LOCUS C_AAB30470 7093 aa linear VRL 11-MAY-2023
DEFINITION ORF1ab polyprotein [Severe acute respiratory syndrome coronavirus
2].
ACCESSION C_AAB30470
VERSION C_AAB30470.1
KEYWORDS .
SOURCE Severe acute respiratory syndrome coronavirus 2
ORGANISM Severe acute respiratory syndrome coronavirus 2
Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
Betacoronavirus; Sarbecovirus; Severe acute respiratory
syndrome-related coronavirus.
DBSOURCE accession C_AA014309.1
REFERENCE 1 (residues 1 to 7093)
AUTHORS Zhang,W.
TITLE Direct Submission
JOURNAL Submitted (11-MAY-2023) Microbe lab, Shanghai Municipal Center for
Disease Control & Prevention, west zhongshan road 1380, Shanghai
200336, China
COMMENT ##Genome-Assembly-Data-START##
Assembly Method :: Consensus sequence method v. 940-000133-00
Sequencing Technology :: MGISEQ-200
##Genome-Assembly-Data-END##
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..7093
/organism="Severe acute respiratory syndrome coronavirus 2"
/isolate="SARS-CoV-2/human/CHN/SH-XG2305-3694/2023"
/isolation_source="Pharyngeal swab"
/host="Homo sapiens; Host_age: 26; Host_sex: Female"
/country="China:Shanghai"
/collection_date="2023-05-02"
/note="Passage_details/history: Original"
Protein 1..7093
/product="ORF1ab polyprotein"
mat_peptide 1..180
/product="leader protein"
mat_peptide 181..818
/product="nsp2"
mat_peptide 819..2763
/product="nsp3"
mat_peptide 2764..3263
/product="nsp4"
mat_peptide 3264..3569
/product="3C-like proteinase"
mat_peptide 3570..3856
/product="nsp6"
mat_peptide 3857..3939
/product="nsp7"
mat_peptide 3940..4137
/product="nsp8"
mat_peptide 4138..4250
/product="nsp9"
mat_peptide 4251..4389
/product="nsp10"
mat_peptide 4390..5321
/product="RNA-dependent RNA polymerase"
mat_peptide 5322..5922
/product="helicase"
mat_peptide 5923..6449
/product="3'-to-5' exonuclease"
mat_peptide 6450..6795
/product="endoRNAse"
mat_peptide 6796..7093
/product="2'-O-ribose methyltransferase"
CDS 1..7093
/gene="ORF1ab"
/coded_by="join(C_AA014309.1:242..13435,
C_AA014309.1:13435..21522)"
/ribosomal_slippage
ORIGIN
1 meslvpgfne kthvqlslpv lqvrdvlvrg fgdsveevls earqhlrdgt cglvevekgv
61 lpqleqpyvf ikrsdartap hghvmvelva elegiqygrs getlgvlvph vgeipvayrk
121 vllrkngnkg agghrygadl ksfdlgdelg tdpyedfqen wntkhssgvt relmrelngg
181 aytryvdnnf cgpdgyplec ikdllaragk asctlseqld fidtkrgvyc creheheiaw
241 yterseksye lqtpfeikla kkfdtfngec pnfvfplnsi iktiqprvek kkldgfmgri
301 rsvypvaspn ecnqmclstl mkcdhcgets wqtgdfvkat cefcgtenlt kegattcgyl
361 pqnavvkiyc pachnsevgp ehslaeyhne sglktilrkg grtiafggcv fsyvgchnkc
421 aywvprasan igcnhtgvvg egseglndnl leilqkekvn inivgdfkln eeiaiilasf
