Basic information
Locus name	AT3G13380
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification
Effect for Senescence	unclear
Gene Description	leucine-rich repeat family protein / protein kinase family protein contains Pfam domains PF00560: Leucine Rich Repeat and PF00069: Protein kinase domain
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process protein phosphorylation molecular function ATP binding protein binding protein kinase activity protein serine/threonine kinase activity
Sequence	AT3G13380.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT3G13380.1  miRNA: ath-miR399e miRNA: ath-miR399e mfe: -26.4 kcal/mol  p-value: 0.039850  position:  1426  target 5' U       C     C      C 3'             GAGGCAG UCUCU UUG CA              CUCCGUU AGAGG AAC GU   miRNA  3' G       U     A   C    5'  target: AT3G13380.1  miRNA: ath-miR779 miRNA: ath-miR779 mfe: -22.1 kcal/mol  p-value: 0.085141  position:  1307  target 5' C                     G 3'             GG CGAC AGAUUUCCGGUUA              UC GUUG UUUAAAGGUUAGU   miRNA  3'    A    C               5'  target: AT3G13380.1  miRNA: ath-miR780 miRNA: ath-miR780 mfe: -28.0 kcal/mol  p-value: 0.050570  position:  3040  target 5' C     G        A      A 3'             AUCUG U AGCAGC GCUGGA              UGGAC A UUGUCG CGAUCU   miRNA  3'       G G      A        5'  target: AT3G13380.1  miRNA: ath-miR837-5p miRNA: ath-miR837-5p mfe: -22.1 kcal/mol  p-value: 0.198719  position:  3235  target 5' U  U     U            U 3'             UG AGCGA CAAGAAGUUGAU              AC UUGCU GUUCUUUGACUA   miRNA  3'    U     U              5'  target: AT3G13380.1  miRNA: ath-miR858 miRNA: ath-miR858 mfe: -25.7 kcal/mol  p-value: 0.068556  position:  2358  target 5' G     G        U  A    U 3'             AAGGU GGACGGAU GC GAGG              UUCCA CUUGUCUG UG CUUU   miRNA  3'       G        U         5'
Ortholog Group
Ortholog Groups: OG5_127136	Accession Taxon NP_001032080 Arabidopsis thaliana NP_001117501 Arabidopsis thaliana NP_001117591 Arabidopsis thaliana NP_172335 Arabidopsis thaliana NP_172468 Arabidopsis thaliana NP_173166 Arabidopsis thaliana NP_173217 Arabidopsis thaliana NP_174166 Arabidopsis thaliana NP_174673 Arabidopsis thaliana NP_174809 Arabidopsis thaliana NP_175957 Arabidopsis thaliana NP_177363 Arabidopsis thaliana NP_177451 Arabidopsis thaliana NP_177710 Arabidopsis thaliana NP_178304 Arabidopsis thaliana NP_180875 Arabidopsis thaliana NP_187946 ( AT3G13380 ) Arabidopsis thaliana NP_188604 Arabidopsis thaliana NP_189066 Arabidopsis thaliana NP_190536 Arabidopsis thaliana NP_192625 Arabidopsis thaliana NP_193747 Arabidopsis thaliana NP_193760 Arabidopsis thaliana NP_194578 Arabidopsis thaliana NP_194594 Arabidopsis thaliana NP_195650 Arabidopsis thaliana NP_196345 Arabidopsis thaliana NP_197965 Arabidopsis thaliana NP_199283 Arabidopsis thaliana NP_199705 Arabidopsis thaliana NP_199777 Arabidopsis thaliana NP_199948 Arabidopsis thaliana NP_200415 Arabidopsis thaliana NP_200956 Arabidopsis thaliana NP_201198 Arabidopsis thaliana NP_201371 Arabidopsis thaliana NP_201372 Arabidopsis thaliana NP_567748 Arabidopsis thaliana NP_849538 Arabidopsis thaliana NP_850942 Arabidopsis thaliana 120925 Chlamydomonas reinhardtii ACO66850 Micromonas sp. RCC299 NP_001042139 Oryza sativa Japonica Group NP_001042546 Oryza sativa Japonica Group NP_001044077 Oryza sativa Japonica Group NP_001044213 Oryza sativa Japonica Group NP_001044979 Oryza sativa Japonica Group NP_001045202 Oryza sativa Japonica Group NP_001045656 Oryza sativa Japonica Group NP_001046354 Oryza sativa Japonica Group NP_001046355 Oryza sativa Japonica Group NP_001047110 Oryza sativa Japonica Group NP_001048946 Oryza sativa Japonica Group NP_001049453 Oryza sativa Japonica Group NP_001051418 Oryza sativa Japonica Group NP_001052097 Oryza sativa Japonica Group NP_001054764 Oryza sativa Japonica Group NP_001054768 Oryza sativa Japonica Group NP_001056517 Oryza sativa Japonica Group NP_001057858 Oryza sativa Japonica Group NP_001057860 Oryza sativa Japonica Group NP_001057964 Oryza sativa Japonica Group NP_001058593 Oryza sativa Japonica Group NP_001058840 Oryza sativa Japonica Group NP_001058906 Oryza sativa Japonica Group NP_001059710 Oryza sativa Japonica Group NP_001061677 Oryza sativa Japonica Group NP_001061926 Oryza sativa Japonica Group NP_001062124 Oryza sativa Japonica Group NP_001062792 Oryza sativa Japonica Group NP_001062883 