Basic information
Locus name	AT1G08110
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Signal transduction (cadmium)
Effect for Senescence	unclear
Gene Description	lactoylglutathione lyase, putative / glyoxalase I, putative; FUNCTIONS IN: calmodulin binding, lactoylglutathione lyase activity; INVOLVED IN: response to cadmium ion, carbohydrate metabolic process. Gene expression is increased during leaf senescence.
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	molecular function lactoylglutathione lyase activity metal ion binding
Pathway	KEGG map00620 (EC 4.4.1.5) MetaCyc PWY-5386
Sequence	AT1G08110.1 | Genomic | mRNA | CDS | Protein AT1G08110.2 | Genomic | mRNA | CDS | Protein AT1G08110.3 | Genomic | mRNA | CDS | Protein AT1G08110.4 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_127627	Accession Taxon NP_001030995 Arabidopsis thaliana NP_001030996 ( AT1G08110 ) Arabidopsis thaliana NP_001031026 Arabidopsis thaliana NP_172291 Arabidopsis thaliana NP_849609 Arabidopsis thaliana CMD108C Cyanidioschyzon merolae strain 10D CMR395C Cyanidioschyzon merolae strain 10D 106176 Chlamydomonas reinhardtii ACO63051 Micromonas sp. RCC299 NP_001055113 Oryza sativa Japonica Group fgenesh1_pg.C_Chr_06.0001000300 Ostreococcus tauri estExt_fgenesh1_pm.C_1200006 Physcomitrella patens subsp. patens fgenesh1_pm.scaffold_444000001 Physcomitrella patens subsp. patens 29589.m001237 Ricinus communis 29912.m005471 Ricinus communis e_gw1.1.712.1 Thalassiosira pseudonana CCMP1335 XP_002956590 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR10374 3.0E-69 3 173 No hit NA TIGRFAM TIGR00068 6.8E-66 16 180 IPR004361 Glyoxalase I SUPERFAMILY SSF54593 2.4E-35 25 173 No hit NA Pfam PF00903 1.2E-24 30 171 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain ProSitePatterns PS00934 NA 30 51 IPR018146 Glyoxalase I, conserved site ProSitePatterns PS00935 NA 115 131 IPR018146 Glyoxalase I, conserved site
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787