Basic information
Locus name	AT2G26170
Alias	MAX1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Hormone response pathway:Auxin
Effect for Senescence	unclear
Gene Description	Encodes a protein with similarity to thromboxane-A synthase, member of the CYP711A cytochrome P450 family. MAX1 is a specific repressor of vegetative axillary buds generated by the axillary meristem. Expressed in vascular traces in the rosette stem and axillary buds throughout plant development. Mutants have increased axillary branches. Along with MAX3,4 thought to mediate control of shoot branching via synthesis of a signal molecule which is transported over long distance mediated by MAX2. cDNA supports the existence of the longer transcript predicted for this locus, no cDNA isolated for shorter transcript. MAX1 downregulates 11 genes involved in flavonoid pathway (CHS, CHI, F3H, F3'H, FLS, DFR, ANS, UFGT, RT, AAC and GST).
Evidence	Molecular evidence:Blast search [Ref 1]
References	1: Snowden KC, Simkin AJ, Janssen BJ, Templeton KR, Loucas HM, Simons JL, Karunairetnam S, Gleave AP, Clark DG, Klee HJ The Decreased apical dominance1/Petunia hybrida CAROTENOID CLEAVAGE DIOXYGENASE8 gene affects branch production and plays a role in leaf senescence, root growth, and flower development. Plant Cell 2005 Mar;17(3):746-59
Gene Ontology	biological process oxidation-reduction process molecular function electron carrier activity heme binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Pathway	Reactome REACT_13433
Sequence	AT2G26170.1 | Genomic | mRNA | CDS | Protein AT2G26170.2 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_136840	Accession Taxon NP_565617 ( AT2G26170 ) Arabidopsis thaliana NP_850074 Arabidopsis thaliana NP_001046325 Oryza sativa Japonica Group
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24301 7.9E-68 1 438 No hit NA Pfam PF00067 1.0E-73 1 412 IPR001128 Cytochrome P450 SUPERFAMILY SSF48264 1.7E-88 1 438 IPR001128 Cytochrome P450 PRINTS PR00463 2.5E-19 103 121 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 2.5E-19 233 250 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00385 8.6E-11 244 261 IPR001128 Cytochrome P450 PRINTS PR00463 2.5E-19 253 279 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 2.5E-19 297 315 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00385 8.6E-11 298 309 IPR001128 Cytochrome P450 PRINTS PR00463 2.5E-19 337 361 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 2.5E-19 374 384 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00385 8.6E-11 375 384 IPR001128 Cytochrome P450 ProSitePatterns PS00086 NA 377 386 IPR017972 Cytochrome P450, conserved site PRINTS PR00385 8.6E-11 384 395 IPR001128 Cytochrome P450 PRINTS PR00463 2.5E-19 384 407 IPR002401 Cytochrome P450, E-class, group I