Basic information
Locus name	AT5G10140
Alias	FLC
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Signal transduction:Flowering
Effect for Senescence	delay
Gene Description	Mutant in FLC has a premature senescence phenotype
Evidence	Genetic evidence:QTL [Ref 1]
References	1: Wingler A, Purdy SJ, Edwards SA, Chardon F, Masclaux-Daubresse C QTL analysis for sugar-regulated leaf senescence supports flowering-dependent and -independent senescence pathways. New Phytol. 2010 Jan;185(2):420-33
Gene Ontology	molecular function DNA binding protein dimerization activity
Pathway	Reactome REACT_21303
Sequence	AT5G10140.1 | Genomic | mRNA | CDS | Protein AT5G10140.2 | Genomic | mRNA | CDS | Protein AT5G10140.3 | Genomic | mRNA | CDS | Protein AT5G10140.4 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_139532	Accession Taxon NP_001032144 Arabidopsis thaliana NP_001078563 Arabidopsis thaliana NP_001078798 Arabidopsis thaliana NP_001078799 Arabidopsis thaliana NP_001119498 Arabidopsis thaliana NP_001119499 Arabidopsis thaliana NP_001154703 Arabidopsis thaliana NP_177833 Arabidopsis thaliana NP_196576 ( AT5G10140 ) Arabidopsis thaliana NP_201311 Arabidopsis thaliana NP_201312 Arabidopsis thaliana NP_201313 Arabidopsis thaliana NP_569005 Arabidopsis thaliana NP_850979 Arabidopsis thaliana NP_850980 Arabidopsis thaliana NP_974160 Arabidopsis thaliana
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11945 2.5E-134 1 178 No hit NA ProSiteProfiles PS50066 30.0 1 61 IPR002100 Transcription factor, MADS-box SMART SM00432 7.9E-35 1 60 IPR002100 Transcription factor, MADS-box SUPERFAMILY SSF55455 2.4E-28 2 79 IPR002100 Transcription factor, MADS-box PRINTS PR00404 6.9E-26 3 23 IPR002100 Transcription factor, MADS-box ProSitePatterns PS00350 NA 3 57 IPR002100 Transcription factor, MADS-box Pfam PF00319 4.8E-22 9 59 IPR002100 Transcription factor, MADS-box PRINTS PR00404 6.9E-26 23 38 IPR002100 Transcription factor, MADS-box PRINTS PR00404 6.9E-26 38 59 IPR002100 Transcription factor, MADS-box ProSiteProfiles PS51297 11.8 80 170 IPR002487 Transcription factor, K-box Pfam PF01486 7.2E-13 84 165 IPR002487 Transcription factor, K-box Coils Coil NA 139 167 No hit NA
Subcellular Localization
Localization	nucleus
Evidence	SUBAcon
Pubmed ID	23180787