Basic information
Locus name	AT1G28580
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Lipid/Carbohydrate metabolism
Effect for Senescence	unclear
Gene Description	GDSL-motif lipase, putative similar to lipase [Arabidopsis thaliana] GI:1145627; contains InterPro Entry IPR001087 Lipolytic enzyme, G-D-S-L family
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85 2: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process lipid metabolic process molecular function hydrolase activity, acting on ester bonds
Sequence	AT1G28580.1 | Genomic | mRNA | CDS | Protein AT1G28580.2 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT1G28580.1  miRNA: ath-miR837-5p miRNA: ath-miR837-5p mfe: -25.8 kcal/mol  p-value: 0.013697  position:  641  target 5' U     A  U            G 3'             UGAAG GA CAAGGAGCUGAU              ACUUU CU GUUCUUUGACUA   miRNA  3'       G  U              5'  target: AT1G28580.2  miRNA: ath-miR837-5p miRNA: ath-miR837-5p mfe: -25.8 kcal/mol  p-value: 0.016395  position:  888  target 5' U     A  U            G 3'             UGAAG GA CAAGGAGCUGAU              ACUUU CU GUUCUUUGACUA   miRNA  3'       G  U              5'
Ortholog Group
Ortholog Groups: OG5_136635	Accession Taxon NP_001031103 Arabidopsis thaliana NP_001031122 Arabidopsis thaliana NP_174179 Arabidopsis thaliana NP_174180 ( AT1G28580 ) Arabidopsis thaliana NP_174181 Arabidopsis thaliana NP_174182 Arabidopsis thaliana NP_174185 Arabidopsis thaliana NP_174186 Arabidopsis thaliana NP_174188 Arabidopsis thaliana NP_174440 Arabidopsis thaliana NP_180304 Arabidopsis thaliana NP_564313 Arabidopsis thaliana NP_564314 Arabidopsis thaliana NP_849723 Arabidopsis thaliana NP_973930 Arabidopsis thaliana NP_973931 Arabidopsis thaliana NP_973932 Arabidopsis thaliana NP_001043560 Oryza sativa Japonica Group NP_001043721 Oryza sativa Japonica Group NP_001043722 Oryza sativa Japonica Group NP_001043724 Oryza sativa Japonica Group
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR22835 6.6E-93 8 279 No hit NA Pfam PF00657 1.5E-17 33 281 IPR001087 Lipase, GDSL SUPERFAMILY SSF52266 4.5E-8 33 43 No hit NA SUPERFAMILY SSF52266 4.5E-8 81 220 No hit NA SUPERFAMILY SSF52266 4.5E-8 254 283 No hit NA
Subcellular Localization
Localization	extracellular
Evidence	SUBAcon
Pubmed ID	23180787