Basic information
Locus name	AT1G04580
Alias	AAO4
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation
Effect for Senescence	unclear
Gene Description	ARABIDOPSIS ALDEHYDE OXIDASE 4 (AAO4); FUNCTIONS IN: aryl-aldehyde oxidase activity, aldehyde oxidase activity; INVOLVED IN: glucosinolate metabolic process, abscisic acid biosynthetic process. Gene expression is increased during leaf senescence.
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process oxidation-reduction process molecular function electron carrier activity iron ion binding iron-sulfur cluster binding metal ion binding oxidoreductase activity
Sequence	AT1G04580.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_127252	Accession Taxon NP_001077966 Arabidopsis thaliana NP_180283 Arabidopsis thaliana NP_189946 Arabidopsis thaliana NP_195215 Arabidopsis thaliana NP_195216 Arabidopsis thaliana NP_563711 ( AT1G04580 ) Arabidopsis thaliana NP_568407 Arabidopsis thaliana NP_851049 Arabidopsis thaliana 117669 Chlamydomonas reinhardtii ACO65070 Micromonas sp. RCC299 NP_001050420 Oryza sativa Japonica Group NP_001051517 Oryza sativa Japonica Group NP_001051518 Oryza sativa Japonica Group NP_001058964 Oryza sativa Japonica Group NP_001059379 Oryza sativa Japonica Group NP_001064133 Oryza sativa Japonica Group e_gw1.170.7.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_440069 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_930001 Physcomitrella patens subsp. patens 29976.m000486 Ricinus communis 30169.m006431 Ricinus communis 47744.m000020 Ricinus communis estExt_thaps1_ua_kg.C_chr_220040 Thalassiosira pseudonana CCMP1335 XP_002953715 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PIRSF PIRSF000127 0.0 1 1337 IPR016208 Aldehyde oxidase/xanthine dehydrogenase ProSiteProfiles PS51085 10.3 4 91 IPR001041 2Fe-2S ferredoxin-type domain PANTHER PTHR11908 0.0 6 1334 No hit NA SUPERFAMILY SSF54292 2.8E-20 6 91 IPR001041 2Fe-2S ferredoxin-type domain Pfam PF00111 9.1E-8 9 76 IPR001041 2Fe-2S ferredoxin-type domain ProSitePatterns PS00197 NA 43 51 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site Pfam PF01799 4.2E-20 87 168 IPR002888 [2Fe-2S]-binding SUPERFAMILY SSF47741 3.5E-29 94 211 IPR002888 [2Fe-2S]-binding SUPERFAMILY SSF56176 2.8E-44 195 406 IPR016166 FAD-binding, type 2 ProSiteProfiles PS51387 19.7 225 409 IPR016166 FAD-binding, type 2 Pfam PF00941 1.4E-40 229 407 IPR002346 Molybdopterin dehydrogenase, FAD-binding SUPERFAMILY SSF55447 1.6E-12 416 526 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMART SM01092 5.4E-7 418 526 IPR005107 CO dehydrogenase flavoprotein, C-terminal Pfam PF03450 1.0E-16 419 524 IPR005107 CO dehydrogenase flavoprotein, C-terminal SUPERFAMILY SSF54665 9.8E-35 557 691 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Pfam PF01315 2.1E-31 581 690 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMART SM01008 1.9E-24 581 691 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SUPERFAMILY SSF56003 6.4E-156 695 1288 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding Pfam PF02738 4.6E-185 702 1240 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding
Subcellular Localization
Localization	cytosol,plasma membrane
Evidence	SUBAcon
Pubmed ID	23180787