Basic information
Locus name	AT3G22740
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling
Effect for Senescence	unclear
Gene Description	homocysteine S-methyltransferase 3 (HMT-3) identical to homocysteine S-methyltransferase HMT-3 [Arabidopsis thaliana] GI:9966515; similar to homocysteine S-methyltransferase AtHMT-2 (GI:6685163) [Arabidopsis thaliana]; similar to selenocysteine methyltransferase GB:P56707 from [Astragalus bisulcatus]
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	molecular function homocysteine S-methyltransferase activity
Sequence	AT3G22740.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
Ortholog Group
Ortholog Groups: OG5_128779	Accession Taxon NP_189219 Arabidopsis thaliana NP_191884 Arabidopsis thaliana NP_566715 ( AT3G22740 ) Arabidopsis thaliana NP_974361 Arabidopsis thaliana NP_974482 Arabidopsis thaliana CMO308C Cyanidioschyzon merolae strain 10D NP_001044396 Oryza sativa Japonica Group NP_001049411 Oryza sativa Japonica Group NP_001064628 Oryza sativa Japonica Group NP_001067232 Oryza sativa Japonica Group e_gw1.73.94.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_100044 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_8000022 Physcomitrella patens subsp. patens 27524.m000295 Ricinus communis 29703.m001481 Ricinus communis 29844.m003244 Ricinus communis XP_002951545 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR21091 1.2E-259 7 336 No hit NA ProSiteProfiles PS50970 48.4 12 333 IPR003726 Homocysteine S-methyltransferase SUPERFAMILY SSF82282 9.8E-86 21 337 IPR003726 Homocysteine S-methyltransferase Pfam PF02574 3.5E-88 24 334 IPR003726 Homocysteine S-methyltransferase
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787