Basic information
Locus name	AT3G18830
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling
Effect for Senescence	unclear
Gene Description	mannitol transporter, putative similar to mannitol transporter [Apium graveolens var. dulce] GI:12004316; contains Pfam profile PF00083: major facilitator superfamily protein
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process transmembrane transport cellular component membrane molecular function substrate-specific transmembrane transporter activity
Pathway	Reactome REACT_15518
Sequence	AT3G18830.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT3G18830.1  miRNA: ath-miR394a miRNA: ath-miR394a mfe: -27.3 kcal/mol  p-value: 0.018989  position:  1377  target 5' U  U    A        A    U 3'             GG GGUG ACAGAGUG CUAG              CC CCAC UGUCUUAC GGUU   miRNA  3'    U    C               5'  target: AT3G18830.1  miRNA: ath-miR394b miRNA: ath-miR394b mfe: -27.3 kcal/mol  p-value: 0.015300  position:  1377  target 5' U  U    A        A    U 3'             GG GGUG ACAGAGUG CUAG              CC CCAC UGUCUUAC GGUU   miRNA  3'    U    C               5'
Ortholog Group
Ortholog Groups: OG5_134003	Accession Taxon NP_179209 Arabidopsis thaliana NP_179210 Arabidopsis thaliana NP_188513 ( AT3G18830 ) Arabidopsis thaliana NP_001045505 Oryza sativa Japonica Group NP_001060108 Oryza sativa Japonica Group NP_001060109 Oryza sativa Japonica Group NP_001066878 Oryza sativa Japonica Group NP_001068332 Oryza sativa Japonica Group NP_001068334 Oryza sativa Japonica Group 29851.m002435 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24063 0.0 6 535 No hit NA TIGRFAM TIGR00879 9.3E-104 22 493 IPR003663 Sugar/inositol transporter SUPERFAMILY SSF103473 2.0E-68 27 242 IPR016196 Major facilitator superfamily domain, general substrate transporter Pfam PF00083 2.4E-107 39 498 IPR005828 General substrate transporter ProSiteProfiles PS50850 48.0 39 487 IPR020846 Major facilitator superfamily domain PRINTS PR00171 6.8E-23 47 57 IPR003663 Sugar/inositol transporter ProSitePatterns PS00216 NA 93 110 IPR005829 Sugar transporter, conserved site PRINTS PR00171 6.8E-23 130 149 IPR003663 Sugar/inositol transporter ProSitePatterns PS00217 NA 135 160 IPR005829 Sugar transporter, conserved site SUPERFAMILY SSF103473 2.0E-68 277 496 IPR016196 Major facilitator superfamily domain, general substrate transporter PRINTS PR00171 6.8E-23 305 315 IPR003663 Sugar/inositol transporter PRINTS PR00171 6.8E-23 399 420 IPR003663 Sugar/inositol transporter PRINTS PR00171 6.8E-23 422 434 IPR003663 Sugar/inositol transporter
Subcellular Localization
Localization 1 Localization plasma membrane Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization plasma membrane Evidence SUBAcon Pubmed ID 23180787