Leaf Senescence DataBase

Basic information

Locus name

AT5G14930

Alias

SAG101

Organism

Arabidopsis thaliana

Taxonomic identifier

[NCBI]

Function category

Nutrient recycling

Effect for Senescence

promote

Gene Description

encodes an acyl hydrolase involved in senescence

Evidence

Genetic evidence:Transgene and mutant [Ref 1]

References

1: He Y, Gan S
A gene encoding an acyl hydrolase is involved in leaf senescence in Arabidopsis.
Plant Cell 2002 Apr;14(4):805-15

2: Feys BJ, Wiermer M, Bhat RA, Moisan LJ, Medina-Escobar N, Neu C, Cabral A, Parker JE
Arabidopsis SENESCENCE-ASSOCIATED GENE101 stabilizes and signals within an ENHANCED DISEASE SUSCEPTIBILITY1 complex in plant innate immunity.
Plant Cell 2005 Sep;17(9):2601-13

3: Wiermer M, Feys BJ, Parker JE
Plant immunity: the EDS1 regulatory node.
Curr. Opin. Plant Biol. 2005 Aug;8(4):383-9

4: Lipka V, Dittgen J, Bednarek P, Bhat R, Wiermer M, Stein M, Landtag J, Brandt W, Rosahl S, Scheel D, Llorente F, Molina A, Parker J, Somerville S, Schulze-Lefert P
Pre- and postinvasion defenses both contribute to nonhost resistance in Arabidopsis.
Science 2005 Nov 18;310(5751):1180-3

5: Pegadaraju V, Louis J, Singh V, Reese JC, Bautor J, Feys BJ, Cook G, Parker JE, Shah J
Phloem-based resistance to green peach aphid is controlled by Arabidopsis PHYTOALEXIN DEFICIENT4 without its signaling partner ENHANCED DISEASE SUSCEPTIBILITY1.
Plant J. 2007 Oct;52(2):332-41

6: Kim CY, Bove J, Assmann SM
Overexpression of wound-responsive RNA-binding proteins induces leaf senescence and hypersensitive-like cell death.
New Phytol. 2008;180(1):57-70

7: Ay N, Irmler K, Fischer A, Uhlemann R, Reuter G, Humbeck K
Epigenetic programming via histone methylation at WRKY53 controls leaf senescence in Arabidopsis thaliana.
Plant J. 2009 Apr;58(2):333-46

8: Venugopal SC, Jeong RD, Mandal MK, Zhu S, Chandra-Shekara AC, Xia Y, Hersh M, Stromberg AJ, Navarre D, Kachroo A, Kachroo P
Enhanced disease susceptibility 1 and salicylic acid act redundantly to regulate resistance gene-mediated signaling.
PLoS Genet. 2009 Jul;5(7):e1000545

Gene Ontology

biological process	lipid metabolic process
molecular function	triglyceride lipase activity

Pathway

Reactome

Sequence

Mutant information

Mutated 1
	Mutant name	SAG101 antisense line
	Mutant/Transgenic	transgenic
	Ecotype	Col-gl1
	Mutagenesis type	antisense

Mutated 2
	Mutant name	Inducible SAG101 overexpression line
	Mutant/Transgenic	transgenic
	Ecotype	Col-gl1
	Mutagenesis type	transgene

miRNA Interaction

Details

target: AT5G14930.2
miRNA: ath-miR395a
miRNA: ath-miR395a
mfe: -29.4 kcal/mol
p-value: 0.006867

position:  497
target 5' A     G              A 3'
           GAGUU CUCCAAACGCU CA
           CUCAA GGGGUUUGUGA GU
miRNA  3'       G           A  C 5'

target: AT5G14930.2
miRNA: ath-miR395b
miRNA: ath-miR395b
mfe: -29.8 kcal/mol
p-value: 0.017888

position:  497
target 5' A     G              A 3'
           GAGUU CUCCAAACGCU CA
           CUCAG GGGGUUUGUGA GU
miRNA  3'       G           A  C 5'

