Basic information
Locus name	AT5G50210
Alias	OLD5/QS/SUFE3
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation:ROS
Effect for Senescence	delay
Gene Description	Encodes an Fe-S binding protein with quinolinate synthase (QS) activity and cysteine desulfurase activator activity, localized in the chloroplast.
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Schippers JH, Nunes-Nesi A, Apetrei R, Hille J, Fernie AR, Dijkwel PP The Arabidopsis onset of leaf death5 mutation of quinolinate synthase affects nicotinamide adenine dinucleotide biosynthesis and causes early ageing. Plant Cell 2008 Oct;20(10):2909-25
Gene Ontology	biological process NAD biosynthetic process molecular function quinolinate synthetase A activity
Pathway
Sequence	AT5G50210.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutant name	old5
Mutant/Transgenic	mutant
Ecotype	Ler
Mutagenesis type	EMS
miRNA Interaction
Details	target: AT5G50210.1  miRNA: ath-miR396a miRNA: ath-miR396a mfe: -28.5 kcal/mol  p-value: 0.005252  position:  1790  target 5' A             A     C 3'             GGUUC AGGAAGC GUGGA              UCAAG UCUUUCG CACCU   miRNA  3' G     U       A     U 5'  target: AT5G50210.1  miRNA: ath-miR396b miRNA: ath-miR396b mfe: -28.4 kcal/mol  p-value: 0.006751  position:  1789  target 5' A              A     C 3'             AGGUUC AGGAAGC GUGGA              UUCAAG UCUUUCG CACCU   miRNA  3'        U       A     U 5'
Ortholog Group
Ortholog Groups: OG5_144453	Accession Taxon NP_199832 ( AT5G50210 ) Arabidopsis thaliana 112673 Chlamydomonas reinhardtii ACO63561 Micromonas sp. RCC299 NP_001066600 Oryza sativa Japonica Group fgenesh1_pm.C_Chr_17.0001000025 Ostreococcus tauri e_gw1.20.29.1 Physcomitrella patens subsp. patens e_gw1.71.25.1 Physcomitrella patens subsp. patens 30147.m013851 Ricinus communis 30147.m013852 Ricinus communis thaps1_ua_kg.chr_4000001 Thalassiosira pseudonana CCMP1335 XP_002955035 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description SUPERFAMILY SSF82649 2.4E-29 85 222 No hit NA Pfam PF02657 8.5E-18 91 214 IPR003808 Fe-S metabolism associated domain, SufE-like PANTHER PTHR30573 8.9E-24 236 572 No hit NA SUPERFAMILY SSF142754 3.3E-53 262 576 No hit NA Pfam PF02445 1.0E-29 265 574 IPR003473 Quinolinate synthetase A SUPERFAMILY SSF142754 3.3E-53 627 659 No hit NA
Subcellular Localization
Localization	plastid
Evidence	SUBAcon
Pubmed ID	23180787