Basic information
Locus name	AT4G21120
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling
Effect for Senescence	unclear
Gene Description	amino acid permease family protein similar to cationic amino acid transporter-1 [Rattus norvegicus] GI:1589917; contains Pfam profile PF00324: Amino acid permease
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process amino acid transmembrane transport cellular component membrane molecular function amino acid transmembrane transporter activity
Sequence	AT4G21120.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT4G21120.1  miRNA: ath-miR157a miRNA: ath-miR157a mfe: -30.2 kcal/mol  p-value: 0.001555  position:  631  target 5' A       C           C 3'             UGCUCUC GUCUUUUGUUA              ACGAGAG UAGAAGACAGU   miRNA  3' C       A           U 5'  target: AT4G21120.1  miRNA: ath-miR157b miRNA: ath-miR157b mfe: -30.2 kcal/mol  p-value: 0.001349  position:  631  target 5' A       C           C 3'             UGCUCUC GUCUUUUGUUA              ACGAGAG UAGAAGACAGU   miRNA  3' C       A           U 5'  target: AT4G21120.1  miRNA: ath-miR157c miRNA: ath-miR157c mfe: -30.2 kcal/mol  p-value: 0.000796  position:  631  target 5' A       C           C 3'             UGCUCUC GUCUUUUGUUA              ACGAGAG UAGAAGACAGU   miRNA  3' C       A           U 5'  target: AT4G21120.1  miRNA: ath-miR417 miRNA: ath-miR417 mfe: -24.1 kcal/mol  p-value: 0.020920  position:  712  target 5' C        C     G      A 3'             UCG GCGA UUCAU GCCUUC              AGC UGUU AAGUG UGGAAG   miRNA  3'     U    U     A        5'  target: AT4G21120.1  miRNA: ath-miR822 miRNA: ath-miR822 mfe: -27.2 kcal/mol  p-value: 0.013241  position:  1475  target 5' C               G     A 3'             CGUG GU AAUGCUU CCGCG              GUAC CG UUACGAA GGCGU   miRNA  3'      A  U       G       5'
Ortholog Group
Ortholog Groups: OG5_141558	Accession Taxon NP_173155 Arabidopsis thaliana NP_181041 Arabidopsis thaliana NP_193844 ( AT4G21120 ) Arabidopsis thaliana NP_001042365 Oryza sativa Japonica Group NP_001050746 Oryza sativa Japonica Group NP_001057802 Oryza sativa Japonica Group estExt_fgenesh1_pg.C_490099 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_90186 Physcomitrella patens subsp. patens 29801.m003214 Ricinus communis 29932.m000608 Ricinus communis 29932.m000609 Ricinus communis 30075.m001193 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11785 5.1E-225 23 582 IPR002293 Amino acid/polyamine transporter I Pfam PF13520 2.7E-50 74 476 No hit NA Pfam PF13906 2.7E-16 513 562 No hit NA
Subcellular Localization
Localization	plasma membrane
Evidence	SUBAcon
Pubmed ID	23180787