The detail information of Haemangiosarcoma
OMIA Basic Information

Possible human homologues (MIM numbers):

Mendelian trait/disorder: unknown

Mode of inheritance: -

Considered a defect: yes

Year key mutation first reported: -

Species-specific name: -

Species-specific symbol: -

More detail information can see in

Associated Breeds
There are associated breeds.
Associated Gene
There are no associated genes.
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 Evans,J.M.,Parker,H.G.,Rutteman,G.R.,Plassais,J.,Grinwis,G.C.M.,Harris,A.C.,Lana,S.E.,Ostrander,E.A.: :
Multi-omics approach identifies germline regulatory variants associated with hematopoietic malignancies in retriever dog breeds. PLoS Genet 17:e1009543, 2021.
Pubmed reference: 33983928 . DOI: 10.1371/journal.pgen.1009543 .
2016 Anwar,S.h.,Yanai,T.,Sakai,H.: :
Overexpression of Peroxiredoxin 6 Protects Neoplastic Cells against Apoptosis in Canine Haemangiosarcoma. J Comp Pathol 155:29-39, 2016.
Pubmed reference: 27306414 . DOI: 10.1016/j.jcpa.2016.05.002 .
2016 Yoo,S.,Kim,J.,Myung,H.W.,Woo,S.,Chung,D.J.,Lee,A.J.,Kim,H.J.,DO,S.H.,Kim,H.Y.: :
Primary intrapelvic hemangiosarcoma in a dog. J Vet Med Sci :, 2016.
Pubmed reference: 27746404 . DOI: 10.1292/jvms.16-0186 .
2015 Tonomura,N.,Elvers,I.,Thomas,R.,Megquier,K.,Turner-Maier,J.,Howald,C.,Sarver,A.L.,Swofford,R.,Frantz,A.M.,Ito,D.,Mauceli,E.,Arendt,M.,Noh,H.J.,Koltookian,M.,Biagi,T.,Fryc,S.,Williams,C.,Avery,A.C.,Kim,J.H.,Barber,L.,Burgess,K.,Lander,E.S.,Karlsson,E.K.,Azuma,C.,Modiano,J.F.,Breen,M.,Lindblad-Toh,K.: :
Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers. PLoS Genet 11:e1004922, 2015.
Pubmed reference: 25642983 . DOI: 10.1371/journal.pgen.1004922 .
2014 Thomas,R.,Borst,L.,Rotroff,D.,Motsinger-Reif,A.,Lindblad-Toh,K.,Modiano,J.F.,Breen,M.: :
Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma. Chromosome Res :, 2014.
Pubmed reference: 24599718 . DOI: 10.1007/s10577-014-9406-z .
2013 Alvarez,F.J.,Hosoya,K.,Lara-Garcia,A.,Kisseberth,W.,Couto,G.: :
VAC Protocol for Treatment of Dogs with Stage III Hemangiosarcoma. J Am Anim Hosp Assoc :, 2013.
Pubmed reference: 24051260 . DOI: 10.5326/JAAHA-MS-5954 .
2013 Bellumori,T.P.,Famula,T.R.,Bannasch,D.L.,Belanger,J.M.,Oberbauer,A.M.: :
Prevalence of inherited disorders among mixed-breed and purebred dogs: 27,254 cases (1995-2010). J Am Vet Med Assoc 242:1549-55, 2013.
Pubmed reference: 23683021 . DOI: 10.2460/javma.242.11.1549 .
2013 Dobson,J.M.: :
Breed-predispositions to cancer in pedigree dogs. ISRN Vet Sci 2013:941275, 2013.
Pubmed reference: 23738139 . DOI: 10.1155/2013/941275 .
2013 Tsuji,N.,Furukawa,S.,Ozaki,K.: :