481 sastsafvet vkgldykafk qivescgnfk vtkgkakkga wnigeqksil splyafasea
541 arvvrsifsr tletaqnsvr vlqkaaitil dgisqyslrl idammftsdl atnnlvvmay
601 itggvvqlts qwltnifgtv yeklkpvldw leekfkegve flrdgweivk fistcaceiv
661 ggqivtcake ikesvqtffk lvnkflalca dsiiiggakl kalnlgetfv thskglyrkc
721 vksreetgll mplkapkeii flegetlptk vlteevvlkt gdlqpleqpt seaveaplvg
781 tpvcinglml leikdtekyc alapnmmvtn ntftlkggap tkvtfgddtv ievqgyksvn
841 iifelderid kvlnekcsay tvelgtevne facvvadavi ktlqpvsell tplgidldew
901 smatyylfde sgefklashm ycsfyppded eeegdceeee fepstqyeyg teddyqgkpl
961 efgatsaalq peeeqeedwl dddsqqtvgq qdgsednqtt tiqtivevqp qlemeltpvv
1021 qtievnsfsg ylkltdnvyi knadiveeak kvkptvvvna anvylkhggg vagalnkatn
1081 namqvesddy iatngplkvg gscvlsghnl akhclhvvgp nvnkgediql lksayenfnq
1141 hevllaplls agifgadpih slrvcvdtvr tnvylavfdk nlydklvssf lemksekqve
1201 qkiaeipkee vkpfiteskp sveqrkqddk kikacveevt ttleetkflt enlllyidin
1261 gnlhpdsatl vsdiditflk kyapyivgdv vqegvltavv iptkkasgtt emlakalrkv
1321 ptdnyittyp gqglngytve eaktvlkkck safyilpsii snekqeilgt vswnlremla
1381 haeetrklmp vcvetkaivs tiqrkykgik iqegvvdyga rfyfytsktt vaslintlnd
1441 lnetlvtmpl gyvthglnle eaarymrslk vpatvsvssp davtayngyl tsssktpeeh
1501 fietislags ykdwsysgqs tqlgieflkr gdksvyytsn pttfhldgev itfdnlktll
1561 slrevrtikv fttvdninlh tqvvdmsmty gqqfgptyld gadvtkikph nshegktfyv
1621 lpnddtlrve afeyyhttdp sflgrymsal nhtkkwkypq vngltsikwa dnncylatal
1681 ltlqqielkf nppalqdayy rarageaanf calilaycnk tvgelgdvre tmsylfqhan
1741 ldsckrvlnv vcktcgqqqi tlkgveavmy mgtlsyeqfk kgvqipctcg kqatkylvqq
1801 espfvmmsap paqyelkhgt ftcaseytgn yqcghykhit sketlycidg alltksseyk
1861 gpitdvfyke nsytttikpv tykldgvvct eidpkldnyy kkdnsyfteq pidlvpnqpy
1921 pnasfdnfkf vcdnikfadd lnqltgykkp asrelkvtff pdlngdvvai dykhytpsfk
1981 kgakllhkpi vwhvnnatnk atykpntwci rclwstkpve tsnsfdvlks edaqgmdnla
2041 cedlkpvsee vvenptiqkd vlecnvktte vvgdiilkpa nnslkiteev ghtdlmaayv
2101 dnssltikkp nelsrvlglk tlathglaav nsvpwdtian yakpflnkvv stttnivtrc
2161 lnrvctnymp yfftlllqlc tftrstnsri kasmpttiak ntvksvgkfc leasfnylks
2221 pnfsklinii iwflllsvcl gsliystaal gvlmsnlgmp syctgyregy lnstnvtiat
2281 yctgsipcsv clsgldsldt ypsletiqit issfkwdlta fglvaewfla yilftrffyv
2341 lglaaimqlf fsyfavhfis nswlmwliin lvqmapisam vrmyiffasf yyvwksyvhv
2401 vdgcnsstcm mcykrnratr vecttivngv rrsfyvyang gkgfcklhnw ncvncdtfca
2461 gstfisdeva rdlslqfkrp inptdqssyi vdsvtvkngs ihlyfdkagq ktyerhslsh
2521 fvnldnlran ntkgslpinv ivfdgkskce essaksasvy ysqlmcqpil lldqalvsdv
2581 gdsaevavkm fdayvntfss tfnvpmeklk tlvataeael aknvsldnvl stfisaarqg
2641 fvdsdvetkd vveclklshq sdievtgdsc nnymltynkv enmtprdlga cidcsarhin
