Basic information
Locus name	AT4G29130
Alias	HXK1/GIN2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others:Glucose
Effect for Senescence	promote
Gene Description	Encodes a hexokinase (HXK1) in the plant glucose-signaling network. Functions as a glucose sensor to interrelate nutrient.
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Moore B, Zhou L, Rolland F, Hall Q, Cheng WH, Liu YX, Hwang I, Jones T, Sheen J Role of the Arabidopsis glucose sensor HXK1 in nutrient, light, and hormonal signaling. Science 2003 Apr 11;300(5617):332-6
Gene Ontology	biological process carbohydrate metabolic process molecular function ATP binding phosphotransferase activity, alcohol group as acceptor
Pathway	KEGG map00010 (EC 2.7.1.1) map00051 (EC 2.7.1.1) map00052 (EC 2.7.1.1) map00500 (EC 2.7.1.1) map00520 (EC 2.7.1.1) map00521 (EC 2.7.1.1) map00524 (EC 2.7.1.1) MetaCyc PWY-621 PWY-6531
Sequence	AT4G29130.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutant name	gin2-1
Mutant/Transgenic	mutant
Ecotype	Ler
Mutagenesis type	EMS
Ortholog Group
Ortholog Groups: OG5_126743	Accession Taxon NP_001077921 Arabidopsis thaliana NP_175220 Arabidopsis thaliana NP_179576 Arabidopsis thaliana NP_194642 ( AT4G29130 ) Arabidopsis thaliana 21582 Chlamydomonas reinhardtii NP_001042264 Oryza sativa Japonica Group NP_001044214 Oryza sativa Japonica Group NP_001045354 Oryza sativa Japonica Group NP_001056082 Oryza sativa Japonica Group NP_001059124 Oryza sativa Japonica Group NP_001059538 Oryza sativa Japonica Group e_gw1.12.202.1 Physcomitrella patens subsp. patens e_gw1.3.308.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_4010007 Physcomitrella patens subsp. patens estExt_Genewise1.C_4140012 Physcomitrella patens subsp. patens estExt_Genewise1.C_450097 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_1500009 Physcomitrella patens subsp. patens fgenesh1_pm.scaffold_58000019 Physcomitrella patens subsp. patens fgenesh1_pm.scaffold_84000041 Physcomitrella patens subsp. patens 29912.m005437 Ricinus communis 30146.m003501 Ricinus communis 30170.m014176 Ricinus communis XP_002956604 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description SUPERFAMILY SSF53067 2.7E-71 23 242 No hit NA PANTHER PTHR19443 7.7E-248 36 494 IPR001312 Hexokinase Pfam PF00349 5.0E-57 42 240 IPR022672 Hexokinase, N-terminal PRINTS PR00475 1.4E-64 98 114 IPR001312 Hexokinase PRINTS PR00475 1.4E-64 172 197 IPR001312 Hexokinase ProSitePatterns PS00378 NA 172 197 IPR019807 Hexokinase, conserved site PRINTS PR00475 1.4E-64 224 240 IPR001312 Hexokinase SUPERFAMILY SSF53067 5.1E-80 244 490 No hit NA PRINTS PR00475 1.4E-64 247 261 IPR001312 Hexokinase Pfam PF03727 1.0E-66 249 487 IPR022673 Hexokinase, C-terminal PRINTS PR00475 1.4E-64 312 334 IPR001312 Hexokinase PRINTS PR00475 1.4E-64 395 417 IPR001312 Hexokinase PRINTS PR00475 1.4E-64 472 488 IPR001312 Hexokinase
Subcellular Localization
Localization 1 Localization mitochondria Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization mitochondrion Evidence SUBAcon Pubmed ID 23180787