Basic information
Locus name	AT1G66200
Alias	GLN1-2/GSR2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification:glutamate synthetase
Effect for Senescence	unclear
Gene Description	encodes a cytosolic glutamate synthetase
Evidence	Proteomic evidence [Ref 1]
References	1: Bindschedler LV, Palmblad M, Cramer R Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study. Phytochemistry 2008 Jul;69(10):1962-72
Gene Ontology	biological process glutamine biosynthetic process nitrogen compound metabolic process molecular function glutamate-ammonia ligase activity
Pathway	KEGG map00250 (EC 6.3.1.2) map00330 (EC 6.3.1.2) map00910 (EC 6.3.1.2) MetaCyc PWY-3282
Sequence	AT1G66200.1 | Genomic | mRNA | CDS | Protein AT1G66200.2 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT1G66200.1  miRNA: ath-miR837-5p miRNA: ath-miR837-5p mfe: -22.1 kcal/mol  p-value: 0.079432  position:  918  target 5' A   G    U         U  C 3'             GAA GCGA CGAGAAGCU GG              CUU UGCU GUUCUUUGA CU   miRNA  3' A        U            A 5'  target: AT1G66200.1  miRNA: ath-miR843 miRNA: ath-miR843 mfe: -27.6 kcal/mol  p-value: 0.012527  position:  926  target 5' A                    A 3'             UCGA GAAGCUUGGCUUGAG              GGUU CUUCGAGCUGGAUUU   miRNA  3' A    A                 5'  target: AT1G66200.1  miRNA: ath-miR851-5p miRNA: ath-miR851-5p mfe: -28.5 kcal/mol  p-value: 0.008807  position:  1032  target 5' U   G  U           U  U 3'             UUG GG GUUGCGAACCG GG              AAC CC UAGCGCUUGGC CU   miRNA  3' G   A              U    5'
Ortholog Group
Ortholog Groups: OG5_127569	Accession Taxon NP_001031969 Arabidopsis thaliana NP_001078639 Arabidopsis thaliana NP_175280 Arabidopsis thaliana NP_176794 ( AT1G66200 ) Arabidopsis thaliana NP_188409 Arabidopsis thaliana NP_198413 Arabidopsis thaliana NP_198576 Arabidopsis thaliana NP_568335 Arabidopsis thaliana CMI233C Cyanidioschyzon merolae strain 10D 129468 Chlamydomonas reinhardtii 133971 Chlamydomonas reinhardtii 136895 Chlamydomonas reinhardtii ACO63243 Micromonas sp. RCC299 NP_001048045 Oryza sativa Japonica Group NP_001049424 Oryza sativa Japonica Group NP_001051067 Oryza sativa Japonica Group NP_001054133 Oryza sativa Japonica Group e_gw1.241.101.1 Physcomitrella patens subsp. patens e_gw1.40.194.1 Physcomitrella patens subsp. patens estExt_fgenesh1_kg.C_190003 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_190154 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_3450002 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_3450001 Physcomitrella patens subsp. patens 29675.m000392 Ricinus communis 29726.m003921 Ricinus communis estExt_fgenesh1_kg.C_chr_220004 Thalassiosira pseudonana CCMP1335 XP_002947417 Volvox carteri f. nagariensis XP_002947554 Volvox carteri f. nagariensis XP_002956198 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR20852 5.0E-123 9 252 No hit NA SUPERFAMILY SSF54368 5.9E-18 13 102 IPR008147 Glutamine synthetase, beta-Grasp Pfam PF03951 6.7E-19 20 97 IPR008147 Glutamine synthetase, beta-Grasp ProSitePatterns PS00180 NA 55 72 IPR027302 Glutamine synthetase, N-terminal conserved site Pfam PF00120 1.8E-35 104 252 IPR008146 Glutamine synthetase, catalytic domain SUPERFAMILY SSF55931 3.1E-42 104 252 No hit NA
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787