkeg attcgylpqn
361 avvkiycpac hnsevgpehs laeyhnesgl ktilrkggrt iafggcvfsy vgchnkcayw
421 vprasanigc nhigvvgegs eglndnllei lqkekvnini vgdfklneei aiilasfsas
481 tsafvetvkg ldykafkqiv escgnfkvtk gkakkgawni geqksilspl yafaseaarv
541 vrsifsrtle taqnsvrvlq kaaitildgi sqyslrlida mmftsdlatn nlvvmayitg
601 gvvqltsqwl tnifgtvyek lkpvldwlee kfkegveflr dgweivkfis tcaceivggq
661 ivtcakeike svqtffklvn kflalcadsi iiggaklkal nlgetfvths kglyrkcvks
721 reetgllmpl kapkeiifle getlptevlt eevvlktgdl qpleqptsea veaplvgtpv
781 cinglmllei kdtekycala pnmmvtnntf tlkggaptkv tfgddtviev qgyksvniif
841 elderidkvl nekcsaytve lgtevnefac vvadaviktl qpvselltpl gidldewsma
901 tyylfdesge fklashmycs fyppdedeee gdceeeefep stqyeygted dyqgkplefg
961 atsaalqpee eqeedwlddd sqqtvgqqdg sednqtttiq tivevqpqle meltpvvqti
1021 evnsfsgylk ltdnvyikna diveeakkvk ptvvvnaanv ylkhgggvag alnkatnnam
1081 qvesddyiat ngplkvggsc vlsghnlakh clhvvgpnvn kgediqllks ayenfnqhev
1141 llapllsagi fgadpihslr vcvdtvrtnv ylavfdknly dklvssflem ksekqveqki
1201 aeipkeevkp fiteskpsve qrkqddkkik acveevtttl eetkfltenl llyidingnl
1261 hpdsatlvsd iditflkkda pyivgdvvqe gvltavvipt kkasgtteml akalrkvptd
1321 nyittypgqg lngytveeak tvlkkcksaf yilpsiisne kqeilgtvsw nlremlahae
1381 etrklmpvcv etkaivstiq rkykgikiqe gvvdygarfy fytskttvas lintlndlne
1441 tlvtmplgyv thglnleeaa rymrslkvpa tvsvsspdav tayngyltss sktpeehfie
1501 tislagsykd wsysgqstql gieflkrgdk svyytsnptt fhldgevitf dnlktllslr
1561 evrtikvftt vdninlhtqv vdmsmtygqq fgptyldgad vtkikphnsh egktfyvlpn
1621 ddtlrveafe yyhttdpsfl grymsalnht kkwkypqvng ltsikwadnn cylatalltl
1681 qqielkfnpp alqdayyrar ageaanfcal ilaycnktvg elgdvretms ylfqhanlds
1741 ckrvlnvvck tcgqqqttlk gveavmymgt lsyeqfkkgv qipctcgkqa tkylvqqesp
1801 fvmmsappaq yelkhgtftc aseytgnyqc ghykhitske tlycidgall tksseykgpi
1861 tdvfykensy tttikpvtyk ldgvvcteid pkldnyykkd nsyfteqpid lvpnqpypna
1921 sfdnfkfvcd nikfaddlnq ltgykkpasr elkvtffpdl ngdvvaidyk hytpsfkkga
1981 kllhkpivwh vnnatnkaty kpntwcircl wstkpvetsn sfdvlkseda qgmdnlaced
2041 lkpvseevve nptiqkdvle cnvkttevvg diilkpanns lkiteevght dlmaayvdns
2101 sltikkpnel srvlglktla thglaavnsv pwdtianyak pflnkvvstt tnivtrclnr
2161 vctnympyff tlllqlctft rstnsrikas mpttiakntv ksvgkfclea sfnylkspnf
2221 skliniiiwf lllsvclgsl iystaalgvl msnlgmpsyc tgyregylns tnvtiatyct
2281 gsipcsvcls gldsldtyps letiqitiss fkwdltafgl vaewflayil ftrffyvlgl
2341 aaimqlffsy favhfisnsw lmwliinlvq mapisamvrm yiffasfyyv wksyvhvvdg
2401 cnsstcmmcy krnratrvec ttivngvrrs fyvyanggkg fcklhnwncv ncdtfcagst
2461 fisdevardl slqfkrpinp tdqssyivds vtvkngsihl yfdkagqkty erhslshfvn
2521 ldnlranntk gslpinvivf dgkskceess aksasvyysq lmcqpillld qalvsdvgds
2581 aevavkmfda yvntfsstfn vpmeklktlv ataeaelakn vsldnvlstf isaarqgfvd