Cutaneous hemangiosarcoma in a dog. J Toxicol Pathol 26:193-5, 2013.
Pubmed reference: 23914061 . DOI: 10.1293/tox.26.193 .
2013 Yamamoto,S.,Hoshi,K.,Hirakawa,A.,Chimura,S.,Kobayashi,M.,Machida,N.: :
Epidemiological, Clinical and Pathological Features of Primary Cardiac Hemangiosarcoma in Dogs: A Review of 51 Cases. J Vet Med Sci :, 2013.
Pubmed reference: 23811814 .
2012 Asa,S.A.,Murai,A.,Murakami,M.,Hoshino,Y.,Mori,T.,Maruo,K.,Khater,A.,El-Sawak,A.,el-Aziz,E.A.,Yanai,T.,Sakai,H.: :
Expression of platelet-derived growth factor and its receptors in spontaneous canine hemangiosarcoma and cutaneous hemangioma. Histol Histopathol 27:601-7, 2012.
Pubmed reference: 22419024 .
2012 Guinan,J.,Fischetti,A.,Garate,A.P.,Chalhoub,S.: :
Primary peri-aortic hemangiosarcoma in a dog. Can Vet J 53:1214-8, 2012.
Pubmed reference: 23633719 .
2011 Haeussler,D.J.,Rodríguez,L.M.,Wilkie,D.A.,Premanandan,C.: :
Primary central corneal hemangiosarcoma in a dog. Vet Ophthalmol 14:133-6, 2011.
Pubmed reference: 21366830 . DOI: 10.1111/j.1463-5224.2010.00849.x .
2011 Mun,A.,Lee,E.M.,Kim,A.Y.,Lee,E.J.,Hong,I.H.,Jeong,K.S.: :
Canine hemangiosarcoma in a female Jindo dog. Lab Anim Res 27:361-3, 2011.
Pubmed reference: 22232648 . DOI: 10.5625/lar.2011.27.4.361 .
2011 Shiu,K.B.,Flory,A.B.,Anderson,C.L.,Wypij,J.,Saba,C.,Wilson,H.,Kurzman,I.,Chun,R.: :
Predictors of outcome in dogs with subcutaneous or intramuscular hemangiosarcoma. J Am Vet Med Assoc 238:472-9, 2011.
Pubmed reference: 21320017 . DOI: 10.2460/javma.238.4.472 .
2010 Fawcett,A.,Phillips,A.,Billson,M.: :
Ocular hemangiosarcoma in a husky. Compend Contin Educ Vet 32:E8, 2010.
Pubmed reference: 23705189 .
2010 Tamburini,B.A.,Phang,T.L.,Fosmire,S.P.,Scott,M.C.,Trapp,S.C.,Duckett,M.M.,Robinson,S.R.,Slansky,J.E.,Sharkey,L.C.,Cutter,G.R.,Wojcieszyn,J.W.,Bellgrau,D.,Gemmill,R.M.,Hunter,L.E.,Modiano,J.F.: :
Gene expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma. BMC Cancer 10:619, 2010.
Pubmed reference: 21062482 . DOI: 10.1186/1471-2407-10-619 .
2009 Tamburini,B.A.,Trapp,S.,Phang,T.L.,Schappa,J.T.,Hunter,L.E.,Modiano,J.F.: :
Gene expression profiles of sporadic canine hemangiosarcoma are uniquely associated with breed. PLoS One 4:e5549, 2009.
Pubmed reference: 19461996 . DOI: 10.1371/journal.pone.0005549 .
2007 Sargan,D.: :
Haemangiosarcoma in German shepherd dogs. Vet Rec 160:672, 2007.
Pubmed reference: 17496285 .
2007 Yonemaru,K.,Sakai,H.,Murakami,M.,Kodama,A.,Mori,T.,Yanai,T.,Maruo,K.,Masegi,T.: :
The significance of p53 and retinoblastoma pathways in canine hemangiosarcoma. J Vet Med Sci 69:271-8, 2007.
Pubmed reference: 17409643 .
2006 Lamerato-Kozicki,A.R.,Helm,K.M.,Jubala,C.M.,Cutter,G.C.,Modiano,J.F.: :
