Basic information
Locus name	AT1G08720
Alias	EDR1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification
Effect for Senescence	delay
Gene Description	ENHANCED DISEASE RESISTANCE 1 (EDR1); FUNCTIONS IN: protein serine/threonine/tyrosine kinase activity, MAP kinase kinase kinase activity, kinase activity. Gene expression is increased during leaf senescence.
Evidence	Genomic evidence:microarray data [Ref 1]; Genetic evidence: Mutant [Ref 2]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94 2: Pan H, Liu S, Tang D HPR1, a component of the THO/TREX complex, plays an important role in disease resistance and senescence in Arabidopsis. Plant J. 2012 Mar;69(5):831-43
Gene Ontology	biological process protein phosphorylation molecular function protein kinase activity
Sequence	AT1G08720.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name edr1 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type EMS
Mutated 2 Mutant name hpr1-4 edr1 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type EMS
Ortholog Group
Ortholog Groups: OG5_130251	Accession Taxon NP_173254 Arabidopsis thaliana NP_177507 Arabidopsis thaliana NP_196746 Arabidopsis thaliana NP_563824 ( AT1G08720 ) Arabidopsis thaliana CMD015C Cyanidioschyzon merolae strain 10D 102541 Chlamydomonas reinhardtii ACO62560 Micromonas sp. RCC299 ACO66955 Micromonas sp. RCC299 NP_001046319 Oryza sativa Japonica Group NP_001048096 Oryza sativa Japonica Group NP_001049035 Oryza sativa Japonica Group NP_001057225 Oryza sativa Japonica Group NP_001064663 Oryza sativa Japonica Group e_gw1.14.00.209.1 Ostreococcus tauri estExt_gwp_GeneWisePlus.C_Chr_12.00010034 Ostreococcus tauri 29794.m003325 Ricinus communis 30128.m008649 Ricinus communis XP_002957185 Volvox carteri f. nagariensis XP_002957187 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR23257 3.0E-206 13 933 No hit NA Pfam PF14381 2.1E-71 128 328 IPR026840 Armadillo repeat-containing protein 3 and Serine/threonine-protein kinase CTR1 SUPERFAMILY SSF56112 8.0E-81 657 920 IPR011009 Protein kinase-like domain ProSiteProfiles PS50011 42.3 669 925 IPR000719 Protein kinase, catalytic domain SMART SM00220 9.1E-57 669 924 IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain Pfam PF07714 9.1E-64 670 921 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain ProSitePatterns PS00107 NA 675 697 IPR017441 Protein kinase, ATP binding site PRINTS PR00109 3.8E-12 743 756 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain PRINTS PR00109 3.8E-12 782 800 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain ProSitePatterns PS00108 NA 788 800 IPR008271 Serine/threonine-protein kinase, active site PRINTS PR00109 3.8E-12 829 839 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain PRINTS PR00109 3.8E-12 848 870 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain PRINTS PR00109 3.8E-12 892 914 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787