The detail information of Hydrocephalus
Basic Information

Disease Description: A condition where there is an abnormal accumulation of fluid in the ventricles of the brain.

Inherit Mode: The mode of inheritance is unknown, but there is a predisposition to this condition in the breeds listed below.

Disease Symptom: Puppies with severe hydrocephalus often die at a very early age due to pressure from the increased fluid in the brain. In other less severely affected pups, the signs gradually become apparent over the first few months of life, and in some mild cases the condition is only diagnosed later in life. The types of signs seen with this condition include lack of thriftiness (smaller than littermates, slow to grow), a domed skull (which gradually becomes more pronounced), abnormal movement behaviour (e.g., restlessness, aimless walking), problems with vision, and seizures. These pups are very slow to learn - it may be extremely difficult to housetrain them for example, or they may lose their housetraining. Generally the signs gradually worsen, although by 2 years of age they may stabilize. To minimize brain damage, the condition must be recognized and appropriate treatment begun early. However, affected animals will likely always be slow and have a limited ability to learn.

Disease Cause: -

Disease Diagnose: Hydrocephalus can be difficult to diagnose. Your veterinarian will consider the combination of physical, behavioural and neurological abnormalities in your dog. The diagnosis can be confirmed by MRI or CT scanning, or by ultrasonography in some cases.

Treat Method: There are various drugs that may be used to decrease cerebrospinal fluid production. Treatment often needs to be repeated, although some dogs will stabilize by about 2 years of age. If no improvement is seen within a few weeks of beginning medical treatment, your veterinarian may suggest surgical implantation of a shunt to drain the CSF. Affected dogs are susceptible to other medical problems and may have a poor tolerance to various drugs. Antiepileptic drugs may be used for control of seizures. Depending on the severity of the clinical signs, and recognizing the ongoing medical problems these dogs may face, your veterinarian will likely discuss with you humane euthanasia as another option for your pup.

Breeder Advice: Affected animals should not be bred. Even though little is known about the heritability of this condition, it is also preferable to avoid breeding dogs who are unaffected but have a familial history of hydrocephalus.

Disease Description Source: Link

Associated Diseases
Disease Name Other Name Mode of inheritance Link ID Possible OMIM ID Gene
Hydrocephalus - - -
Associated Breeds
iDog Breed Number Breed Name Personality Height Weight Breed Source
CB46 Boston Terrier Friendly, bright, amusing, and adaptable. 38.1-43.2 cm 4.5-11.3 kg United States
CB47 Bouvier des Flandres(Flanders Cattle Dog) Strong-willed, even-tempered, courageous; affectionate with family, intimidating to intruders 62.2-69.9 cm (male), 59.7-67.3 cm (female) 31.8-49.9 kg Belgium
CB58 English Bulldog Calm, courageous, and friendly; dignified but amusing. 35.6-38.1 cm 22.7 kg (male), 18.1 kg (female) United Kingdom (England)
CB60 Cairn Terrier Cheerful, alert, busy and independent-minded 25.4 cm (male), 24.1 cm (female) 6.4 kg (male), 5.9 kg (female) United Kingdom (Scotland)
CB71 Chihuahua Graceful, charming, and sassy. 15.2-22.9 cm 1.4-2.7 kg Mexico
CB72 Chinese Crested Lively, alert, and affectionate 27.9-33 cm 3.6-5.4 kg Africa, Mexico
CB78 Cocker Spaniel Happy, smart, gentle 36.8-39.4 cm (male), 34.3-36.8 cm (female) 11.3-13.6 kg (male), 9.1-11.3 kg (female)
CB98 English Toy Spaniel Affectionate, Alert, Merry 22.9-25.4 cm 3.6-6.4 kg England
CB153 Lhasa Apso(Long-Haired Lhasa Dog) Smart, confident, complex; a family comedian, but regally aloof with strangers 25.4-27.9 cm (male), slightly smaller (female) 5.4-8.2 kg Tibet
CB155 Maltese Gentle, playful, affectionate; fearless in a charming toy-dog way. 20.3-25.4 cm 2.7-3.6 kg Italy
CB156 Manchester Terrier Spirited, bright, keenly observant; dead loyal, in an independent terrier way 38.1-40.6 cm 5.4-10 kg (standard) United Kingdom (England)
CB178 Pekingese Affectionate, loyal, regal in manner 15.2-22.9 cm up to 6.4 kg China
CB187 Pomeranian Inquisitive, Bold, Lively 15.2-17.8 cm 1.4-3.2 kg Germany, Poland
CB218 Shih Tzu(Chrysanthemum Dog) Outgoing, affectionate, playful and charming 20.3-27.9 cm 4.1-7.3 kg China
CB222 Skye Terrier Plucky but dignified, calm but sometimes stubborn; famously loyal and devoted 25.4 cm (male), 24.1 cm (female) 15.9-20.4 kg (male), slightly lighter (female) United Kingdom (Scotland)
CB262 Yorkshire Terrier Sprightly, tomboyish, and affectionate 17.8-20.3 cm 3.2 kg United Kingdom (England)
CB263 Akbash Dog Calm, quiet, and steady.,independent ,loyal, gentle, and quietly affectionate with its own family, including children and family pets, but remains aloof and suspicious toward strangers. 76.2-86.4 cm (male), 71.1-81.3 cm (female) 54.4 kg (male), 40.8 kg (female) Turkey
CB270 Toy Poodle Intelligent, eager to please, quick to learn and an affectionate, loyal pet. under 25 cm
References
2010 Thomas,WB.: :
Hydrocephalus in dogs and cats. Vet Clin North Am Small Anim Pract 40:143-59, 2010.
Pubmed reference: 19942061 . DOI: 10.1016/j.cvsm.2009.09.008 .
2008 Kitagawa,M.,Ueno,H.,Watanabe,S.,Igarashi,O.,Uzuka,Y.,Kanayama,K.,Sakai,T.: :
Clinical improvement in two dogs with hydrocephalus and syringohydromyelia after ventriculoperitoneal shunting. Aust Vet J 86:36-42, 2008.
Pubmed reference: 18271823 . DOI: 10.1111/j.1751-0813.2007.00247.x .
2007 Coates JR. :
Hydrodephalus Côté E, ed. Clinical Veterinary Advisor Dogs and Cats Missouri: Mosby Elsevier, 2007:534-535.
1999 Ackerman, L. :
The Genetic Condition: A Guide to Health Problems in Purebred Dogs AAHA Press. Lakewood, Colorado. pp 135-136
1997 Cantile,C.,Arispici,M.,Modenato,M.,Fatzer,R.: :
Hydrocephalus with periventricular encephalitis in the dog Zentralblatt Fur Veterinarmedizin - Reihe A 44:595-601, 1997.
Pubmed reference: 9465779 .
1996 Itoh,T.,Nishimura,R.,Matsunaga,S.,Kodosawa,T.,Mochizuki,M.,Sasaki,N.: :
Syringomyelia and hydrocephalus in a dog Journal of the American Veterinary Medical Association 209:934 ff., 1996.
1996 Jones,B.R.,Alley,M.R.,Batchelor,B.: :
Hydrocephalus and hypertrichosis in Golden Retriever dogs New Zealand Veterinary Journal 44:38-39, 1996.
1993 Brunetti,A.,Fatone,G.,Cuomo,A.,Lorizio,R.,Potena,A.: :
Meningomyelocele and Hydrocephalus in a Bulldog Progress in Veterinary Neurology 4:54-59, 1993.