Basic information
Locus name	AT4G10380
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling
Effect for Senescence	unclear
Gene Description	major intrinsic family protein / MIP family protein contains Pfam profile: MIP PF00230
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process transport cellular component membrane molecular function transporter activity
Sequence	AT4G10380.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT4G10380.1  miRNA: ath-miR5021 miRNA: ath-miR5021 mfe: -27.7 kcal/mol  p-value: 0.000222  position: 24  target 5' A     G              A  3'             UUUUC UUUUCUUCUUCUCA                 AAAAG AGAAGAAGAAGAGU      miRNA  3'       A                 5'
Ortholog Group
Ortholog Groups: OG5_177931	Accession Taxon NP_192776 ( AT4G10380 ) Arabidopsis thaliana NP_001065048 Oryza sativa Japonica Group e_gw1.258.27.1 Physcomitrella patens subsp. patens 30068.m002640 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR19139 3.8E-136 33 304 IPR000425 Major intrinsic protein Pfam PF00230 2.6E-50 74 283 IPR000425 Major intrinsic protein SUPERFAMILY SSF81338 7.6E-61 75 288 IPR023271 Aquaporin-like PRINTS PR00783 1.0E-38 78 97 IPR000425 Major intrinsic protein PRINTS PR00783 1.0E-38 117 141 IPR000425 Major intrinsic protein ProSitePatterns PS00221 NA 135 143 IPR022357 Major intrinsic protein, conserved site PRINTS PR00783 1.0E-38 154 173 IPR000425 Major intrinsic protein PRINTS PR00783 1.0E-38 198 216 IPR000425 Major intrinsic protein PRINTS PR00783 1.0E-38 229 251 IPR000425 Major intrinsic protein PRINTS PR00783 1.0E-38 266 286 IPR000425 Major intrinsic protein
Subcellular Localization
Localization	plasma membrane
Evidence	SUBAcon
Pubmed ID	23180787