2641 sdvetkdvve clklshqsdi evtgdscnny mltynkvenm tprdlgacid csarhinaqv
2701 akshnialiw nvkdfmslse qlrkqirsaa kknnlpfklt cattrqvvnv vttkialkgg
2761 kivnnwlkql ikvtlvflfv aaifylitpv hvmskhtdfs seiigykaid ggvtrdiast
2821 dtcfankhad fdtwfsqrgg sytndkacpl iaavitrevg fvvpglpgti lrttngdflh
2881 flprvfsavg nicytpskli eytdfatsac vlaaectifk dasgkpvpyc ydtnvlegsv
2941 ayeslrpdtr yvlmdgsiiq fpntylegsv rvvttfdsey crhgtcerse agvcvstsgr
3001 wvlnndyyrs lpgvfcgvda vnlftnmftp liqpigaldi sasivaggiv aivvtclayy
3061 fmrfrrafge yshvvafntl lflmsfivlc ltpvysflpg vysviylylt fyltndvsfl
3121 ahiqwmvmft plvpfwitia yiicistkhf ywffsnylkr rvvfngvsfs tfeeaalctf
3181 llnkemylkl rsdvllpftq ynrylalynk ykyfsgamdt tsyreaacch lakalndfsn
3241 sgsdvlyqpp qisitsavlq sgfrkmafps gkvegcmvqv tcgtttlngl wlddvvycpr
3301 hvictsedml npnyedllir ksnhnflvqa gnvqlrvigh smqncvlklk vdtanpktpk
3361 ykfvriqpgq tfsvlacyng spsgvyqcam rhnftikgsf lngscgsvgf nidydcvsfc
3421 ymhhmelptg vhagtdlegn fygpfvdrqt aqaagtdtti tvnvlawlya avingdrwfl
3481 nrftttlndf nlvamkynye pltqdhvdil gplsaqtgia vldmcaslke llqngmngrt
3541 ilgsallede ftpfdvvrqc sgvtfqsavk rtikgthqwl lltiltsllv lvqstqwslf
3601 fflyenaflp famgiiamsa fammfvkhkh aflclfllps latvayfnmv ympaswvmri
3661 mtwldmvdts lklkdcvmya savvllilmt artvyddgar rvwtlmnvlt lvykvyygna
3721 ldqaismwal iisvtsnysg vvttvmflar givfmcveyc piffitgntl qcimlvycfl
3781 gyfctcyfgl fcllnryfrl tlgvydylvs tqefrymnsq glfppknsid afklnikllg
3841 vggkpcikva tvqskmsdvk ctsvvllsvl qqlrvesssk lwaqcvqlhn dillakdtte
3901 afekmvslls vllsmqgavd inklceemld nratlqaias efsslpsyaa fataqeayeq
3961 avangdsevv lkklkkslnv aksefdrdaa mqrklekmad qamtqmykqa rsedkrakvt
4021 samqtmlftm lrkldndaln niinnardgc vplniipltt aaklmvvipd yntykntcdg
4081 ttftyasalw eiqqvvdads kivqlseism dnspnlawpl ivtalransa vklqnnelsp
4141 valrqmscaa gttqtactdd nalayynttk ggrfvlalls dlqdlkwarf pksdgtgtiy
4201 teleppcrfv tdtpkgpkvk ylyfikglnn lnrgmvlgsl aatvrlqagn atevpanstv
4261 lsfcafavda akaykdylas ggqpitncvk mlcthtgtgq aitvtpeanm dqesfggasc
4321 clycrchidh pnpkgfcdlk gkyvqipttc andpvgftlk ntvctvcgmw kgygcscdql
4381 repmlqsada qsflnrvcgv saarltpcgt gtstdvvyra fdiyndkvag fakflktncc
4441 rfqekdeddn lidsyfvvkr htfsnyqhee tiynllkdcp avakhdffkf ridgdmvphi
4501 srqrltkytm adlvyalrhf degncdtlke ilvtynccdd dyfnkkdwyd fvenpdilrv
4561 yanlgervrq allktvqfcd amrnagivgv ltldnqdlng nwydfgdfiq ttpgsgvpvv
4621 dsyysllmpi ltltraltae shvdtdltkp yikwdllkyd fteerlklfd ryfkywdqty
4681 hpncvncldd rcilhcanfn vlfstvfplt sfgplvrkif vdgvpfvvst gyhfrelgvv
4741 hnqdvnlhss rlsfkellvy aadpamhaas gnllldkrtt cfsvaaltnn vafqtvkpgn
4801 fnkdfydfav skgffkegss velkhfffaq dgnaaisdyd yyrynlptmc dirqllfvve
