Basic information
Locus name	AT4G22880
Alias	ANS/ LDOX
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling
Effect for Senescence	unclear
Gene Description	encodes leucoanthocyanidin dioxygenase, which is involved in proanthocyanin biosynthesis. Mutant analysis suggests that this gene is also involved in vacuole formation.
Evidence	Molecular evidence:Blast search [Ref 1]
References	1: Snowden KC, Simkin AJ, Janssen BJ, Templeton KR, Loucas HM, Simons JL, Karunairetnam S, Gleave AP, Clark DG, Klee HJ The Decreased apical dominance1/Petunia hybrida CAROTENOID CLEAVAGE DIOXYGENASE8 gene affects branch production and plays a role in leaf senescence, root growth, and flower development. Plant Cell 2005 Mar;17(3):746-59
Gene Ontology	biological process oxidation-reduction process molecular function oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors oxidoreductase activity
Sequence	AT4G22880.1 | Genomic | mRNA | CDS | Protein AT4G22880.2 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_170107	Accession Taxon NP_001031700 ( AT4G22880 ) Arabidopsis thaliana NP_194019 Arabidopsis thaliana NP_001043065 Oryza sativa Japonica Group NP_001058119 Oryza sativa Japonica Group
Cross Link
Database Entry ID E-value Start End InterPro ID Description SUPERFAMILY SSF51197 6.3E-107 4 343 No hit NA PANTHER PTHR10209 6.5E-127 7 340 No hit NA Pfam PF14226 4.5E-27 47 160 IPR026992 Non-haem dioxygenase N-terminal domain ProSiteProfiles PS51471 14.3 208 307 IPR005123 Oxoglutarate/iron-dependent dioxygenase Pfam PF03171 6.2E-24 211 307 IPR005123 Oxoglutarate/iron-dependent dioxygenase
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787