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ORF1a polyprotein [Severe acute respiratory syndrome coronavirus 2].

GenBase:
C_AAH32187.1

LOCUS       C_AAH32187              4402 aa            linear   VRL 07-MAY-2024
DEFINITION  ORF1a polyprotein [Severe acute respiratory syndrome coronavirus 2].
ACCESSION   C_AAH32187
VERSION     C_AAH32187.1
KEYWORDS    .
SOURCE      Severe acute respiratory syndrome coronavirus 2
  ORGANISM  Severe acute respiratory syndrome coronavirus 2
            Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
            Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
            Betacoronavirus; Sarbecovirus; Severe acute respiratory
            syndrome-related coronavirus.
DBSOURCE    accession C_AA070733.1
REFERENCE   1  (residues 1 to 4402)
  AUTHORS   Hong,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAY-2024) inspection and verification office, Center
            for Disease Control and Prevention of Tibet Autonomous Region,
            Linkuo northroad 21, Lhasa, Tibet 850000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method       :: weiweilai v. 20240507
            Sequencing Technology :: Illumina
            ##Genome-Assembly-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..4402
                     /organism="Severe acute respiratory syndrome coronavirus 2"
                     /isolate="SARS-CoV-2/human/CHN/XZCDC_0011/2024"
                     /host="Homo sapiens; Host_age: 21 years; Host_age_unit:
                     year"
                     /country="China:Xizang"
                     /collection_date="2024-03-20"
     Protein         1..4402
                     /product="ORF1a polyprotein"
     mat_peptide     1..180
                     /product="leader protein"
     mat_peptide     181..818
                     /product="nsp2"
     mat_peptide     819..2763
                     /product="nsp3"
     mat_peptide     2764..3263
                     /product="nsp4"
     mat_peptide     3264..3569
                     /product="3C-like proteinase"
     mat_peptide     3570..3856
                     /product="nsp6"
     mat_peptide     3857..3939
                     /product="nsp7"
     mat_peptide     3940..4137
                     /product="nsp8"
     mat_peptide     4138..4250
                     /product="nsp9"
     mat_peptide     4251..4389
                     /product="nsp10"
     mat_peptide     4390..4402
                     /product="nsp11"
     CDS             1..4402
                     /gene="ORF1ab"
                     /coded_by="C_AA070733.1:253..13461"
ORIGIN
        1 meslvpgfne kthvqlslpv lqvrdvlvrg fgdsveevls earqhlkdgt cglvevekgv
       61 lpqleqpyvf ikrsdartap hghvmvelva elegiqygrs getlgvlvph vgeipvayrk
      121 vllrkngnkg agghrygadl ksfdlgdelg tdpyedfqen wntkhssgvt relmrelngg
      181 aytryvdnnf cgpdgyplec ikdllaragk dsctlseqld fidtkrgvyc creheheiaw
      241 yterseksye lqtpfeikla kkfdtfngec pnfvfplnsi iktiqprvek kkldgfmgri
      301 rsvypvaspn ecnqmclstl mkcdhcgets wqtgdfvkat cefcgtenlt kegattcgyl
      361 pqnavvkiyc pachnsevgp ehslaeyhne sglktilrkg grtiafggcv fsyvgchnkc
      421 aywvprasan igcnhtgvvg egseglndnl leilqkekvn inivgdfkln eeiaiilasf
      481 sastsafvet vkgldykafk qivescgnfk vtkgkakkga wnigeqksil splyafasea
      541 arvvrsifsr tletaqnsvr vlqkaaitil dgisqyslrl idammftsdl atnnlvvmay
      601 itggvvqlts qwltnifgtv yeklkpvldw leekfkegve flrdgweivk fistcaceiv
      661 ggqivtcake ikesvqtffk lvnkflalca dsiiiggakl kalnlgetfv thskglyrkc
      721 vksreetgll mplkapkeii flegetlpte vlteevvlkt gdlqpleqpt seaveaplvg
      781 tpvcinglml leikdtekyc alapnmmvtn ntftlkggap tkvtfgddtv ievqgyksvn
      841 iifelderid kvlnekcsay tvelgtevne facvvadavi ktlqpvsell tplgidldew
      901 smatyylfde sgefklashm ycsfyppded eeegdceeee fepstqyeyg teddyqgkpl
      961 efgatsaalq peeeqeedwl dddsqqtvgq qdgsednqtt tiqtivevqp qlemeltpvv
     1021 qtievnsfsg ylkltdnvyi knadiveeak kvkptlvvna anvylkhggg vagalnkatn
     1081 namqvesddy iatngplkvg gscvlsghnl akhclhvvgp nvnkgediql lksayenfnq
     1141 hevllaplls agifgadpih slrvcvdtvr tnvylavfdk nlydklvssf lemksekqve
