The detail information of Paroxysmal dyskinesia
Basic Information

Another Name: Episodic Dyskinesia

Disease Description: Another form of dyskinesia in dogs is paroxysmal or episodic dyskinesia.You may hear of it as atypical seizures, Chinook seizures and Bichon dyskinesia.

Inherit Mode: -

Disease Symptom: Symptoms are similar to seizures and include hyperflexion of limbs, loss of coordination and stability, uncontrollable trembling and the inability to walk. Unlike with seizures, however, an affected dog maintains consciousness and is able to follow basic commands during an episode.

Disease Cause: Not much is known about the condition or its causes.

Disease Diagnose: -

Treat Method: -

Breeder Advice: If your dog suffers these episodes, consult your veterinarian to first rule out traditional seizures.

Disease Description Source: Link

Associated Diseases
Disease Name Other Name Mode of inheritance Link ID Possible OMIM ID Gene
Dyskinesia, paroxysmal - Multifactorial - -
Dyskinesia, paroxysmal, PIGN-related - Autosomal Recessive PIGN
Associated Breeds
There are associated breeds.
References
2021 Mandigers,P.J.J.,VanSteenbeek,F.G.,Bergmann,W.,Vos-Loohuis,M.,Leegwater,P.A.: :
A knockout mutation associated with juvenile paroxysmal dyskinesia in Markiesje dogs indicates SOD1 pleiotropy. Hum Genet :, 2021.
Pubmed reference: 33677640 . DOI: 10.1007/s00439-021-02271-6 .
2017 Stassen,Q.E.M.,Koskinen,L.L.E.,vanSteenbeek,F.G.,Seppälä,E.H.,Jokinen,T.S.,Prins,P.G.M.,Bok,H.G.J.,Zandvliet,M.M.J.M.,Vos-Loohuis,M.,Leegwater,P.A.J.,Lohi,H.: :
Paroxysmal Dyskinesia in Border Terriers: Clinical, Epidemiological, and Genetic Investigations. J Vet Intern Med 31:1123-1131, 2017.
Pubmed reference: 28703446 . DOI: 10.1111/jvim.14731 .
2017 Stassen,Q.E.M.,Koskinen,L.L.E.,vanSteenbeek,F.G.,Seppälä,E.H.,Jokinen,T.S.,Prins,P.G.M.,Bok,H.G.J.,Zandvliet,M.M.J.M.,Vos-Loohuis,M.,Leegwater,P.A.J.,Lohi,H.: :
Paroxysmal Dyskinesia in Border Terriers: Clinical, Epidemiological, and Genetic Investigations. J Vet Intern Med 31:1123-1131, 2017.
Pubmed reference: 28703446 . DOI: 10.1111/jvim.14731 .
2016 Lowrie,M.,Garosi,L.: :
Natural history of canine paroxysmal movement disorders in Labrador retrievers and Jack Russell terriers. Vet J 213:33-7, 2016.
Pubmed reference: 27240912 . DOI: 10.1016/j.tvjl.2016.03.007 .
2016 Kolicheski,A.L.,Johnson,G.S.,Mhlanga-Mutangadura,T.,Taylor,J.F.,Schnabel,R.D.,Kinoshita,T.,Murakami,Y.,O'Brien,D.P.: :
A homozygous PIGN missense mutation in Soft-Coated Wheaten Terriers with a canine paroxysmal dyskinesia. Neurogenetics :, 2016.
Pubmed reference: 27891564 . DOI: 10.1007/s10048-016-0502-4 .
2014 Black,V.,Garosi,L.,Lowrie,M.,Harvey,R.J.,Gale,J.: :
Phenotypic characterisation of canine epileptoid cramping syndrome in the Border terrier. J Small Anim Pract 55:102-7, 2014.
Pubmed reference: 24372194 . DOI: 10.1111/jsap.12170 .
2014 Guevar,J.,DeDecker,S.,VanHam,L.M.,Fischer,A.,Volk,H.A.: :
Idiopathic head tremor in English bulldogs. Mov Disord 29:191-4, 2014.
Pubmed reference: 24375621 . DOI: 10.1002/mds.25767 .
2011 Wolf,M.,Bruehschwein,A.,Sauter-Louis,C.,Sewell,A.C.,Fischer,A.: :
An inherited episodic head tremor syndrome in Doberman pinscher dogs. Mov Disord 26:2381-6, 2011.
Pubmed reference: 21915908 . DOI: 10.1002/mds.23936 .
2010 Packer,R.A.,Patterson,E.E.,Taylor,J.F.,Coates,J.R.,Schnabel,R.D.,O'Brien,D.P.: :
Characterization and mode of inheritance of a paroxysmal dyskinesia in Chinook dogs. J Vet Intern Med 24:1305-13, 2010.
Pubmed reference: 21054538 . DOI: 10.1111/j.1939-1676.2010.0629.x .
2004 Shelton,G.D.: :
Muscle pain, cramps and hypertonicity. Vet Clin North Am Small Anim Pract 34:1483-96, 2004.
Pubmed reference: 15474685 . DOI: 10.1016/j.cvsm.2004.05.019 .
2001 Penderis,J.,Franklin,R.J.: :
Dyskinesia in an adult bichon frise. J Small Anim Pract 42:24-5, 2001.
Pubmed reference: 11219819 .
1983 Herrtage,ME.,Palmer,AC.: :
Episodic falling in the cavalier King Charles spaniel. Vet Rec 112:458-9, 1983.
Pubmed reference: 6868317 .
1969 Meyers,K.M.,Lund,J.E.,Padgett,G.A.: :
Hyperkinetic episodes in Scottish Terrier dogs Journal of the American Veterinary Medical Association 155:124-133, 1969.
Pubmed reference: 5816228 .