4861 vvdkyfdcyd ggcinanqvi vnnldksagf pfnkwgkarl yydsmsyedq dalfaytkrn
4921 viptitqmnl kyaisaknra rtvagvsics tmtnrqfhqk llksiaatrg atvvigtskf
4981 yggwhnmlkt vysdvenphl mgwdypkcdr ampnmlrima slvlarkhtt ccslshrfyr
5041 lanecaqvls emvmcgssly vkpggtssgd attayansvf nicqavtanv nallstdgnk
5101 iadkyvrnlq hrlyeclyrn rdvdtdfvne fyaylrkhfs mmilsddavv cfnstyasqg
5161 lvasiknfks vlyyqnnvfm seakcwtetd ltkgphefcs qhtmlvkqgd dyvylpypdp
5221 srilgagcfv ddivktdgtl mierfvslai daypltkhpn qeyadvfhly lqyirklhde
5281 ltghmldmys vmltndntsr ywepefyeam ytphtvlqav gacvlcnsqt slrcgacirr
5341 pflcckccyd hviptshklv lsvnpyvcna pgcdvtdvtq lylggmsyyc kshkppisfp
5401 lcangqvfgl ykntcvgsdn vtdfnaiatc dwtnagdyil antcterlkl faaetlkate
5461 etfklsygia tvrevlsdre lhlswevgkp rpplnrnyvf tgyrvtknsk vqigeytfek
5521 gdygdavvyr gtttyklnvg dyfvltshtv mplsaptlvp qehyvritgl yptlnisdef
5581 ssnvanyqkv gmqkystlqg ppgtgkshfa iglalyypsa rivytacsha avdalcekal
5641 kylpidkcsr iipararvec fdkfkvnstl eqyvfctvna lpettadivv fdeismatny
5701 dlsvvnarlc akhyvyigdp aqlpaprtll tkgtlepeyf nsvcrlmkti gpdmflgtcr
5761 rcpaeivdtv salvydnklk ahkdksaqcf kmfykgvith dvssainrpq igvvrefltr
5821 npawrkavfi spynsqnava skilglptqt vdssqgseyd yviftqttet ahscnvnrfn
5881 vaitrakvgi lcimsdrdly dklqftslei prrnvatlqa envtglfkdc skvitglhpt
5941 qapthlsvdt kfkteglcvd vpgipkdmty rrlismmgfk mnyqvngypn mfitreeair
6001 hvrawigfdv egchatreav gtnlplqlgf stgvnlvavp tgyvdtpnnt dfsrvsakpp
6061 pgdqfkhlip lmykglpwnv vrikivqmls dtlknlsdrv vfvlwahgfe ltsmkyfvki
6121 gpertcclcd rratcfstas ytyacwhhsi gfdyvynpfm idvqqwgftg nlqsnhdlyc
6181 qvhgnahvas cdaimtrcla vhecfvkrvd wtieypiigd elkinaacrk vqhmvvkaal
6241 ladkfpvlhd ignpkaikcv pqadvewkfy daqpcsdkay kieelfysya thsdkftdgv
6301 clfwncnvdr ypansivcrf dtrvlsnlnl pgcdggslyv nkhafhtpaf dksafvnlkq
6361 lpffyysdsp ceshgkqvvs didyvplksa tcitrcnlgg avcrhhaney rlyldaynmm
6421 isagfslwvy kqfdtynlwn tftrlqslen vafnvvnkgh fdgqqgevpv siinntvytk
6481 vdgvdvelfe nkttlpvnva felwakrnik pvpevkilnn lgvdiaantv iwdykrdapa
6541 histigvcsm tdiakkpiet icapltvffd grvdgqvdlf rnarngvlit egsvkglqps
6601 vgpkqaslng vtligeavkt qfnyykkvdg vvqqlpetyf tqsrnlqefk prsqmeidfl
6661 elamdefier yklegyafeh ivygdfshsq lgglhlligl akrfkespfe ledfipmdst
6721 vknyfitdaq tgsskcvcsv idlllddfve iiksqdlsvv skvvkvtidy teisfmlwck
6781 dghvetfypk lqssqawqpg vampnlykmq rmllekcdlq nygdsatlpk gimmnvakyt
6841 qlcqylntlt lavpynmrvi hfgagsdkgv apgtavlrqw lptgtllvds dlndfvsdad
6901 stligdcatv htankwdlii sdmydpktkn vtkendskeg fftyicgfiq qklalggsva
6961 ikitehswna dlyklmghfa wwtafvtnvn assseaflig cnylgkpreq idgyvmhany
7021 ifwrntnpiq lssyslfdms kfplklrgta vmslkegqin dmilsllskg rliirennrv
7081 vissdvlvnn
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