Basic information
Locus name	AT5G04900
Alias	NOL
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Chlorophyll degradation:Degradation of chlorophyll b and LHCII
Effect for Senescence	promote
Gene Description	Encodes a chlorophyll b reducatase involved in the degradation of chlorophyll b and LHCII (light harvesting complex II).
Evidence	Genetic evidence: mutant [Ref 1]; Proteomic evidence [Ref 2]
References	1: Zybailov B, Rutschow H, Friso G, Rudella A, Emanuelsson O, Sun Q, van Wijk KJ Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. PLoS ONE 2008;3(4):e1994 2: Horie Y, Ito H, Kusaba M, Tanaka R, Tanaka A Participation of chlorophyll b reductase in the initial step of the degradation of light-harvesting chlorophyll a/b-protein complexes in Arabidopsis. J. Biol. Chem. 2009 Jun 26;284(26):17449-56
Gene Ontology	biological process metabolic process molecular function oxidoreductase activity
Sequence	AT5G04900.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutant name	35S-NOL-GFP
Mutant/Transgenic	transgenic
Ecotype	Col-0
Mutagenesis type	transgene
miRNA Interaction
Details	target: AT5G04900.1  miRNA: ath-miR5014a-5p miRNA: ath-miR5014a-5p mfe: -26.1 kcal/mol  p-value: 0.001008  position: 440  target 5' C        G            G  3'             AUG UGUG GGAACUAAGUGU                 UAC ACAU UUUUGAUUCACA      miRNA  3'     A    G               5'
Ortholog Group
Ortholog Groups: OG5_136329	Accession Taxon NP_567400 Arabidopsis thaliana NP_568145 ( AT5G04900 ) Arabidopsis thaliana CMP155C Cyanidioschyzon merolae strain 10D 194485 Chlamydomonas reinhardtii 205572 Chlamydomonas reinhardtii ACO66601 Micromonas sp. RCC299 ACO70117 Micromonas sp. RCC299 NP_001042468 Oryza sativa Japonica Group NP_001050798 Oryza sativa Japonica Group 1100010225 Ostreococcus tauri gw1.01.00.423.1 Ostreococcus tauri e_gw1.373.14.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_1990001 Physcomitrella patens subsp. patens gw1.100.151.1 Physcomitrella patens subsp. patens 29852.m002016 Ricinus communis 29912.m005516 Ricinus communis fgenesh1_pg.C_chr_9000231 Thalassiosira pseudonana CCMP1335 XP_002948073 Volvox carteri f. nagariensis XP_002956541 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24314 1.7E-189 4 347 No hit NA PRINTS PR00081 5.9E-20 81 98 IPR002347 Glucose/ribitol dehydrogenase SUPERFAMILY SSF51735 2.1E-47 81 299 No hit NA Pfam PF00106 2.2E-26 82 251 IPR002198 Short-chain dehydrogenase/reductase SDR PRINTS PR00080 2.0E-6 156 167 IPR002198 Short-chain dehydrogenase/reductase SDR PRINTS PR00081 5.9E-20 156 167 IPR002347 Glucose/ribitol dehydrogenase PRINTS PR00081 5.9E-20 206 222 IPR002347 Glucose/ribitol dehydrogenase PRINTS PR00080 2.0E-6 212 220 IPR002198 Short-chain dehydrogenase/reductase SDR ProSitePatterns PS00061 NA 220 248 IPR020904 Short-chain dehydrogenase/reductase, conserved site PRINTS PR00080 2.0E-6 233 252 IPR002198 Short-chain dehydrogenase/reductase SDR PRINTS PR00081 5.9E-20 233 252 IPR002347 Glucose/ribitol dehydrogenase PRINTS PR00081 5.9E-20 257 274 IPR002347 Glucose/ribitol dehydrogenase
Subcellular Localization
Localization	plastid
Evidence	SUBAcon
Pubmed ID	23180787