Basic information
Locus name	AT5G52450
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling
Effect for Senescence	unclear
Gene Description	MATE efflux protein-related strong similarity to unknown protein (pir||T02324); contains Pfam profile PF01554 Uncharacterized membrane protein family
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process drug transmembrane transport transmembrane transport cellular component membrane molecular function antiporter activity drug transmembrane transporter activity
Pathway	Reactome REACT_15518 REACT_20633
Sequence	AT5G52450.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT5G52450.1  miRNA: ath-miR835-5p miRNA: ath-miR835-5p mfe: -23.2 kcal/mol  p-value: 0.011212  position:  1162  target 5' U                    U 3'             GAUAAGGAAUAUAUG GGGA              CUAUUUCUUGUAUAC UUCU   miRNA  3'                 G    U 5'
Ortholog Group
Ortholog Groups: OG5_126647	Accession Taxon NP_177332 Arabidopsis thaliana NP_177511 Arabidopsis thaliana NP_180983 Arabidopsis thaliana NP_194643 Arabidopsis thaliana NP_197471 Arabidopsis thaliana NP_199724 Arabidopsis thaliana NP_200058 ( AT5G52450 ) Arabidopsis thaliana CMI258C Cyanidioschyzon merolae strain 10D 114894 Chlamydomonas reinhardtii 135238 Chlamydomonas reinhardtii 189706 Chlamydomonas reinhardtii 193918 Chlamydomonas reinhardtii ACO61130 Micromonas sp. RCC299 ACO62424 Micromonas sp. RCC299 ACO63435 Micromonas sp. RCC299 ACO65386 Micromonas sp. RCC299 ACO66662 Micromonas sp. RCC299 ACO66822 Micromonas sp. RCC299 NP_001051841 Oryza sativa Japonica Group NP_001052573 Oryza sativa Japonica Group NP_001057687 Oryza sativa Japonica Group NP_001057690 Oryza sativa Japonica Group NP_001058524 Oryza sativa Japonica Group NP_001064392 Oryza sativa Japonica Group NP_001064393 Oryza sativa Japonica Group NP_001064394 Oryza sativa Japonica Group 1200010019 Ostreococcus tauri 1700010022 Ostreococcus tauri 1800010157 Ostreococcus tauri e_gw1.13.100.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_1200100 Physcomitrella patens subsp. patens estExt_Genewise1.C_280003 Physcomitrella patens subsp. patens estExt_fgenesh1_kg.C_1830003 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_340358 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_680102 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_145000070 Physcomitrella patens subsp. patens fgenesh1_pm.scaffold_218000015 Physcomitrella patens subsp. patens fgenesh1_pm.scaffold_48000006 Physcomitrella patens subsp. patens gw1.113.35.1 Physcomitrella patens subsp. patens 28565.m000335 Ricinus communis 29726.m004072 Ricinus communis 29908.m006104 Ricinus communis 29912.m005439 Ricinus communis 30115.m001190 Ricinus communis 30147.m013871 Ricinus communis 30147.m013872 Ricinus communis 30179.m000554 Ricinus communis e_gw1.15.40.1 Thalassiosira pseudonana CCMP1335 fgenesh1_pg.C_chr_1000217 Thalassiosira pseudonana CCMP1335 XP_002945697 Volvox carteri f. nagariensis XP_002949590 Volvox carteri f. nagariensis XP_002956473 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11206 9.6E-253 1 477 No hit NA Pfam PF01554 1.4E-34 36 196 IPR002528 Multi antimicrobial extrusion protein TIGRFAM TIGR00797 6.0E-104 36 433 IPR002528 Multi antimicrobial extrusion protein Pfam PF01554 2.7E-33 257 419 IPR002528 Multi antimicrobial extrusion protein
Subcellular Localization
Localization	plasma membrane
Evidence	SUBAcon
Pubmed ID	23180787