Canine hemangiosarcoma originates from hematopoietic precursors with potential for endothelial differentiation. Exp Hematol 34:870-8, 2006.
Pubmed reference: 16797414 . DOI: 10.1016/j.exphem.2006.04.013 .
2005 Dickerson,E.B.,Thomas,R.,Fosmire,S.P.,Lamerato-Kozicki,A.R.,Bianco,S.R.,Wojcieszyn,J.W.,Breen,M.,Helfand,S.C.,Modiano,J.F.: :
Mutations of phosphatase and tensin homolog deleted from chromosome 10 in canine hemangiosarcoma. Vet Pathol 42:618-32, 2005.
Pubmed reference: 16145208 . DOI: 10.1354/vp.42-5-618 .
2004 Fosmire,S.P.,Dickerson,E.B.,Scott,A.M.,Bianco,S.R.,Pettengill,M.J.,Meylemans,H.,Padilla,M.,Frazer-Abel,A.A.,Akhtar,N.,Getzy,D.M.,Wojcieszyn,J.,Breen,M.,Helfand,S.C.,Modiano,J.F.: :
Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium. Lab Invest 84:562-72, 2004.
Pubmed reference: 15064773 . DOI: 10.1038/labinvest.3700080 .
2004 Schultheiss,P.C.: :
A retrospective study of visceral and nonvisceral hemangiosarcoma and hemangiomas in domestic animals. J Vet Diagn Invest 16:522-6, 2004.
Pubmed reference: 15586567 .
2003 Smith,A.N.: :
Hemangiosarcoma in dogs and cats. Vet Clin North Am Small Anim Pract 33:533-52, vi, 2003.
Pubmed reference: 12852235 .
2002 Mayr,B.,Zwetkoff,S.,Schaffner,G.,Reifinger,M.: :
Tumour suppressor gene p53 mutation in a case of haemangiosarcoma of a dog. Acta Vet Hung 50:157-60, 2002.
Pubmed reference: 12113170 . DOI: 10.1556/AVet.50.2002.2.4 .
2001 Clifford,C.A.,Hughes,D.,Beal,M.W.,Mackin,A.J.,Henry,C.J.,Shofer,F.S.,Sorenmo,K.U.: :
Plasma vascular endothelial growth factor concentrations in healthy dogs and dogs with hemangiosarcoma. J Vet Intern Med 15:131-5, 2001.
Pubmed reference: 11300596 .
1998 Wood,C.A.,Moore,A.S.,Gliatto,J.M.,Ablin,L.A.,Berg,R.J.,Rand,W.M.: :
Prognosis for dogs with stage I or II splenic hemangiosarcoma treated by splenectomy alone: 32 cases (1991-1993). J Am Anim Hosp Assoc 34:417-21, 1998.
Pubmed reference: 9728473 .
1994 Ward,H.,Fox,L.E.,Calderwood-Mays,M.B.,Hammer,A.S.,Couto,C.G.: :
Cutaneous hemangiosarcoma in 25 dogs: a retrospective study. J Vet Intern Med 8:345-8, 1994.
Pubmed reference: 7837111 .
1985 Aronsohn,M.: :
Cardiac hemangiosarcoma in the dog: a review of 38 cases. J Am Vet Med Assoc 187:922-6, 1985.
Pubmed reference: 4055516 .
1985 Brown,N.O.,Patnaik,A.K.,MacEwen,E.G.: :
Canine hemangiosarcoma: retrospective analysis of 104 cases. J Am Vet Med Assoc 186:56-8, 1985.
Pubmed reference: 4038395 .
1985 Ng,C.Y.,Mills,J.N.: :
Clinical and haematological features of haemangiosarcoma in dogs. Aust Vet J 62:1-4, 1985.
Pubmed reference: 4039924 .
1978 Oksanen,A.: :
Haemangiosarcoma in dogs. J Comp Pathol 88:585-95, 1978.
Pubmed reference: 568633 .