2701 aqvakshnia liwnvkdfms lseqlrkqir saakknnlpf kltcattrqv vnvvttkial
2761 kggkivnnwl kqlikvtlvf lfvaaifyli tpvhvmskht dfsseiigyk aidggvtrdi
2821 astdtcfank hadfdtwfsq rggsytndka cpliaavitr evgfvvpglp gtilrttngd
2881 flhflprvfs avgnicytps klieytdfat sacvlaaect ifkdasgkpv pycydtnvle
2941 gsvayeslrp dtryvlmdgs iiqfpntyle gsvrvvttfd seycrhgtce rseagvcvst
3001 sgrwvlnndy yrslpgvfcg vdavnlftnm ftpliqpiga ldisasivag givaivvtcl
3061 ayyfmrfrra fgeyshvvaf ntllflmsfi vlcltpvysf lpgvysviyl yltfyltndv
3121 sflahiqwmv mftplvpfwi tiayiicist khfywffsny lkrrvvfngv sfstfeeaal
3181 ctfllnkemy lklrsdvllp ftqynrylal ynkykyfsga mdttsyreaa cchlakalnd
3241 fsnsgsdvly qppqisitsa vlqsgfrkma fpsgkvegcm vqvtcgtttl nglwlddvvy
3301 cprhvictse dmlnpnyedl lirksnhnfl vqagnvqlrv ighsmqncvl klkvdtanpk
3361 tpkykfvriq pgqtfsvlac yngspsgvyq camrhnftik gsflngscgs vgfnidydcv
3421 sfcymhhmel ptgvhagtdl egnfygpfvd rqtaqaagtd ttitvnvlaw lyaavingdr
3481 wflnrftttl ndfnlvamky nyepltqdhv dilgplsaqt giavldmcas lkellqngmn
3541 grtilgsall edeftpfdvv rqcsgvtfqs avkrtikgth hwllltilts llvlvqstqw
3601 slffflyena flpfamgiia msafammfvk hkhaflclfl lpslatvayf nmvympaswv
3661 mrimtwldmv dtslklkdcv myasavvlli lmtartvydd garrvwtlmn vltlvykvyy
3721 gnaldqaism waliisvtsn ysgvvttvmf largivfmcv eycpiffitg ntlqcimlvy
3781 cflgyfctcy fglfcllnry frltlgvydy lvstqefrym nsqgllppkn sidafklnik
3841 llgvggkpci kvatvqskms dvkctsvvll svlqqlrves ssklwaqcvq lhndillakd
3901 tteafekmvs llsvllsmqg avdinklcee mldnratlqa iasefsslps yaafataqea
3961 yeqavangds evvlkklkks lnvaksefdr daamqrklek madqamtqmy kqarsedkra
4021 kvtsamqtml ftmlrkldnd alnniinnar dgcvplniip lttaaklmvv ipdyntyknt
4081 cdgttftyas alweiqqvvd adskivqlse ismdnspnla wplivtalra nsavklqnne
4141 lspvalrqms caagttqtac tddnalayyn ttkggrfvla llsdlqdlkw arfpksdgtg
4201 tiyteleppc rfvtdtpkgp kvkylyfikg lnnlnrgmvl gslaatvrlq agnatevpan
4261 stvlsfcafa vdaakaykdy lasggqpitn cvkmlcthtg tgqaitvtpe anmdqesfgg
4321 ascclycrch idhpnpkgfc dlkgkyvqip ttcandpvgf tlkntvctvc gmwkgygcsc
4381 dqlrepmlqs adaqsflnrv cgvsaarltp cgtgtstdvv yrafdiyndk vagfakflkt
4441 nccrfqekde ddnlidsyfv vkrhtfsnyq heetiynllk dcpavakhdf fkfridgdmv
4501 phisrqrltk ytmadlvyal rhfdegncdt lkeilvtync cdddyfnkkd wydfvenpdi
4561 lrvyanlger vrqallktvq fcdamrnagi vgvltldnqd lngnwydfgd fiqttpgsgv
4621 pvvdsyysll mpiltltral taeshvdtdl tkpyikwdll kydfteerlk lfdryfkywd
4681 qtyhpncvnc lddrcilhca nfnvlfstvf pltsfgplvr kifvdgvpfv vstgyhfrel
4741 gvvhnqdvnl hssrlsfkel lvyaadpamh aasgnllldk rttcfsvaal tnnvafqtvk
4801 pgnfnkdfyd favskgffke gssvelkhff faqdgnaais dydyyrynlp tmcdirqllf
4861 vvevvdkyfd cydggcinan qvivnnldks agfpfnkwgk arlyydsmsy edqdalfayt