target: AT5G14930.2
miRNA: ath-miR395c
miRNA: ath-miR395c
mfe: -29.8 kcal/mol
p-value: 0.012591

position:  497
target 5' A     G              A 3'
           GAGUU CUCCAAACGCU CA
           CUCAG GGGGUUUGUGA GU
miRNA  3'       G           A  C 5'

target: AT5G14930.2
miRNA: ath-miR395d
miRNA: ath-miR395d
mfe: -29.4 kcal/mol
p-value: 0.010443

position:  497
target 5' A     G              A 3'
           GAGUU CUCCAAACGCU CA
           CUCAA GGGGUUUGUGA GU
miRNA  3'       G           A  C 5'

target: AT5G14930.2
miRNA: ath-miR395e
miRNA: ath-miR395e
mfe: -29.4 kcal/mol
p-value: 0.007916

position:  497
target 5' A     G              A 3'
           GAGUU CUCCAAACGCU CA
           CUCAA GGGGUUUGUGA GU
miRNA  3'       G           A  C 5'

target: AT5G14930.2
miRNA: ath-miR395f
miRNA: ath-miR395f
mfe: -29.8 kcal/mol
p-value: 0.015773

position:  497
target 5' A     G              A 3'
           GAGUU CUCCAAACGCU CA
           CUCAG GGGGUUUGUGA GU
miRNA  3'       G           A  C 5'

target: AT5G14930.3
miRNA: ath-miR395a
miRNA: ath-miR395a
mfe: -29.4 kcal/mol
p-value: 0.004846

position:  498
target 5' A     G              A 3'
           GAGUU CUCCAAACGCU CA
           CUCAA GGGGUUUGUGA GU
miRNA  3'       G           A  C 5'

target: AT5G14930.3
miRNA: ath-miR395b
miRNA: ath-miR395b
mfe: -29.8 kcal/mol
p-value: 0.013799

position:  498
target 5' A     G              A 3'
           GAGUU CUCCAAACGCU CA
           CUCAG GGGGUUUGUGA GU
miRNA  3'       G           A  C 5'

target: AT5G14930.3
miRNA: ath-miR395c
miRNA: ath-miR395c
mfe: -29.8 kcal/mol
p-value: 0.009103

position:  498
target 5' A     G              A 3'
           GAGUU CUCCAAACGCU CA
           CUCAG GGGGUUUGUGA GU
miRNA  3'       G           A  C 5'

target: AT5G14930.3
miRNA: ath-miR395d
miRNA: ath-miR395d
mfe: -29.4 kcal/mol
p-value: 0.008071

position:  498
target 5' A     G              A 3'
           GAGUU CUCCAAACGCU CA
           CUCAA GGGGUUUGUGA GU
miRNA  3'       G           A  C 5'

target: AT5G14930.3
miRNA: ath-miR395e
miRNA: ath-miR395e
mfe: -29.4 kcal/mol
p-value: 0.005708

position:  498
target 5' A     G              A 3'
           GAGUU CUCCAAACGCU CA
           CUCAA GGGGUUUGUGA GU
miRNA  3'       G           A  C 5'

target: AT5G14930.3
miRNA: ath-miR395f
miRNA: ath-miR395f
mfe: -29.8 kcal/mol
p-value: 0.011848

position:  498
target 5' A     G              A 3'
           GAGUU CUCCAAACGCU CA
           CUCAG GGGGUUUGUGA GU
miRNA  3'       G           A  C 5'

Ortholog Group

Ortholog Groups: OG5_177347

Accession	Taxon
NP_001078585	Arabidopsis thaliana
NP_568307 ( AT5G14930 )	Arabidopsis thaliana
NP_851039	Arabidopsis thaliana
29822.m003400	Ricinus communis

Cross Link

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF01764	4.5E-12	114	203	IPR002921	Lipase, class 3
PANTHER	PTHR32013	3.3E-12	124	203	No hit	NA
SUPERFAMILY	SSF53474	4.6E-11	124	204	No hit	NA