Oryza sativa Japonica Group NP_001064047 Oryza sativa Japonica Group NP_001064062 Oryza sativa Japonica Group NP_001064813 Oryza sativa Japonica Group NP_001064816 Oryza sativa Japonica Group NP_001064819 Oryza sativa Japonica Group NP_001065120 Oryza sativa Japonica Group NP_001067347 Oryza sativa Japonica Group NP_001067348 Oryza sativa Japonica Group NP_001067561 Oryza sativa Japonica Group NP_001067562 Oryza sativa Japonica Group e_gw1.11.00.101.1 Ostreococcus tauri e_gw1.14.30.1 Physcomitrella patens subsp. patens e_gw1.14.67.1 Physcomitrella patens subsp. patens e_gw1.161.14.1 Physcomitrella patens subsp. patens e_gw1.172.6.1 Physcomitrella patens subsp. patens e_gw1.182.5.1 Physcomitrella patens subsp. patens e_gw1.244.2.1 Physcomitrella patens subsp. patens e_gw1.281.94.1 Physcomitrella patens subsp. patens e_gw1.5.384.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_1110048 Physcomitrella patens subsp. patens estExt_Genewise1.C_680049 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_1780069 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2120003 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_480110 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_247000007 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_63000078 Physcomitrella patens subsp. patens gw1.102.8.1 Physcomitrella patens subsp. patens 27837.m000161 Ricinus communis 27893.m000225 Ricinus communis 27956.m000355 Ricinus communis 27985.m000860 Ricinus communis 28644.m000896 Ricinus communis 28830.m000232 Ricinus communis 28830.m000234 Ricinus communis 28966.m000525 Ricinus communis 29592.m000104 Ricinus communis 29637.m000755 Ricinus communis 29666.m001469 Ricinus communis 29680.m001721 Ricinus communis 29680.m001748 Ricinus communis 29737.m001253 Ricinus communis 29765.m000745 Ricinus communis 29780.m001387 Ricinus communis 29794.m003413 Ricinus communis 29904.m002997 Ricinus communis 29904.m003011 Ricinus communis 29908.m006021 Ricinus communis 29912.m005436 Ricinus communis 29983.m003126 Ricinus communis 30074.m001369 Ricinus communis 30099.m001625 Ricinus communis 30147.m013904 Ricinus communis 30147.m013919 Ricinus communis 30147.m014235 Ricinus communis 30147.m014245 Ricinus communis 30147.m014283 Ricinus communis 30158.m000501 Ricinus communis 30170.m013627 Ricinus communis 30170.m013628 Ricinus communis 30170.m013629 Ricinus communis 30170.m014376 Ricinus communis 30190.m011299 Ricinus communis 30204.m001801 Ricinus communis 51128.m000015 Ricinus communis estExt_thaps1_ua_kg.C_chr_40298 Thalassiosira pseudonana CCMP1335 XP_002948176 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description Pfam PF08263 2.5E-7 33 73 IPR013210 Leucine-rich repeat-containing N-terminal, type 2 SUPERFAMILY SSF52047 4.7E-51 81 397 No hit NA SMART SM00369 12.0 100 123 IPR003591 Leucine-rich repeat, typical subtype Pfam PF13855 7.5E-8 101 162 No hit NA SMART SM00369 260.0 124 148 IPR003591 Leucine-rich repeat, typical subtype Pfam PF13516 1.0 174 193 No hit NA Pfam PF00560 0.1 202 220 IPR001611 Leucine-rich repeat PANTHER PTHR24420 0.0 232 1161 No hit NA SMART SM00369 410.0 301 324 IPR003591 Leucine-rich repeat, typical subtype Pfam PF13855 8.0E-9 303 363 No hit NA SUPERFAMILY SSF52047 2.5E-56 344 569 No hit NA SMART SM00369 240.0 374 398 IPR003591 Leucine-rich repeat, typical subtype Pfam PF00560 0.0 376 398 IPR001611 Leucine-rich repeat Pfam PF13855 1.1E-6 404 462 No hit NA SMART SM00369 130.0 475 498 IPR003591 Leucine-rich repeat, typical subtype SMART SM00369 56.0 522 546 IPR003591 Leucine-rich repeat, typical subtype Pfam PF13516 0.2 546 568 No hit NA SUPERFAMILY SSF52047 2.5E-56 638 725 No hit NA SMART SM00369 99.0 662 685 IPR003591 Leucine-rich repeat, typical subtype Pfam PF13855 1.5E-9 665 723 No hit NA SMART SM00369 33.0 686 709 IPR003591 Leucine-rich repeat, typical subtype SUPERFAMILY SSF56112 9.7E-76 839 1132 IPR011009 Protein kinase-like domain ProSiteProfiles PS50011 38.7 858 1136 IPR000719 Protein kinase, catalytic domain SMART SM00220 9.1E-35 858 1136 IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain Pfam PF00069 7.4E-44 861 1130 IPR000719 Protein kinase, catalytic domain ProSitePatterns PS00107 NA 864 887 IPR017441 Protein kinase, ATP binding site ProSitePatterns PS00108 NA 981 993 IPR008271 Serine/threonine-protein kinase, active site
Subcellular Localization
Localization	plasma membrane
Evidence	SUBAcon
Pubmed ID	23180787