Basic information
Locus name	AT5G41700
Alias	UBC8
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification:ubiquitin
Effect for Senescence	unclear
Gene Description	Ubiquitin-conjugating enzyme E2. Interaction with NLA. Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins
Evidence	Molecular evidence:Y2H [Ref 1]
References	1: Peng M, Hannam C, Gu H, Bi YM, Rothstein SJ A mutation in NLA, which encodes a RING-type ubiquitin ligase, disrupts the adaptability of Arabidopsis to nitrogen limitation. Plant J. 2007 Apr;50(2):320-37
Gene Ontology	molecular function acid-amino acid ligase activity
Pathway
Sequence	AT5G41700.1 | Genomic | mRNA | CDS | Protein AT5G41700.2 | Genomic | mRNA | CDS | Protein AT5G41700.3 | Genomic | mRNA | CDS | Protein AT5G41700.4 | Genomic | mRNA | CDS | Protein
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24068 1.3E-114 1 147 No hit NA SUPERFAMILY SSF54495 2.6E-66 2 147 IPR016135 Ubiquitin-conjugating enzyme/RWD-like ProSiteProfiles PS50127 48.5 4 136 IPR000608 Ubiquitin-conjugating enzyme, E2 SMART SM00212 4.7E-80 4 147 No hit NA Pfam PF00179 1.4E-52 5 141 IPR000608 Ubiquitin-conjugating enzyme, E2 ProSitePatterns PS00183 NA 74 89 IPR023313 Ubiquitin-conjugating enzyme, active site
Subcellular Localization
Localization	plasma membrane,peroxisome
Evidence	SUBAcon
Pubmed ID	23180787