Basic information
Locus name	AT5G48880
Alias	KAT5/PKT1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Hormone response pathway:JA biosynthesis
Effect for Senescence	promote
Gene Description	Encodes a peroxisomal 3-keto-acyl-CoA thiolase 5 precursor.Probably involved in long chain fatty-acid beta-oxidation prior to gluconeogenesis during germination and subsequent seedling growth. Involved in systemic jasmonic acid (JA) biosynthesis after wounding and may be during senescence.
Evidence	Molecular evidence:Northern [Ref 1]
References	1: He Y, Fukushige H, Hildebrand DF, Gan S Evidence supporting a role of jasmonic acid in Arabidopsis leaf senescence. Plant Physiol. 2002 Mar;128(3):876-84
Gene Ontology	biological process metabolic process molecular function transferase activity, transferring acyl groups other than amino-acyl groups
Pathway	Reactome REACT_22258
Sequence	AT5G48880.1 | Genomic | mRNA | CDS | Protein AT5G48880.2 | Genomic | mRNA | CDS | Protein AT5G48880.3 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT5G48880.1  miRNA: ath-miR834 miRNA: ath-miR834 mfe: -27.3 kcal/mol  p-value: 0.015184  position:  456  target 5' G      A          U   U 3'             UUGCUG UGUUGCUGCU CCA              AAUGGU GCGAUGACGA GGU   miRNA  3'        G          U     5'  target: AT5G48880.2  miRNA: ath-miR834 miRNA: ath-miR834 mfe: -27.3 kcal/mol  p-value: 0.016939  position:  613  target 5' G      A          U   U 3'             UUGCUG UGUUGCUGCU CCA              AAUGGU GCGAUGACGA GGU   miRNA  3'        G          U     5'  target: AT5G48880.3  miRNA: ath-miR834 miRNA: ath-miR834 mfe: -27.3 kcal/mol  p-value: 0.015564  position:  497  target 5' G      A          U   U 3'             UUGCUG UGUUGCUGCU CCA              AAUGGU GCGAUGACGA GGU   miRNA  3'        G          U     5'
Ortholog Group
Ortholog Groups: OG5_128333	Accession Taxon NP_001032037 ( AT5G48880 ) Arabidopsis thaliana NP_171965 Arabidopsis thaliana NP_180873 Arabidopsis thaliana NP_568704 Arabidopsis thaliana NP_851157 Arabidopsis thaliana 138637 Chlamydomonas reinhardtii ACO61553 Micromonas sp. RCC299 NP_001048523 Oryza sativa Japonica Group NP_001064764 Oryza sativa Japonica Group e_gw1.06.00.191.1 Ostreococcus tauri e_gw1.55.167.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_670017 Physcomitrella patens subsp. patens 29904.m002984 Ricinus communis 30204.m001789 Ricinus communis e_gw1.11a.55.1 Thalassiosira pseudonana CCMP1335 XP_002946078 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR18919 7.1E-260 1 398 IPR002155 Thiolase SUPERFAMILY SSF53901 8.8E-67 4 267 IPR016039 Thiolase-like PIRSF PIRSF000429 8.4E-156 5 398 IPR002155 Thiolase Pfam PF00108 1.2E-77 6 265 IPR020616 Thiolase, N-terminal TIGRFAM TIGR01930 1.3E-132 10 395 IPR002155 Thiolase ProSitePatterns PS00098 NA 90 108 IPR020615 Thiolase, acyl-enzyme intermediate active site Pfam PF02803 3.1E-48 273 396 IPR020617 Thiolase, C-terminal SUPERFAMILY SSF53901 3.4E-41 275 396 IPR016039 Thiolase-like ProSitePatterns PS00737 NA 341 357 IPR020613 Thiolase, conserved site ProSitePatterns PS00099 NA 378 391 IPR020610 Thiolase, active site
Subcellular Localization
Localization	peroxisome
Evidence	SUBAcon
Pubmed ID	23180787