4921 krnviptitq mnlkyaisak nrartvagvs icstmtnrqf hqkllksiaa trgatvvigt
4981 skfyggwhnm lktvysdven phlmgwdypk cdrampnmlr imaslvlark httccslshr
5041 fyrlanecaq vlsemvmcgs slyvkpggts sgdattayan svfnicqavt anvnallstd
5101 gnkiadkyvr nlqhrlyecl yrnrdvdtdf vnefyaylrk hfsmmilsdd avvcfnstya
5161 sqglvasikn fksvlyyqnn vfmseakcwt etdltkgphe fcsqhtmlvk qgddyvylpy
5221 pdpsrilgag cfvddivktd gtlmierfvs laidaypltk hpnqeyadvf hlylqyirkl
5281 hdeltghmld mysvmltndn tsrywepefy eamytphtvl qavgacvlcn sqtslrcgac
5341 irrpflcckc cydhviptsh klvlsvnpyv cnapgcdvtd vtqlylggms yyckshkppi
5401 sfplcangqv fglykntcvg sdnvtdfnai atcdwtnagd yilantcter lklfaaetlk
5461 ateetfklsy giatvrevls drelhlswev gkprpplnrn yvftgyrvtk nskvqigeyt
5521 fekgdygdav vyrgtttykl nvgdyfvlts htvmplsapt lvpqehyvri tglyptlnis
5581 defssnvany qkvgmqkyst lqgppgtgks hfaiglalyy psarivytac shaavdalce
5641 kalkylpidk csriiparar vecfdkfkvn stleqyvfct vnalpettad ivvfdeisma
5701 tnydlsvvna rlcakhyvyi gdpaqlpapr tlltkgtlep eyfnsvcrlm ktigpdmflg
5761 tcrrcpaeiv dtvsalvydn klkahkdksa qcfkmfykgv ithdvssain rpqigvvref
5821 ltrnpawrka vfispynsqn avaskilglp tqtvdssqgs eydyviftqt tetahscnvn
5881 rfnvaitrak vgilcimsdr dlydklqfts leiprrnvat lqaenvtglf kdcskvitgl
5941 hptqapthls vdtkfktegl cvdvpgipkd mtyrrlismm gfkmnyqvng ypnmfitree
6001 airhvrawig fdvegchatr eavgtnlplq lgfstgvnlv avptgyvdtp nntdfsrvsa
6061 kpppgdqfkh liplmykglp wnvvrikivq mlsdtlknls drvvfvlwah gfeltsmkyf
6121 vkigpertcc lcdrratcfs tasdtyacwh hsigfdyvyn pfmidvqqwg ftgnlqsnhd
6181 lycqvhgnah vascdaimtr clavhecfvk rvdwtieypi igdelkinaa crkvqhmvvk
6241 aalladkfpv lhdignpkai kcvpqadvew kfydaqpcsd kaykieelfy syathsdkft
6301 dgvclfwncn vdrypansiv crfdtrvlsn lnlpgcdggs lyvnkhafht pafdksafvn
6361 lkqlpffyys dspceshgkq vvsdidyvpl ksatcitrcn lggavcrhha neyrlylday
6421 nmmisagfsl wvykqfdtyn lwntftrlqs lenvafnvvn kghfdgqqge vpvsiinntv
6481 ytkvdgvdve lfenkttlpv nvafelwakr nikpvpevki lnnlgvdiaa ntviwdykrd
6541 apahistigv csmtdiakkp ieticapltv ffdgrvdgqv dlfrnarngv litegsvkgl
6601 qpsvgpkqas lngvtligea vktqfnyykk vdgvvqqlpe tyftqsrnlq efkprsqmei
6661 dflelamdef ieryklegya fehivygdfs hsqlgglhll iglakrfkes pfeledfipm
6721 dstvknyfit daqtgsskcv csvidllldd fveiiksqdl svvskvvkvt idyteisfml
6781 wckdghvetf ypklqssqaw qpgvampnly kmqrmllekc dlqnygdsat lpkgimmnva
6841 kytqlcqyln tltlavpynm rvihfgagsd kgvapgtavl rqwlptgtll vdsdlndfvs
6901 dadstligdc atvhtankwd liisdmydpk tknvtkends kegfftyicg fiqqklalgg
6961 svaikitehs wnadlyklmg hfawwtafvt nvnassseaf ligcnylgkp reqidgyvmh
7021 anyifwrntn piqlssyslf dmskfplklr gtavmslkeg qindmilsll skgrliiren
7081 nrvvissdvl vnn
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