Basic information
Locus name	AT2G33150
Alias	PED1/KAT2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Hormone response pathway:JA
Effect for Senescence	promote
Gene Description	The KAT2 activation associated with dark-induced senescence occurred soon after a move to darkness, and it preceded the detection of symptoms and the expression of senescence-associated gene (SAG) markers. Transgenic plants with reduced expression of the KAT2 gene showed a significant delayed senescence both in natural and dark-induced processes.
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Castillo MC, Leon J Expression of the beta-oxidation gene 3-ketoacyl-CoA thiolase 2 (KAT2) is required for the timely onset of natural and dark-induced leaf senescence in Arabidopsis. J. Exp. Bot. 2008;59(8):2171-9
Gene Ontology	biological process metabolic process molecular function transferase activity, transferring acyl groups other than amino-acyl groups
Pathway	Reactome REACT_22258
Sequence	AT2G33150.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name KAT2as Mutant/Transgenic transgenic Ecotype Col-0 Mutagenesis type RNAi
Mutated 2 Mutant name KAT2ox Mutant/Transgenic transgenic Ecotype Col-0 Mutagenesis type transgene
Ortholog Group
Ortholog Groups: OG5_128333	Accession Taxon NP_001032037 Arabidopsis thaliana NP_171965 Arabidopsis thaliana NP_180873 ( AT2G33150 ) Arabidopsis thaliana NP_568704 Arabidopsis thaliana NP_851157 Arabidopsis thaliana 138637 Chlamydomonas reinhardtii ACO61553 Micromonas sp. RCC299 NP_001048523 Oryza sativa Japonica Group NP_001064764 Oryza sativa Japonica Group e_gw1.06.00.191.1 Ostreococcus tauri e_gw1.55.167.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_670017 Physcomitrella patens subsp. patens 29904.m002984 Ricinus communis 30204.m001789 Ricinus communis e_gw1.11a.55.1 Thalassiosira pseudonana CCMP1335 XP_002946078 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR18919 4.5E-291 1 440 IPR002155 Thiolase SUPERFAMILY SSF53901 5.0E-69 44 309 IPR016039 Thiolase-like Pfam PF00108 2.5E-83 50 307 IPR020616 Thiolase, N-terminal TIGRFAM TIGR01930 4.4E-138 54 437 IPR002155 Thiolase ProSitePatterns PS00098 NA 134 152 IPR020615 Thiolase, acyl-enzyme intermediate active site Pfam PF02803 1.2E-48 315 438 IPR020617 Thiolase, C-terminal SUPERFAMILY SSF53901 8.2E-41 317 438 IPR016039 Thiolase-like ProSitePatterns PS00737 NA 383 399 IPR020613 Thiolase, conserved site ProSitePatterns PS00099 NA 420 433 IPR020610 Thiolase, active site
Subcellular Localization
Localization 1 Localization mitochondria Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization peroxisome Evidence SUBAcon Pubmed ID 23180787