     1201 qkiaeipkee vkpfiteskp sveqrkqddk kikacveevt ttleetkflt enlllyidin
     1261 gnlhpdsatl vsdiditflk kdapyivgdv vqegvltavv iptkkasgtt emlakalrkv
     1321 ptdnyittyp gqglngytve eaktvlkkck safyilpsii snekqeilgt vswnlremla
     1381 haeetrklmp vcvetkaivs tiqrkykgik iqegvvdyga rfyfytsktt vaslintlnd
     1441 lnetlvtmpl gyvthglnle eaarymrslk vpatvsvssp davtayngyl tsssktpeeh
     1501 fietislags ykdwsysgqs tqlgieflkr gdksvyytsn pttfhldgev itfdnlktll
     1561 slrevrtikv fttvdninlh tqvvdmsmty gqqfgptyld gadvtkikph nshegktfyv
     1621 lpnddtlrve afeyyhttdp sflgrymsal nhtkkwkypq vngltsikwa dnncylatal
     1681 ltlqqielkf nppalqdayy rarageaanf calilaycnk tvgelgdvre tmsylfqhan
     1741 ldsckrvlnv vcktcgqqqt tlkgveavmy mgtlsyeqfk kgvqipctcg kqatkylvqq
     1801 espfvmmsap paqyelkhgt ftcaseytgn yqcghykhit sketlycidg alltksseyk
     1861 gpitdvfyke nsytttikpv tykldgvvct eidpkldnyy kkdnsyfteq pidlvpnqpy
     1921 pnasfdnfkf vcdnikfadd lnqltgykkp asrelkvtff pdlngdvvai dyrhytpsfk
     1981 kgakllhkpi vwhvnnatnk atykpntwci rclwstkpve tsnsfdvlks edaqgmdnla
     2041 cedlkpvsee vvenptiqkd vlecnvktte vvgdiilkpa nnslkiteev ghtdlmaayv
     2101 dnssltikkp nelsrvlglk tlathglaav nsvpwdtian yakpflnkvv stttnivtrc
     2161 lnrvctnymp yfftlllqlc tftrstnsri kasmpttiak ntvksvgkfc leasfnylks
     2221 pnfsklinii iwflllsvcl gsliystaal gvlmsnlgmp syctgyregy lnstnvtiat
     2281 yctgsipcsv clsgldsldt ypsletiqit issfkwdlta fglvaewfla yilftrffyv
     2341 lglaaimqlf fsyfavhfis nswlmwliin lvqmapisam vrmyiffasf yyvwksyvhv
     2401 vdgcnsstcm mcykrnratr vecttivngv rrsfyvyang gkgfcklhnw ncvncdtfca
     2461 gstfisdeva rdlslqfkrp inptdqssyi vdsvtvkngs ihlyfdkagq ktyerhslsh
     2521 fvnldslran ntkgslpinv ivfdgkskce essaksasvy ysqlmcqpil lldqalvsdv
     2581 gdsaevavkm fdayvntfss tfnvpmeklk tlvataeael aknvsldnvl stfisaarqg
     2641 fvdsdvetkd vveclklshq sdievtgdsc nnymltynkv enmtprdlga cidcsarhin
     2701 aqvakshnit liwnvkdfms lseqlrkqir saakknnlpf kltcattrqv vnvvttkial
     2761 kggkivnnwl kqlikvtlvf lfvaaifyli tpvhvmskht dfsseiigyk aidggvtrdi
     2821 astdtcfank hadfdtwfsq rggsytndka cpliaavitr evgfvvpglp gtilrttngd
     2881 flhflprvfs avgnicytps klieytdfat sacvlaaect ifkdasgkpv pycydtnvle
     2941 gsvayeslrp dtryvlmdgs iiqfpntyle gsvrvvttfd seycrhgtce rseagvcvst
     3001 sgrwvlnndy yrslpgvfcg vdavnlftnm ftpliqpiga ldisasivag givaivvtcl
     3061 ayyfmrfrra fgeyshvvaf ntllflmsfi vlcltpvysf lpgvysviyl yltfyltndv
     3121 sflahiqwmv mftplvpfwi tiayiicist khfywffsny lkrrvvfngv sfstfeeaal
     3181 ctfllnkemy lklrsdvllp ltqynrylal ynkykyfsga mdttsyreaa cchlakalnd
     3241 fsnsgsdvly qppqisitsa vlqsgfrkma fpsgkvegcm vqvtcgtttl nglwlddvvy
     3301 cprhvictse dmlnpnyedl lirksnhnfl vqagnvqlrv ighsmqncvl klkvdtanpk
     3361 tpkykfvriq pgqtfsvlac yngspsgvyq camrhnftik gsflngscgs vgfnidydcv
     3421 sfcymhhmel ptgvhagtdl egnfygpfvd rqtaqaagtd ttitvnvlaw lyaavingdr
     3481 wflnrftttl ndfnlvamky nyepltqdhv dilgplsaqt giavldmcas lkellqngmn
     3541 grtilgsall edeftpfdvv rqcsgvtfqs avkrtikgth hwllltilts llflvqstqw
     3601 slffflyena flpfamgiia msafammfvk hkhaflclfl lpslatvayf nmvympaswv
     3661 mrimtwldmv dtslklkdcv myasavvlli lmtartvydd garrvwtlmn vltlvykvyy
     3721 gnaldqaism waliisvtsn ysgvvttvmf largivfmcv eycpiffitg ntlqcimlvy
     3781 cflgyfctcy fglfcllnry frltlgvydy lvstqefkym nsqgllppkn sidafklnik
     3841 llgvggkpci kvatvqskms dvkctsvvll svlqqlrves ssklwaqcvq lhndillakd
     3901 tteafekmvs llsvllsmqg avdinklcee mldnratlqa iasefsslps yaafataqea
     3961 yeqavangds evvlkklkks lnvaksefdr daamqrklek madqamtqmy kqarsedkra
     4021 kvtsamqtml ftmlrkldnd alnniinnar dgcvplniip lttaaklmvv ipdyntyknt
     4081 cdgttftyas alweiqqvvd adskivqlse ismdnspnla wplivtalra nsavklqnne
     4141 lspvalrqms caagttqtac tddnalayyn tikggrfvla llsdlqdlkw arfpksdgtg
     4201 tiyteleppc rfvtdtpkgp kvkylyfikg lnnlnrgmvl gslaatvrlq agnatevpan
     4261 stvlsfcafa vdaakaykdy lasggqpitn cvkmlcthtg tgqaitvtpe anmdqesfgg
     4321 ascclycrch idhpnpkgfc dlkgkyvqip ttcandpvgf tlkntvctvc gmwkgygcsc
     4381 dqlrepmlqs adaqsflngf av
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