Basic information
Locus name	AT1G06430
Alias	FtsH8
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Chlorophyll degradation
Effect for Senescence	unclear
Gene Description	encodes a FtsH protease that is localized to the chloroplast protein_coding FTSH PROTEASE 8 (ftsh8)
Evidence	Molecular evidence:Blast search [Ref 1]
References	1: Snowden KC, Simkin AJ, Janssen BJ, Templeton KR, Loucas HM, Simons JL, Karunairetnam S, Gleave AP, Clark DG, Klee HJ The Decreased apical dominance1/Petunia hybrida CAROTENOID CLEAVAGE DIOXYGENASE8 gene affects branch production and plays a role in leaf senescence, root growth, and flower development. Plant Cell 2005 Mar;17(3):746-59
Gene Ontology	biological process protein catabolic process proteolysis cellular component membrane molecular function ATP binding metalloendopeptidase activity zinc ion binding
Sequence	AT1G06430.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_126616	Accession Taxon NP_172231 Arabidopsis thaliana NP_563766 ( AT1G06430 ) Arabidopsis thaliana NP_564563 Arabidopsis thaliana NP_565616 Arabidopsis thaliana NP_568311 Arabidopsis thaliana NP_568604 Arabidopsis thaliana NP_568787 Arabidopsis thaliana NP_850129 Arabidopsis thaliana NP_850156 Arabidopsis thaliana CME055C Cyanidioschyzon merolae strain 10D CMF159C Cyanidioschyzon merolae strain 10D CMI157C Cyanidioschyzon merolae strain 10D CMQ295C Cyanidioschyzon merolae strain 10D CMV129C Cyanidioschyzon merolae strain 10D 116904 Chlamydomonas reinhardtii 55270 Chlamydomonas reinhardtii 58334 Chlamydomonas reinhardtii 61144 Chlamydomonas reinhardtii ACO65058 Micromonas sp. RCC299 ACO66730 Micromonas sp. RCC299 ACO67253 Micromonas sp. RCC299 ACO68844 Micromonas sp. RCC299 ACO69882 Micromonas sp. RCC299 NP_001043384 Oryza sativa Japonica Group NP_001043385 Oryza sativa Japonica Group NP_001044774 Oryza sativa Japonica Group NP_001055745 Oryza sativa Japonica Group NP_001058321 Oryza sativa Japonica Group NP_001058625 Oryza sativa Japonica Group e_gw1.14.00.33.1 Ostreococcus tauri e_gw1.17.00.77.1 Ostreococcus tauri estExt_gwp_GeneWisePlus.C_Chr_09.00010447 Ostreococcus tauri estExt_gwp_GeneWisePlus.C_Chr_10.00010428 Ostreococcus tauri fgenesh1_pm.C_Chr_01.0001000058 Ostreococcus tauri e_gw1.118.126.1 Physcomitrella patens subsp. patens e_gw1.178.57.1 Physcomitrella patens subsp. patens e_gw1.44.44.1 Physcomitrella patens subsp. patens e_gw1.9.269.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_100143 Physcomitrella patens subsp. patens estExt_Genewise1.C_4560008 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_1560021 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_3460014 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_1800036 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_230101 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_390082 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_90173 Physcomitrella patens subsp. patens 28838.m000257 Ricinus communis 29767.m000207 Ricinus communis 29794.m003305 Ricinus communis 29993.m001041 Ricinus communis 30169.m006526 Ricinus communis 30170.m014336 Ricinus communis e_gw1.2.77.1 Thalassiosira pseudonana CCMP1335 e_gw1.32x49.1.1 Thalassiosira pseudonana CCMP1335 e_gw1.6.79.1 Thalassiosira pseudonana CCMP1335 estExt_fgenesh1_pm.C_bd_26x410014 Thalassiosira pseudonana CCMP1335 estExt_gwp_gw1.C_chr_70149 Thalassiosira pseudonana CCMP1335 XP_002948337 Volvox carteri f. nagariensis XP_002949662 Volvox carteri f. nagariensis XP_002952368 Volvox carteri f. nagariensis XP_002956225 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description Hamap MF_01458 35.1 21 670 IPR005936 Peptidase, FtsH PANTHER PTHR23076 0.0 41 672 No hit NA Pfam PF06480 3.6E-7 62 151 IPR011546 Peptidase M41, FtsH extracellular TIGRFAM TIGR01241 2.6E-212 166 659 IPR005936 Peptidase, FtsH SUPERFAMILY SSF52540 2.0E-69 214 459 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMART SM00382 1.8E-24 252 391 IPR003593 AAA+ ATPase domain Pfam PF00004 1.8E-45 256 387 IPR003959 ATPase, AAA-type, core ProSitePatterns PS00674 NA 359 377 IPR003960 ATPase, AAA-type, conserved site Pfam PF01434 1.7E-77 450 658 IPR000642 Peptidase M41 SUPERFAMILY SSF140990 4.8E-64 471 669 No hit NA
Subcellular Localization
Localization	plastid
Evidence	SUBAcon
Pubmed ID	23180787