Basic information
Locus name	AT5G38710
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling
Effect for Senescence	unclear
Gene Description	proline oxidase, putative / osmotic stress-responsive proline dehydrogenase, putative similar to proline oxidase, mitochondrial precursor (Osmotic stress- induced proline dehydrogenase) [Arabidopsis thaliana] SWISS-PROT:P92983
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process glutamate biosynthetic process oxidation-reduction process proline catabolic process molecular function proline dehydrogenase activity
Pathway	KEGG map00330 (EC 1.5.99.8) MetaCyc PWY-5737
Sequence	AT5G38710.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT5G38710.1  miRNA: ath-miR837-5p miRNA: ath-miR837-5p mfe: -21.7 kcal/mol  p-value: 0.109882  position:  790  target 5' A              C    A 3'             GGAA GAACGAGAG UUGA              CUUU CUUGUUCUU GACU   miRNA  3' A    G         U    A 5'
Ortholog Group
Ortholog Groups: OG5_127738	Accession Taxon NP_189701 Arabidopsis thaliana NP_198687 ( AT5G38710 ) Arabidopsis thaliana CMG213C Cyanidioschyzon merolae strain 10D 146649 Chlamydomonas reinhardtii 193221 Chlamydomonas reinhardtii NP_001065321 Oryza sativa Japonica Group 0400010309 Ostreococcus tauri e_gw1.242.58.1 Physcomitrella patens subsp. patens e_gw1.26.206.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_640085 Physcomitrella patens subsp. patens 30167.m000877 Ricinus communis e_gw1.2.110.1 Thalassiosira pseudonana CCMP1335 XP_002952289 Volvox carteri f. nagariensis XP_002953915 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR13914 3.3E-156 1 475 IPR015659 Proline oxidase SUPERFAMILY SSF51730 3.1E-75 113 187 No hit NA Pfam PF01619 2.5E-97 119 464 IPR002872 Proline dehydrogenase SUPERFAMILY SSF51730 3.1E-75 233 475 No hit NA
Subcellular Localization
Localization	mitochondrion
Evidence	SUBAcon
Pubmed ID	23180787